Abstract: The present disclosure relates to the technical field of lamp bulb, and discloses a shadowless waterproof light-emitting diode (LED) lamp bulb, including a lamp holder and a lampshade connected to the lamp holder, and further including a lampwick component and a sealing plug; the lampwick component includes a base plate, a first metal support line, and a second metal support line; and the other end of the first metal support line and the other end of the second metal support line are both electrically connected to the lamp holder. The present disclosure has the following advantages: 1. The structure of a luminous element is improved, which effectively solves the technical problem of light shadow generated by the lamp bulb during use; 2. The lamp bulb has a novel structure and higher decorability; and 3. The overall lamp bulb is convenient to assemble and higher in production and assembling efficiency.

Abstract: A sampling device and method for evaluating ecological risk of soil in a high geological background area comprises an impact sampling mechanism, a soil layer stripping mechanism and an auxiliary support frame. The impact sampling mechanism comprises a sampling hopper with a downward opening. A connecting sliding rod is fixedly arranged on the top of the sampling hopper. An upper end of the connecting sliding rod is connected with an impact rod. The impact rod is internally provided with an impact hammer capable of reciprocating along an axis of the impact rod. The soil layer stripping mechanism comprises a stripping sliding cylinder in sliding fit with the connecting sliding rod, and a support disc. A plurality of stripping plates are connected to a lower side edge of the support disc in a sliding fit mode.

Abstract: The present disclosure relates to the field of environment monitoring equipment, and in particular, to a device for determining threshold wind speed in intermittent wind-sand flow. The device includes a base. A rotary bearing is installed on the base. A circuitry is installed in the base. A telescopic rod is installed through the rotary bearing. A wind driven vane and an earth surface wind-sand monitoring frame are installed on the telescopic rod. Photoelectric induction probes are installed on the earth surface wind-sand monitoring frame.

Abstract: A sampling device and method for evaluating ecological risk of soil in a high geological background area comprises an impact sampling mechanism, a soil layer stripping mechanism and an auxiliary support frame. The impact sampling mechanism comprises a sampling hopper with a downward opening. A connecting sliding rod is fixedly arranged on the top of the sampling hopper. An upper end of the connecting sliding rod is connected with an impact rod. The impact rod is internally provided with an impact hammer capable of reciprocating along an axis of the impact rod. The soil layer stripping mechanism comprises a stripping sliding cylinder in sliding fit with the connecting sliding rod, and a support disc. A plurality of stripping plates are connected to a lower side edge of the support disc in a sliding fit mode.

Abstract: In certain aspects, a three-dimensional (3D) memory device includes a first semiconductor structure, a second semiconductor structure, and a bonding interface between the first semiconductor structure and the second semiconductor structure. The first semiconductor structure includes an array of memory cells, a first peripheral circuit of the array of memory cells, and a polysilicon layer between the array of memory cells and the first peripheral circuit. The first peripheral circuit includes a first transistor. The second semiconductor structure includes a second peripheral circuit of the array of memory cells. The second peripheral circuit includes a second transistor.

Abstract: In certain aspects, a three-dimensional (3D) memory device includes a first semiconductor structure, a second semiconductor structure, a third semiconductor structure, and a first bonding interface between the first semiconductor structure and the second semiconductor structure. The first semiconductor structure includes an array of memory cells. The second semiconductor structure includes a first peripheral circuit of the array of memory cells. The first peripheral circuit includes a first transistor. A third semiconductor structure includes a second peripheral circuit of the array of memory cells. The second peripheral circuit includes a second transistor. The first semiconductor structure, the second semiconductor structure, and the third semiconductor structure are stacked over one another.

Abstract: Provided herein are phenylalanine ammonia-lyase (PAL) variants produced by prokaryotes, wherein such prokaryotic PAL variant has a greater phenylalanine-converting activity and/or a reduced immunogenicity as compared to a wild-type PAL. Further provided are compositions of prokaryotic PAL and biologically active fragments, mutants, variants or analogs thereof, as well as methods for the production, purification, formulation, and use of such compositions for industrial and therapeutic purposes, e.g., treating hyperphenylalaninemia, including phenylketonuria, and other disorders, including cancer.

Abstract: The present invention provides process for enriching adeno-associated virus particles using anion exchange chromatography and zonal ultracentrifugation.

Abstract: A semiconductor structure includes a substrate, a first electrode plate over the substrate, a second electrode plate over the first electrode plate, and a sidewall structure. The sidewall structure is attached to a side of the second electrode plate. A dielectric constant of the sidewall structure decreases in a direction away from the second electrode plate.

Abstract: The present invention provides use of substance A in the preparation of a medicament. The substance A is a naphthylurea compound as shown in formula I, a pharmaceutically acceptable salt thereof, a solvate thereof, a solvate of the pharmaceutically acceptable salt thereof, a crystal form thereof or a tautomer thereof, and the medicament is a medicament for treating a corneal neovascular disease. The naphthylurea compound of the present invention can treat the corneal neovascular disease by means of eye dropping administration.

Abstract: The present disclosure provides a semiconductor structure and a manufacturing method thereof. The manufacturing method of a semiconductor structure includes providing a substrate having trenches, regions other than the trenches in the substrate form a plurality of active regions at intervals; forming a first isolation layer and a second isolation layer, a top surface of the first isolation layer is lower than a top surface of the second isolation layer, a groove is formed between the second isolation layer and the active region; forming a barrier layer in the groove, an etching rate of the barrier layer is lower than an etching rate of the first isolation layer; and forming a third isolation layer in an intermediate trench, the intermediate trench is filled with the third isolation layer, and the first isolation layer, the second isolation layer, the third isolation layer, and the barrier layer form an isolation structure.

Abstract: Provided herein are phenylalanine ammonia-lyase (PAL) variants produced by prokaryotes, wherein such prokaryotic PAL variant has a greater phenylalanine-converting activity and/or a reduced immunogenicity as compared to a wild-type PAL. Further provided are compositions of prokaryotic PAL and biologically active fragments, mutants, variants or analogs thereof, as well as methods for the production, purification, formulation, and use of such compositions for industrial and therapeutic purposes, e.g., treating hyperphenylalaninemia, including phenylketonuria, and other disorders, including cancer.

Abstract: A polyvinylidene fluoride (PVDF) casting membrane solution is shaped as a flat sheet membrane by thermally induced phase separation (TIPS), the PVDF membrane is defluorinated with an alkaline potassium permanganate solution, and then the carbon chain is extended with glycidyl methacrylate (GMA) as the graft monomer, and finally the nucleophilic substitution is carried out between melamine and GMA to produce a chelating microfiltration membrane for capturing and enriching heavy metals with high flux and high capacity.

Abstract: A method and a device for synchronous high-speed photographing of microparticle rotation in a liquid cyclone field and for determining the rotation velocity of a microparticle in a liquid cyclone field by using a combination of a synchronous high-speed photographing system and a transparent microparticle containing two centrosymmetrically arranged inner cores having the same diameter. The method comprises: using a transparent microparticle comprising two inner cores having the same diameter and arranged centrosymmetrically as a rotation test particle; acquiring synchronously two groups of two dimensional image series of microparticle motion in a liquid cyclone field using two orthogonally arranged high-speed digital cameras; and reconstructing a three dimensional motion trajectory of the microparticle from the two groups of synchronous image series, and determining a rotation velocity of the microparticle in the cyclone field at the same time.

Abstract: Provided herein are phenylalanine ammonia-lyase (PAL) variants produced by prokaryotes, wherein such prokaryotic PAL variant has a greater phenylalanine-converting activity and/or a reduced immunogenicity as compared to a wild-type PAL. Further provided are compositions of prokaryotic PAL and biologically active fragments, mutants, variants or analogs thereof, as well as methods for the production, purification, formulation, and use of such compositions for industrial and therapeutic purposes, e.g., treating hyperphenylalaninemia, including phenylketonuria, and other disorders, including cancer.

Abstract: The present invention discloses a breeding method for obtaining heterosis in lined seahorses, which comprises the following steps: S1, selecting parents of lined seahorse from populations with great differences in genetic background; S2, intensified rearing the parents before pregnancy; S3, matching and breeding the parents of lined seahorse from different geographical populations according to complete diallel cross method; S4, finely nursing pregnant seahorses; S5, respectively collecting all postlarvae (filial generations) hatched by each breeding group in one week; S6, rearing the filial generations; and S7, comparing survival rate and growth performance of filial generations. The present invention, via hybridization of different geographical populations to obtain lined seahorse, makes effective use of heterosis. Survival rate and growth rate of filial generations are apparently enhanced compared to that of those filial generations without hybridization.

Abstract: Provided herein are phenylalanine ammonia-lyase (PAL) variants produced by prokaryotes, wherein such prokaryotic PAL variant has a greater phenylalanine-converting activity and/or a reduced immunogenicity as compared to a wild-type PAL. Further provided are compositions of prokaryotic PAL and biologically active fragments, mutants, variants or analogs thereof, as well as methods for the production, purification, formulation, and use of such compositions for industrial and therapeutic purposes, e.g., treating hyperphenylalaninemia, including phenylketonuria, and other disorders, including cancer.

Abstract: A polyvinylidene fluoride (PVDF) casting membrane solution is shaped as a flat sheet membrane by thermally induced phase separation (TIPS), the PVDF membrane is defluorinated with an alkaline potassium permanganate solution, and then the carbon chain is extended with glycidyl methacrylate (GMA) as the graft monomer, and finally the nucleophilic substitution is carried out between melamine and GMA to produce a chelating microfiltration membrane for capturing and enriching heavy metals with high flux and high capacity.

Abstract: A method and a device for synchronous high-speed photographing of microparticle rotation in a liquid cyclone field and for determining the rotation velocity of a microparticle in a liquid cyclone field by using a combination of a synchronous high-speed photographing system and a transparent microparticle containing two centrosymmetrically arranged inner cores having the same diameter. The method comprises: using a transparent microparticle comprising two inner cores having the same diameter and arranged centrosymmetrically as a rotation test particle; acquiring synchronously two groups of two dimensional image series of microparticle motion in a liquid cyclone field using two orthogonally arranged high-speed digital cameras; and reconstructing a three dimensional motion trajectory of the microparticle from the two groups of synchronous image series, and determining a rotation velocity of the microparticle in the cyclone field at the same time.