Patents by Inventor Yannick Benedetti
Yannick Benedetti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20150210729Abstract: The patent application relates to compounds of formula (I) below: to a process for preparing them and to the therapeutic use thereof.Type: ApplicationFiled: March 16, 2015Publication date: July 30, 2015Inventors: Nicolas BAURIN, Yannick BENEDETTI, Emmanuel BOULEY, Jidong ZHANG
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Patent number: 7994161Abstract: The present invention relates to 2-alkoxy-3,4,5-trihydroxyalkylamide derivatives, to pharmaceutical compositions comprising such compounds, to methods of treatment comprising administering such compounds, to processes for the preparation of such compounds, and to intermediate precursors to such compounds.Type: GrantFiled: November 10, 2008Date of Patent: August 9, 2011Assignee: Sanofi-AventisInventors: Jidong Zhang, Yannick Benedetti, Alain Commerçon
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Patent number: 7960373Abstract: The present invention relates to 2-alkoxy-3,4,5-trihydroxyalkylamide benzothiazepine compounds, to pharmaceutical compositions comprising such compounds, to methods of treatment comprising administering such compounds, to processes for the preparation of such compounds and to intermediate precursors to such compounds.Type: GrantFiled: November 10, 2008Date of Patent: June 14, 2011Assignee: Sanofi-AventisInventors: Jidong Zhang, Yannick Benedetti, Frederico Nardi, Alain Commerçon
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Patent number: 7632952Abstract: The invention especially relates to novel chemical compounds, especially novel benzothiazole derivatives, to compositions containing said compounds, and to the use thereof as medicaments.Type: GrantFiled: September 29, 2006Date of Patent: December 15, 2009Assignee: Aventis Pharma S.A.Inventors: Stéphanie Deprets, Anke Steinmetz, Odile Angouillant-Boniface, Daniel Bezard, Jidong Zhang, Yannick Benedetti, François Clerc
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Patent number: 7517881Abstract: The invention relates to triazine derivatives of general formula (I): Wherein R1, R2 and R3 are as defined herein. The invention also relates to a method for preparing these triazine derivatives and to the therapeutic application thereof.Type: GrantFiled: October 9, 2007Date of Patent: April 14, 2009Assignee: Aventis Pharma S.A.Inventors: Yannick Benedetti, Andrees Bohme, Arielle Genevois-Borella, Gaetan Touyer, Jidong Zhang
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Publication number: 20090093459Abstract: The present invention relates to 2-alkoxy-3,4,5-trihydroxyalkylamide benzothiazepine compounds, to pharmaceutical compositions comprising such compounds, to methods of treatment comprising administering such compounds, to processes for the preparation of such compounds and to intermediate precursors to such compounds.Type: ApplicationFiled: November 10, 2008Publication date: April 9, 2009Applicant: SANOFI-AVENTISInventors: Jidong ZHANG, Yannick BENEDETTI, Frederico NARDI, Alain COMMERCON
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Publication number: 20090075971Abstract: The present invention relates to 2-alkoxy-3,4,5-trihydroxyalkylamide derivatives, to pharmaceutical compositions comprising such compounds, to methods of treatment comprising administering such compounds, to processes for the preparation of such compounds, and to intermediate precursors to such compounds.Type: ApplicationFiled: November 10, 2008Publication date: March 19, 2009Applicant: SANOFI-AVENTISInventors: Jidong Zhang, Yannick Benedetti, Alain Commercon
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Publication number: 20080096891Abstract: The invention relates to triazine derivatives of general formula (I): Wherein R1, R2 and R3 are as defined herein. The invention also relates to a method for preparing these triazine derivatives and to the therapeutic application thereof.Type: ApplicationFiled: October 9, 2007Publication date: April 24, 2008Applicant: AVENTIS PHARMA S.A.Inventors: Yannick BENEDETTI, Andrees BOHME, Arielle GENEVOIS-BORELLA, Gaetan TOUYER, Jidong ZHANG
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Publication number: 20070093488Abstract: The invention especially relates to novel chemical compounds, especially novel benzothiazole derivatives, to compositions containing said compounds, and to the use thereof as medicaments.Type: ApplicationFiled: September 29, 2006Publication date: April 26, 2007Applicant: AVENTIS PHARMA S.A.Inventors: Stephanie Deprets, Anke Steinmetz, Odile Angouillant-Boniface, Daniel Bezard, Jidong Zhang, Yannick Benedetti, Francois Clerc
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Publication number: 20030187267Abstract: The invention concerns compounds of formula (I) wherein: p=1 or 2; X, X1 and X2 represent N or CH═; R1, R2, R3, R4, R5 and R6 represent a hydrogen atom, a halogen atom, alkyl, O-alkyl, S—(O)nalkyl, alkenyl, O-alkenyl, S—(O)nalkenyl, alkynyl, O-alkynyl, S—(O)nalkynyl; n=0, 1 or 2, or NO2, NH2 or C═N or R1, R2, R3 or R5, R6 form a cycle, or R4A can be cycloalkyl, heterocycle, aryl, O-aryl or oxygenated or nitrogenated chain; R7 represents H, OH, SO3H or OPO(OH)2; A and B=hydrogen or oxygenated or nitrogenated chain; C and D=hydrogen, halogen or alkyl or together form with the carbons bearing them a cycle. The compounds of formula (I) have antifungal properties.Type: ApplicationFiled: December 5, 2002Publication date: October 2, 2003Inventors: Didier Babin, Yannick Benedetti, Fabienne Chatreaux, John Bernard Weston
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Patent number: 6022965Abstract: An isomerization method wherein a compound of formula ##STR1## wherein X and y together form a 3-oxo radical, or X is a hydrogen atom and Y is either a radical a ##STR2## where R.sub.2 is OH or O-acyl, or an O-alkyl or NH.sub.2 radical; R.sub.1 is a hydrogen atom or a methyl radical; Z is hydrogen or an acyl radical; and R is a hydrogen atom, an NH.sub.2 radical or a (CH.sub.2).sub.n Ar, NH(CH.sub.2).sub.n Ar or N.dbd.CH(CH.sub.2).sub.n Ar radical, in the form of a 10.alpha. isomer or a mixture of 10.alpha. and 10.beta. isomers, is exposed to a basic agent to give the corresponding compound of formula I in which the 10-methyl radical is in the .beta. position.Type: GrantFiled: November 11, 1998Date of Patent: February 8, 2000Assignee: Hoechst Marion RousselInventors: Yannick Benedetti, Jacques Lagouardat, Jacques Scholl
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Patent number: 5770579Abstract: Compounds of the formula ##STR1## wherein X and X' form C.dbd.O or C.dbd.NOR, R is selected from the group consisting of hydrogen, heterocycle, alkyl, alkenyl, alkynyl, all optionally substituted, ##STR2## R.sub.a and R.sub.b are hydrogen or a hydrocarbon group or form together with the nitrogen a heterocycle, or with A forms a 9-N, 11-O ring, and X' is hydrogen, --Y and Y' have the same definition as X and X', b is hydrogen or OR.sub.4, R.sub.4 is hydrogen or forms together with A a carbonate or a carbamate, A forms with C a double bond or A is OR'.sub.4, R'.sub.4 is hydrogen or forms together with B a carbonate or ##STR3## R.sub.2 is alkyl or --CONH.sub.2, --CONHCOR.sub.11 or --CONHSO.sub.2 R.sub.11, R.sub.11 is a hydrocarbon up to 18 carbon atoms, R.sub.3 is hydrogen, ##STR4## and Z is hydrogen or a carboxylic acid remainder and their non-toxic, pharmaceutically acceptable acid addition salts, their preparation and intermediates useful as antibiotics.Type: GrantFiled: January 25, 1995Date of Patent: June 23, 1998Assignee: Roussel UclafInventors: Constantin Agouridas, Yannick Benedetti, Jean-Fran.cedilla.ois Chantot, Alexis Denis, Claude Fromentin, Odile Le Martret
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Patent number: 5760233Abstract: A compound selected from the group consisting of a compound of the formula ##STR1## wherein R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen and an optionally unsaturated hydrocarbon of up to 24 carbon atoms optionally interrupted by at least one heteroatom selected from the group consisting of oxygen, sulfur and nitrogen and optionally having at least one functional group or taken together form ##STR2## and R'.sub.1 and R'.sub.Type: GrantFiled: February 25, 1997Date of Patent: June 2, 1998Assignee: Roussel UclafInventors: Constantin Agouridas, Yannick Benedetti, Jean-Francois Chantot, Alexis Denis, Odile Le Martret
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Patent number: 5656607Abstract: A compound selected from the group consisting of a compound of the formula ##STR1## wherein R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen and an optionally unsaturated hydrocarbon of up to 24 carbon atoms optionally interrupted by at least one heteroatom selected from the group consisting of oxygen, sulfur and nitrogen and optionally having at least one functional group or taken together form ##STR2## and R'.sub.1 and R'.sub.Type: GrantFiled: March 31, 1995Date of Patent: August 12, 1997Assignee: Roussel UclafInventors: Constantin Agouridas, Yannick Benedetti, Jean-Francois Chantot, Alexis Denis, Odile Le Martret
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Patent number: 5561118Abstract: Compounds of the formula ##STR1## wherein X and X' form C.dbd.O or C.dbd.NOR, R is selected from the group consisting of hydrogen, heterocycle, alkyl, alkenyl, alkynyl, all optionally substituted, or X is ##STR2## R.sub.a and R.sub.b are hydrogen or a hydrocarbon group or form together with the nitrogen a heterocycle, or with A forms a 9-N, 11-0 ring, and X' is hydrogen, --Y and Y' have the same definition as X and X', B is hydrogen or OR.sub.4, R.sub.4 is hydrogen or forms together with A a carbonate or a carbamate, A forms with C a double bond or A is OR'.sub.4, R'.sub.4 is hydrogen or forms together with B a carbonate or A is ##STR3## R.sub.2 is alkyl or --CONH.sub.2, --CONHCOR.sub.11 or --CONHSO.sub.2 R.sub.11, R.sub.11 is a hydrocarbon up to 18 carbon atoms, R.sub.3 is hydrogen, ##STR4## and Z is hydrogen or a carboxylic acid remainder and their non-toxic, pharmaceutically acceptable acid addition salts, their preparation and intermediates useful as antibiotics.Type: GrantFiled: March 31, 1994Date of Patent: October 1, 1996Assignee: Roussel UclafInventors: Constantin Agouridas, Yannick Benedetti, Jean-Francois Chantot, Alexis Denis, Claude Fromentin, Odile Le Martret
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Patent number: 5444051Abstract: Compounds of the formula ##STR1## wherein X and X' form C.dbd.O or C.dbd.NOR, R is selected from the group consisting of hydrogen, heterocycle, alkyl, alkenyl, alkynyl, all optionally substituted,or X is ##STR2## R.sub.a and R.sub.b are hydrogen or a hydrocarbon group or form together with the nitrogen a heterocycle, or with A forms a 9-N, 11-O ring, and X' is hydrogen, --Y and Y' have the same definition as X and X', B is hydrogen or OR.sub.4, R.sub.4 is hydrogen or forms together with A a carbonate or a carbamate, A forms with C a double bond or A is OR'.sub.4, R'.sub.4 is hydrogen or forms together with B a carbonate or ##STR3## R.sub.2 is alkyl or --CONH.sub.2, --CONHCOR.sub.11 or --CONHSO.sub.2 R.sub.11, R.sub.11 is a hydrocarbon up to 18 carbon atoms, R.sub.3 is hydrogen, ##STR4## and Z is hydrogen or a carboxylic acid remainder and their non-toxic, pharmaceutically acceptable acid addition salts, their preparation and intermediates useful as antibiotics.Type: GrantFiled: June 28, 1993Date of Patent: August 22, 1995Assignee: Roussel UCLAFInventors: Constantin Agouridas, Yannick Benedetti, Jean-Francois Chantot, Alexis Denis, Claude Fromentin, Odile Le Martret
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Patent number: 5439889Abstract: All possible stereoisomeric forms and mixtures thereof of a compound of the formula ##STR1## wherein the substituents are as defined in the specification and their non-toxic, pharmaceutically acceptable acid addition salts having antibiotic properties.Type: GrantFiled: March 7, 1994Date of Patent: August 8, 1995Assignee: Roussel UclafInventors: Constantin Agouridas, Yannick Benedetti, Jean-Francois Chantot, Alexis Denis