Patents by Inventor Yann-Yu Lu

Yann-Yu Lu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LIPIDS AND USES THEREOF
    Publication number: 20250034088
    Abstract: The present disclosure provides an ionizable amine-containing lipid. Particularly, the ionizable amine-containing lipid is able to deliver a nucleic acid.
    Type: Application
    Filed: July 8, 2024
    Publication date: January 30, 2025
    Applicant: TAIWAN BIO-MANUFACTURING CORPORATION
    Inventors: SHAO-ZHENG PENG, JIAO-REN HUANG, KING LAM, YANN-YU LU
  • Hetroarylamine compounds for modulating the hedgehog pathway and preparing method and uses thereof
    Patent number: 10793542
    Abstract: The present invention provides a compound of formula (1): wherein X, Y, Z1, Z2, R1, R2, A, B, p and q are as disclosed in the specification. A pharmaceutical composition and a method for modulating the Hedgehog pathway are also provided. The present invention rurthe r provides a process for preparing the compound.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: October 6, 2020
    Assignee: DEVELOPMENT CENTER FOR BIOTECHNOLOGY
    Inventors: Mann-Yan Kuo, Ying-Shuan Lee, Yann-Yu Lu, Chia-Wei Liu, Seline Hsieh, Ju-Ying Yang
  • HETROARYLAMINE COMPOUNDS FOR MODULATING THE HEDGEHOG PATHWAY AND PREPARING METHOD AND USES THEREOF
    Publication number: 20200079753
    Abstract: The present invention provides a compound of formula (I) wherein X, Y, Z1, Z2, R1, R2, A, B, p and q are as disclosed in the specification. A pharmaceutical composition and a method for modulating the Hedgehog pathway are also provided. The present invention further provides a process for preparing the compound.
    Type: Application
    Filed: November 22, 2017
    Publication date: March 12, 2020
    Applicant: DEVELOPMENT CENTER FOR BIOTECHNOLOGY
    Inventors: MANN-YAN KUO, YING-SHUAN LEE, YANN-YU LU, CHIA-WEI LIU, SELINE HSIEH, JU-YING YANG
  • Pyrimidine compounds as mTOR and PI3K inhibitors
    Patent number: 9801888
    Abstract: The present invention relates to pyrimidine compounds of formula (I): which are useful in treating mTOR kinase- or PI3K kinase-related diseases.
    Type: Grant
    Filed: January 21, 2016
    Date of Patent: October 31, 2017
    Assignee: DEVELOPMENT CENTER FOR BIOTECHNOLOGY
    Inventors: Mann-Yan Kuo, Ying-Shuan Lee, Paonien Chen, Li Jung Chen, Yann Yu Lu, Yi-Ting Huang, Hung-Yi Hsu, Ping-Kuei Tsai
  • NOVEL PYRIMIDINE COMPOUNDS AS mTOR AND PI3K INHIBITORS
    Publication number: 20160136176
    Abstract: The present invention relates to pyrimidine compounds of formula (I): which are useful in treating mTOR kinase- or PI3K kinase-related diseases.
    Type: Application
    Filed: January 21, 2016
    Publication date: May 19, 2016
    Applicants: DEVELOPMENT CENTER FOR BIOTECHNOLOGY, DCB-USA LLC
    Inventors: Mann-Yan KUO, Ying-Shuan LEE, Paonien CHEN, Li Jung CHEN, Yann Yu LU, Yi-Ting HUANG, Hung-Yi HSU, Ping-Kuei TSAI
  • Pyrimidine compounds as mTOR and PI3K inhibitors
    Patent number: 9315491
    Abstract: The present invention relates to pyrimidine compounds of formula (I): which are useful in treating mTOR kinase- or PI3K kinase-related diseases.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: April 19, 2016
    Assignees: DEVELOPMENT CENTER FOR BIOTECHNOLOGY, DCB-USA LLC
    Inventors: Mann-Yan Kuo, Ying-Shuan Lee, Paonien Chen, Li Jung Chen, Yann Yu Lu, Yi-Ting Huang, Hung-Yi Hsu, Ping-Kuei Tsai
  • NOVEL PYRIMIDINE COMPOUNDS AS mTOR AND PI3K INHIBITORS
    Publication number: 20140178360
    Abstract: The present invention relates to pyrimidine compounds of formula (I): which are useful in treating mTOR kinase- or PI3K kinase-related diseases.
    Type: Application
    Filed: February 27, 2014
    Publication date: June 26, 2014
    Applicants: DCB-USA LLC, DEVELOPMENT CENTER FOR BIOTECHNOLOGY
    Inventors: Mann-Yan KUO, Ying-Shuan Lee, Paonien Chen, Li Jung Chen, Yann Yu Lu, Yi-Ting Huang, Hung-Yi Hsu, Ping-Kuei Tsai
  • NOVEL PYRIMIDINE COMPOUNDS AS mTOR AND PI3K INHIBITORS
    Publication number: 20120288492
    Abstract: The present invention relates to pyrimidine compounds of formula (I): which are useful in treating mTOR kinase- or PI3K kinase-related diseases.
    Type: Application
    Filed: December 27, 2010
    Publication date: November 15, 2012
    Applicants: DCB-USA LLC, DEVELOPMENT CENTER FOR BIOTECHNOLOGY
    Inventors: Mann-Yan Kuo, Ying-Shuan Lee, Paonien Chen, Li Jung Chen, Yann Yu Lu, Yi-Ting Huang, Hung-Yi Hsu, Ping-Kuei Tsai
  • PROTEIN KINASE INHIBITORS
    Publication number: 20090163494
    Abstract: This invention relates to selenophene compounds of formula (I) shown below: Each variable in formula (I) is defined in the specification. These compounds can be used to treat cancer.
    Type: Application
    Filed: December 19, 2007
    Publication date: June 25, 2009
    Inventors: Pao-Chiung Hong, Li-Jung Chen, Yann-Yu Lu, Tzu-Yun Lai, Huei-Ru Yang, Yi-Feng Kao, Kuei-Tai Lai, Young-Sun Lin
  • Preparation of amides and quinazoline derivatives
    Patent number: 6313293
    Abstract: The present invention relates to a process for the preparation of amides, comprising reacting amines with carboxylic acids in the presence of silicon amines. The present invention further relates to a process for the preparation of quinazoline derivatives, comprising reacting amines with carboxylic acids in the presence of silicon amines to obtain amides and contacting the resultant amides with quinazoline.
    Type: Grant
    Filed: March 1, 2000
    Date of Patent: November 6, 2001
    Assignee: Development Center for Biotechnology
    Inventors: Wen-Chih Chou, Ming-Chen Chou, Yann-Yu Lu, Shyh-Fong Chen