Patents by Inventor Yann-Lii LEU

Yann-Lii LEU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USES OF CORYLIN AND/OR NEOBAVAISOFLAVONE IN TREATING SYMPTOMS ASSOCIATED WITH SENESCENCE
    Publication number: 20240091191
    Abstract: Disclosed herein is related to a method for treating a symptom associated with senescence in a subject by administering to the subject with an effective amount of corylin and/or neobavaisoflavone, wherein the symptom associated with senescence is loss of muscle strength, muscle weakness, loss of motor coordination, loss of balance, skin wrinkle, or a poor blood biochemical parameter.
    Type: Application
    Filed: September 2, 2022
    Publication date: March 21, 2024
    Applicant: Chang Gung University
    Inventors: Chin-Chuan CHEN, Yann-Lii LEU, Shu-Huei WANG, Tong-Hong WANG, Shu-Fang CHENG
  • METHOD FOR ENHANCING DELIVERY OF THERAPEUTIC DRUGS TO TREATMENT SITES
    Publication number: 20190133979
    Abstract: Disclosed herein is a method for enhancing uptake of magnetic nanoparticles (MNPs) having a therapeutic agent associated therein to a target site (e.g., a tumor), thereby resulting in elevated level of therapeutic agents being accumulated in the target site. The method comprises concurrently administering a sufficient amount of a polyphenolic compound and MNPs to the target site. Also disclosed herein is a method for treating a cancer in a subject. The method comprises concurrently administering an effective amount of the polyphenolic compound and MNPs to the subject, so as to ameliorate or alleviate symptoms associated with the cancer.
    Type: Application
    Filed: January 2, 2019
    Publication date: May 9, 2019
    Applicant: Chang Gung University
    Inventors: Yunn-Hwa MA, Yann-Lii LEU, Jender WU, Kuo-Chen WEI, Yi-Ching LU
  • Mammalian TOR inhibitor
    Patent number: 9795588
    Abstract: A method for inhibiting mammalian TOR in a cell, comprising: providing a compound of formula (1): and incubating the cell with the compound. Also provided is a method for extending life span of a subject, comprising: providing the compound; and administering the compound to the subject. Yet also provided is a method for treating a mammalian TOR activation-caused disease in a subject, comprising: providing the compound; and administering the compound to the subject.
    Type: Grant
    Filed: August 2, 2016
    Date of Patent: October 24, 2017
    Assignee: Chang Gung University
    Inventors: Chin-Chuan Chen, Yann-Lii Leu, Shu-Huei Wang
  • MAMMALIAN TOR INHIBITOR
    Publication number: 20170231947
    Abstract: A method for inhibiting mammalian TOR in a cell, comprising: providing a compound of formula (1): and incubating the cell with the compound. Also provided is a method for extending life span of a subject, comprising: providing the compound; and administering the compound to the subject. Yet also provided is a method for treating a mammalian TOR activation-caused disease in a subject, comprising: providing the compound; and administering the compound to the subject.
    Type: Application
    Filed: August 2, 2016
    Publication date: August 17, 2017
    Inventors: Chin-Chuan Chen, Yann-Lii Leu, Shu-Huei Wang
  • MAMMALIAN SIRT1 ACTIVATOR
    Publication number: 20170035724
    Abstract: A method for activating mammalian SIRT1 in a cell comprising: providing a compound of formula (1): and incubating the cell with the compound. Also provided is a method for extending life span of a subject comprising: providing the same compound; and administering the compound to the subject. Yet also provided is a method for treating a mammalian SIRT1 inactivation-related disease in a subject comprising: providing the same compound; and administering the compound to the subject.
    Type: Application
    Filed: October 16, 2015
    Publication date: February 9, 2017
    Inventors: Chin-Chuan CHEN, Yann-Lii LEU, Tsong-Long HWANG, Jia-You FANG, Tai-Long PAN