Patents by Inventor Yanli Gu

Yanli Gu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chimeric antigen receptor and application thereof
    Patent number: 12221475
    Abstract: Provided are a chimeric antigen receptor and an application thereof; said chimeric antigen receptor contains a domain which identifies any one of, or a combination of at least two of, the malarial protein VAR2CSA, a protein tag on malarial protein VAR2CSA, or a compound capable of labeling the malarial protein VAR2CSA. The chimeric antigen receptor can identify the VAR2CSA protein or the recombinant protein (rVAR2) of any one of, or at least two of, the domains of the VAR2CSA protein which can bind to placental-like chondroitin sulfate A (pl-CSA). The VAR2CSA protein or rVAS2 protein is capable of targeting several different types of tumor cells by means of binding to the pl-CSA on the surface of the tumor cell.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: February 11, 2025
    Assignee: CAS Lamvac (Guangzhou) Biomedical Technology Co., Ltd.
    Inventors: Wen Hu, Yongchao Yao, Wenzhong Guo, Yinbo Jiang, Shuozhou Huang, Ting Jiang, Jiaojiao Li, Zhu Tao, Yanli Gu, Huihui Zhang, Li Qin, Xiaoping Chen
  • COMBINED FORMULATION KIT FOR ANALYZING PHENOTYPE AND FUNCTION OF CD1C+DENRTIC CELL SUBSET AND USE THEREOF
    Publication number: 20220214347
    Abstract: Disclosed are a combined formulation kit for analyzing the phenotype and function of a CD1c+ dendritic cell subset and the use thereof, wherein the detection objects of the kit include CD1c, CD40, IL-6 and IL-10. The kit can be used to efficiently and quickly identify the phenotype of a CD1c+ dendritic cell subset in peripheral blood and analyze the function thereof, thereby ensuring accuracy and reducing the economic cost produced by detecting a large number of surface antigen molecules, and the detection method is also simple to implement.
    Type: Application
    Filed: December 18, 2019
    Publication date: July 7, 2022
    Inventors: Fang Zhou, Xiaoping Chen, Li Qin, Yanli Gu, Wenlong Xu, Yong Lu, Xu Chang, Guojian Wei, Zhien Rong
  • CHIMERIC ANTIGEN RECEPTOR AND APPLICATION THEREOF
    Publication number: 20210221880
    Abstract: Provided are a chimeric antigen receptor and an application thereof; said chimeric antigen receptor contains a domain which identifies any one of, or a combination of at least two of, the malarial protein VAR2CSA, a protein tag on malarial protein VAR2CSA, or a compound capable of labeling the malarial protein VAR2CSA. The chimeric antigen receptor can identify the VAR2CSA protein or the recombinant protein (rVAR2) of any one of, or at least two of, the domains of the VAR2CSA protein which can bind to placental-like chondroitin sulfate A (pl-CSA). The VAR2CSA protein or rVAS2 protein is capable of targeting several different types of tumor cells by means of binding to the pl-CSA on the surface of the tumor cell.
    Type: Application
    Filed: November 29, 2017
    Publication date: July 22, 2021
    Inventors: Wen Hu, Yongchao Yao, Wenzhong Guo, Yinbo Jiang, Shuozhou Huang, Ting Jiang, Jiaojiao Li, Zhu Tao, Yanli Gu, Huihui Zhang, Li Qin, Xiaoping Chen