Patents by Inventor Yangsheng Qiu

Yangsheng Qiu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL CONJUGATE MOLECULES TARGETING CD39 AND TGFBETA
    Publication number: 20230416394
    Abstract: Provided are conjugate molecules comprising a CD39 inhibitory portion capable of interfering interaction between CD39 and its substrate, and a TGF ? inhibitory portion capable of interfering interaction between TGF ? and its receptor, isolated polynucleotides encoding the same, pharmaceutical compositions comprising the same and the uses thereof.
    Type: Application
    Filed: November 25, 2021
    Publication date: December 28, 2023
    Inventors: Dawei SUN, Zhihao WU, Jun SUN, Yanan GENG, Rui GAO, Lili TANG, Qinglin DU, Yangsheng QIU, Robert H. ARCH, Hongtao LU
  • CD47 antigen binding unit and uses thereof
    Patent number: 11267885
    Abstract: Disclosed herein are antigen binding units that specifically bind to CD47. Further disclosed herein are polynucleic acids encoding said antigen binding units, vectors comprising said polynucleic acids, and hybridomas and host cells comprising said vectors. Further provided herein are methods for inducing phagocytosis of CD47-expressing cells.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: March 8, 2022
    Assignee: ZLIP HOLDING LIMITED
    Inventors: Yangsheng Qiu, Jing Li, Honghai Gao, Fenglan Wu, Xu Fang, Shou Li, Hongtao Lu, James S. Yan, Lei Shi
  • NOVEL ANTI-CD39 ANTIBODIES
    Publication number: 20210388105
    Abstract: Provided are anti-CD39 antibodies or antigen-binding fragments thereof, isolated polynucleotides encoding the same, pharmaceutical compositions comprising the same and the uses thereof.
    Type: Application
    Filed: August 26, 2020
    Publication date: December 16, 2021
    Inventors: Yangsheng QIU, Meiling SUN, Roumei XING, Dan XU, Yufei SHI, Jinfeng ZHAO, Qinglin DU, Zhihao WU, Rui GAO, Robert H. ARCH, Hongtao LU
  • NOVEL ANTI-SIRPA ANTIBODIES
    Publication number: 20210347908
    Abstract: Provided are anti-SIRP? antibodies or antigen-binding fragments thereof, isolated polynucleotides encoding the same, pharmaceutical compositions comprising the same and the uses thereof.
    Type: Application
    Filed: August 18, 2020
    Publication date: November 11, 2021
    Inventors: Xiaofeng NIU, Jingfeng YU, Jinfeng ZHAO, Fengli WANG, Dan XU, Roumei XING, Zhihao WU, Qinglin DU, Yangsheng QIU, Robert H. ARCH, Hongtao LU
  • BINDING AGONIST FOR TREATMENT OF NEUROLOGICAL AND OTHER DISORDERS
    Publication number: 20210347902
    Abstract: The present invention relates to TrkB binding agonists, and to the use of such agonists in the treatment of neurological disorders and other disorders. The present invention also relates to specific TrkB binding agonists comprising CDRs, variable regions, heavy and light chains, and variant sequences thereof.
    Type: Application
    Filed: June 14, 2021
    Publication date: November 11, 2021
    Inventors: Tejinder Kaur BHINDER, Chong DING, Xu FENG, Wenqing JIANG, Alan Peter LEWIS, Yingli MA, Guhan NAGAPPAN, Radha Shah PARMAR, Yangsheng QIU, Liuqing YANG, Qing ZHANG, Yanjiao ZHOU
  • Binding agonist for treatment of neurological and other disorders
    Patent number: 11078287
    Abstract: The present invention relates to TrkB binding agonists, and to the use of such agonists in the treatment of neurological disorders and other disorders. The present invention also relates to specific TrkB binding agonists comprising CDRs, variable regions, heavy and light chains, and variant sequences thereof.
    Type: Grant
    Filed: November 15, 2016
    Date of Patent: August 3, 2021
    Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
    Inventors: Tejinder Kaur Bhinder, Chong Ding, Xu Feng, Wenqing Jiang, Alan Peter Lewis, Yingli Ma, Guhan Nagappan, Radha Shah Parmar, Yangsheng Qiu, Liuqing Yang, Qing Zhang, Yanjiao Zhou
  • Monoclonal antibody FnAb8 and application thereof
    Patent number: 10995142
    Abstract: Provided in the present invention are a monoclonal antibody FnAb8 and application thereof.
    Type: Grant
    Filed: January 11, 2017
    Date of Patent: May 4, 2021
    Assignee: Shanghai Jiaotong University
    Inventors: Yuhong Xu, Yangsheng Qiu
  • CD47 ANTIGEN BINDING UNIT AND USES THEREOF
    Publication number: 20200247886
    Abstract: Disclosed herein are antigen binding units that specifically bind to CD47. Further disclosed herein are polynucleic acids encoding said antigen binding units, vectors comprising said polynucleic acids, and hybridomas and host cells comprising said vectors. Further provided herein are methods for inducing phagocytosis of CD47-expressing cells.
    Type: Application
    Filed: January 26, 2018
    Publication date: August 6, 2020
    Inventors: Yangsheng QIU, Jing LI, Honghai GAO, Fenglan WU, Xu FANG, Shou LI, Hongtao Lu, James S. YAN, Lei SHI
  • BINDING AGONIST FOR TREATMENT OF NEUROLOGICAL AND OTHER DISORDERS
    Publication number: 20200165345
    Abstract: The present invention relates to TrkB binding agonists, and to the use of such agonists in the treatment of neurological disorders and other disorders. The present invention also relates to specific TrkB binding agonists comprising CDRs, variable regions, heavy and light chains, and variant sequences thereof.
    Type: Application
    Filed: November 15, 2016
    Publication date: May 28, 2020
    Inventors: Tejinder Kaur BHINDER, Chong DING, Xu FENG, Wenqing JIANG, Alan Peter LEWIS, Yingli MA, Guhan NAGAPPAN, Radha Shah PARMAR, Yangsheng QIU, Liuqing YANG, Qing ZHANG, Yanjiao ZHOU
  • MONOCLONAL ANTIBODY FnAb8 AND APPLICATION THEREOF
    Publication number: 20190023785
    Abstract: Provided in the present invention are a monoclonal antibody FnAb8 and application thereof.
    Type: Application
    Filed: January 11, 2017
    Publication date: January 24, 2019
    Inventors: Yuhong XU, Yangsheng QIU
  • Binding agonist for treatment of neurological and other disorders
    Patent number: 9914781
    Abstract: The present invention relates to TrkB binding agonists, and to the use of such agonists in the treatment of neurological disorders and other disorders. The present invention also relates to specific TrkB binding agonists comprising CDRs, variable regions, heavy and light chains, and variant sequences thereof.
    Type: Grant
    Filed: November 15, 2016
    Date of Patent: March 13, 2018
    Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
    Inventors: Tejinder Kaur Bhinder, Chong Ding, Xu Feng, Wenqing Jiang, Alan Peter Lewis, Yingli Ma, Guhan Nagappan, Radha Shah Parmar, Yangsheng Qiu, Liuqing Yang, Qing Zhang, Yanjiao Zhou