Abstract: Personal care compositions are disclosed herein. In accordance with an aspect, provided is a personal care composition comprising: (a) a surfactant system comprising at least one anionic surfactant and at least one amphoteric surfactant; and (b) at least one tear film protecting agent, wherein the personal care composition has a pH ranging from about 4.0 to about 6.0.

Abstract: The present disclosure discloses an ultrasound pupil change-based anesthesia depth monitoring system, including: an ultrasound monitoring apparatus, which includes a head-mounted mounting member and two miniature ultrasonic probes, the two miniature ultrasonic probes being symmetrically arranged at both sides of the head-mounted mounting member, and the miniature ultrasonic probes abutting against the face and obtaining ultrasonic pupil images by means of ultrasonic waves; an ultrasound host, which includes a display, the ultrasonic pupil images obtained by the miniature ultrasonic probes being transmitted to the ultrasound host, and the ultrasound host processing the ultrasonic pupil images and displaying pupil images, real-time change values of diameters of pupils, and the like by means of the display; and a shading patch, which is applied to the eyelids. The present disclosure further discloses a detection method of an ultrasound pupil change-based anesthesia depth monitoring system.

Abstract: Disclosed are a isoindoline derivative, an intermediate thereof, a preparation method therefor, a pharmaceutical composition thereof and the use thereof. The isoindoline derivatives of the present invention can specifically target and regulate various proteins by binding to Cereblon, thereby effectively treating cancers and other related diseases.

Abstract: Disclosed are personal care compositions, e.g., natural liquid soap compositions, comprising an effective amount of a long chain alkyl (C6-C22) anionic surfactant (e.g., disodium 2-sulfolaurate), an effective amount of an amphoteric surfactant (e.g., cocamidopropyl betaine), an effective amount of one or more alkyl glucoside(s) (e.g., decyl glucoside and coco-glucoside); and water, as well as to methods of using these compositions.