Patents by Inventor Yanni Zhang
Yanni Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12294573Abstract: An approach for optimizing security token exchange. The approach receives a first request from a client. The approach extracts a first security token and an API reference. The approach validates the first security token. If the security token is valid, then the approach, calls the API and retrieves a second security token, embeds the second security token in the API and sends a second request with a third security token and the reference to the API to another application in a different domain.Type: GrantFiled: December 10, 2021Date of Patent: May 6, 2025Assignee: International Business Machines CorporationInventors: Chunlong Liang, Jose Angel Rodriguez, James T. Mulvey, Jose I. Ortiz, Xiaoyan Yanni Zhang
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Publication number: 20250093364Abstract: Provided are methods for determining the amount of thyroglobulin in a sample using various purification steps followed by mass spectrometry. The methods generally involve adding an internal standard to the test sample; digesting thyroglobulin from the test sample and the internal standard to form thyroglobulin peptides; purifying the thyroglobulin peptides; ionizing the thyroglobulin peptides to generate one or more ions detectable by mass spectrometry; quantifying the amount of the one or more ions by mass spectrometry, wherein the one or more ions comprise an ion having a mass/charge ratio of 541.3±0.5, 612.3±0.5, 636.4±0.5, 726.4±0.5, 797.4±0.5, 912.4±0.5, and/or 1059.5±0.5; and relating the amount of the one or more ions to the amount of thyroglobulin in the test sample.Type: ApplicationFiled: October 25, 2024Publication date: March 20, 2025Inventors: Yanni Zhang, Nigel J. Clarke, Richard E. Reitz
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Publication number: 20240400989Abstract: Disclosed is a method for promoting immune cell proliferation. The method comprises the following step: upregulating the expression of low-density lipoprotein receptor-related proteins or fragments thereof in immune cells.Type: ApplicationFiled: May 1, 2024Publication date: December 5, 2024Applicant: ORICELL THERAPEUTICS CO., LTD.Inventors: Hao GUO, Ruirong YI, Yanni ZHANG, Siye CHEN, Xiaowen HE
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Patent number: 12140597Abstract: Provided are methods for determining the amount of thyroglobulin in a sample using various purification steps followed by mass spectrometry. The methods generally involve purifying thyroglobulin in a test sample, digesting thyroglobulin to form peptide T129, purifying peptide T129, ionizing peptide T129, detecting the amount of peptide T129 ion generated, and relating the amount of peptide T129 ion to the amount of thyroglobulin originally present in the sample.Type: GrantFiled: December 29, 2022Date of Patent: November 12, 2024Assignee: Quest Diagnostics Investments IncorporatedInventors: Yanni Zhang, Nigel J. Clarke, Richard E Reitz
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Publication number: 20240267209Abstract: Mechanisms are provided for salted password protection of computing resources. An entity identifier and password for authenticating an entity to access a protected computing resource are received. A salt value is generated as a random value that is combined with the password to generate a salted password. A hash value is generated based on a hash function and the salted password as an input to the hash function. Based on the password, an encryption key is generated for encrypting the salt value. The salt value is encrypted based on the encryption key and an encryption algorithm to generate an encrypted salt value. The entity identifier, hash value, and encrypted salt value are stored in a secured database for later retrieval to validate subsequent access requests specifying the entity identifier.Type: ApplicationFiled: February 8, 2023Publication date: August 8, 2024Inventors: Chunlong Liang, James T. Mulvey, Jose Angel Rodriguez, Jose I. Ortiz, Xiaoyan Yanni Zhang
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Publication number: 20240267210Abstract: Mechanisms are provided for salted password protection of computing resources. An entity identifier and password for authenticating an entity to access a protected computing resource are received and a client salt value is generated by a password management engine of a client computing device. A server salt value is generated as a random value that is combined with the client salt value to generate a combined salt value. The combined salt value is combined with the password to generate a combined salted password. A hash value is generated based on a hash function and the combined salted password as an input to the hash function, and the server salt value is encrypted based on an encryption key and an encryption algorithm to generate an encrypted server salt value. The entity identifier, hash value, and encrypted server salt value are stored in a secured database for later validation of access requests.Type: ApplicationFiled: February 8, 2023Publication date: August 8, 2024Inventors: Chunlong Liang, James T. Mulvey, Jose Angel Rodriguez, Jose I. Ortiz, Xiaoyan Yanni Zhang
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Publication number: 20230393144Abstract: Provided herein are methods of mitigating (such as eliminating) interference in a serological assay caused by a therapeutic anti-CD47 antibody. Also provided are anti-idiotypic antibodies for use in such methods. Also provided are methods of transfusing donor blood to a subject who is under treatment with a therapeutic anti-CD47 antibody.Type: ApplicationFiled: October 14, 2021Publication date: December 7, 2023Inventors: Wei Cao, Zhengyi Wang, Yanni Zhang, Bingshi Guo
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Publication number: 20230236200Abstract: Provided are methods for determining the amount of thyroglobulin in a sample using various purification steps followed by mass spectrometry. The methods generally involve purifying thyroglobulin in a test sample, digesting thyroglobulin to form peptide T129, purifying peptide T129, ionizing peptide T129, detecting the amount of peptide T129 ion generated, and relating the amount of peptide T129 ion to the amount of thyroglobulin originally present in the sample.Type: ApplicationFiled: December 29, 2022Publication date: July 27, 2023Inventors: Yanni Zhang, Nigel J. Clarke, Richard E Reitz
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Publication number: 20230188515Abstract: An approach for optimizing security token exchange. The approach receives a first request from a client. The approach extracts a first security token and an API reference. The approach validates the first security token. If the security token is valid, then the approach, calls the API and retrieves a second security token, embeds the second security token in the API and sends a second request with a third security token and the reference to the API to another application in a different domain.Type: ApplicationFiled: December 10, 2021Publication date: June 15, 2023Inventors: Chunlong Liang, Jose Angel Rodriguez, James T. Mulvey, Jose I. Ortiz, Xiaoyan Yanni Zhang
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Patent number: 11543415Abstract: Provided are methods for determining the amount of thyroglobulin in a sample using various purification steps followed by mass spectrometry. The methods generally involve purifying thyroglobulin in a test sample, digesting thyroglobulin to form peptide T129, purifying peptide T129, ionizing peptide T129, detecting the amount of peptide T129 ion generated, and relating the amount of peptide T129 ion to the amount of thyroglobulin originally present in the sample.Type: GrantFiled: June 3, 2019Date of Patent: January 3, 2023Assignee: Quest Diagnostics Investments IncorporatedInventors: Yanni Zhang, Nigel J. Clarke, Richard E Reitz
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Patent number: 11250046Abstract: An image viewing method and a mobile terminal are provided. The method includes: detecting whether a viewing instruction of a user for a display identifier on a target position is received, where the display identifier is a display identifier of a target image selected by the user from an image selection interface; displaying the target image corresponding to the display identifier, in a case that the viewing instruction is received; and jumping to a position where the target image is located in the image selection interface.Type: GrantFiled: October 19, 2018Date of Patent: February 15, 2022Assignee: VIVO MOBILE COMMUNICATION CO., LTD.Inventor: Yanni Zhang
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Patent number: 10925498Abstract: An ambient light filter configured to filter ambient light noises from an optical current that is at least partially caused by an optical pulse sequence emitted by a light emitting device, can include: a sample and detection circuit configured to sample the optical current and to obtain a current component in a first mode, and to remove the current component from the optical current and to generate a detection signal in a second mode; a current amplifier configured to receive the detection signal, and to generate an amplified current signal; and a control circuit configured to switch the sample and detection circuit between the first and second modes, where the control circuit switches the sample and detection circuit to the first mode in at least one optical pulse gap, and switches the sample and detection circuit to the second mode when a next optical pulse arrives.Type: GrantFiled: April 1, 2017Date of Patent: February 23, 2021Assignee: Silergy Semiconductor Technology (Hangzhou) LTDInventors: Huisen He, Baoyu Zhang, Yanni Zhang, Lili Shao
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Publication number: 20200327158Abstract: An image viewing method and a mobile terminal are provided. The method includes: detecting whether a viewing instruction of a user for a display identifier on a target position is received, where the display identifier is a display identifier of a target image selected by the user from an image selection interface; displaying the target image corresponding to the display identifier, in a case that the viewing instruction is received; and jumping to a position where the target image is located in the image selection interface.Type: ApplicationFiled: October 19, 2018Publication date: October 15, 2020Applicant: VIVO MOBILE COMMUNICATION CO., LTD.Inventor: Yanni ZHANG
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Patent number: 10718779Abstract: Provided are methods for determining the amount of thyroglobulin in a sample using various purification steps followed by mass spectrometry. The methods generally involve purifying thyroglobulin in a test sample, digesting thyroglobulin to form peptide T129, purifying peptide T129, ionizing peptide T129, detecting the amount of peptide T129 ion generated, and relating the amount of peptide T129 ion to the amount of thyroglobulin originally present in the sample.Type: GrantFiled: January 28, 2019Date of Patent: July 21, 2020Assignee: Quest Diagnostics Investments IncorporatedInventors: Yanni Zhang, Nigel J. Clarke, Richard E. Reitz
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Publication number: 20190317109Abstract: Provided are methods for determining the amount of thyroglobulin in a sample using various purification steps followed by mass spectrometry. The methods generally involve purifying thyroglobulin in a test sample, digesting thyroglobulin to form peptide T129, purifying peptide T129, ionizing peptide T129, detecting the amount of peptide T129 ion generated, and relating the amount of peptide T129 ion to the amount of thyroglobulin originally present in the sample.Type: ApplicationFiled: June 3, 2019Publication date: October 17, 2019Inventors: Yanni Zhang, Nigel J. Clarke, Richard E Reitz
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Patent number: 10349846Abstract: A photoelectric sensor can include: a lighting element configured to generate a first optical signal, where a second optical signal is generated by reflection of the first optical signal when emitting an object; a driving circuit configured to drive the lighting element; a photoelectric conversion circuit configured to generate a first optical current in accordance with the second optical signal; and a programmable current amplifier circuit configured to sample and hold the first optical current when the lighting element is in operation, and to generate a second optical current when the lighting element is out of operation in one detection period, where the second optical current lasts for at least one working period in the detection period, and where the second optical current represents the first optical current.Type: GrantFiled: April 1, 2017Date of Patent: July 16, 2019Assignee: Silergy Semiconductor Technology (Hangzhou) LTDInventors: Baoyu Zhang, Huisen He, Lili Shao, Yanni Zhang
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Patent number: 10309971Abstract: Provided are methods for determining the amount of thyroglobulin in a sample using various purification steps followed by mass spectrometry. The methods generally involve purifying thyroglobulin in a test sample, digesting thyroglobulin to form peptide T129, purifying peptide T129, ionizing peptide T129, detecting the amount of peptide T129 ion generated, and relating the amount of peptide T129 ion to the amount of thyroglobulin originally present in the sample.Type: GrantFiled: June 1, 2015Date of Patent: June 4, 2019Assignee: Quest Diagnostics Investments IncorporatedInventors: Yanni Zhang, Nigel J. Clarke, Richard E. Reitz
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Publication number: 20190145984Abstract: Provided are methods for determining the amount of thyroglobulin in a sample using various purification steps followed by mass spectrometry. The methods generally involve purifying thyroglobulin in a test sample, digesting thyroglobulin to form peptide T129, purifying peptide T129, ionizing peptide T129, detecting the amount of peptide T129 ion generated, and relating the amount of peptide T129 ion to the amount of thyroglobulin originally present in the sample.Type: ApplicationFiled: January 28, 2019Publication date: May 16, 2019Inventors: Yanni Zhang, Nigel J. Clarke, Richard E. Reitz
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Patent number: 10191064Abstract: Provided are methods for determining the amount of thyroglobulin in a sample using various purification steps followed by mass spectrometry. The methods generally involve purifying thyroglobulin in a test sample, digesting thyroglobulin to form peptide T129, purifying peptide T129, ionizing peptide T129, detecting the amount of peptide T129 ion generated, and relating the amount of peptide T129 ion to the amount of thyroglobulin originally present in the sample.Type: GrantFiled: February 27, 2018Date of Patent: January 29, 2019Assignee: Quest Diagnostics Investments IncorporatedInventors: Yanni Zhang, Nigel J. Clarke, Richard E. Reitz
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Patent number: 10121815Abstract: A photo detector can include: a light emitting device configured to emit light; a driving circuit configured to drive the light emitting device; a photo-electric conversion circuit configured to generate an optical current signal according to an optical signal; an isolation circuit configured to transmit the optical current signal in an isolated manner; an ambient light filter configured to filter a current component of the optical current signal corresponding to an ambient light, and to generate a clean optical current signal; a current amplification circuit configured to amplify the clean optical current signal, and to generate an amplified optical current signal; (vii) an analog-to-digital converter configured to convert the amplified optical current signal to a digital signal; and a control circuit configured to output an optical detection signal according to the digital signal.Type: GrantFiled: April 1, 2017Date of Patent: November 6, 2018Assignee: Silergy Semiconductor Technology (Hangzhou) LTDInventors: Lili Shao, Huisen He, Baoyu Zhang, Yanni Zhang