Patents by Inventor Yannick Fillon

Yannick Fillon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OLIGONUCLEOTIDES, REAGENTS, AND PREPARATION THEREOF
    Publication number: 20230406878
    Abstract: The present disclosure describes novel reagents and processes for preparing oligonucleotides, which have two or more nucleotides. In one embodiment, the reagent is represented by Formula I? or B.
    Type: Application
    Filed: November 10, 2021
    Publication date: December 21, 2023
    Inventors: Wuming Yan, Xuan Zhou, Xianglin Shi, Firoz Antia, William F. Kiesman, Yannick Fillon
  • CONVERGENT LIQUID PHASE SYNTHESES OF OLIGONUCLEOTIDES
    Publication number: 20220348602
    Abstract: The present disclosure describes a convergent liquid phase process for manufacturing oligonucleotides by coupling two or more oligonucleotide fragments, each of which have two or more nucleotides. Also provided by the present disclosure are reaction steps involved the convergent liquid phase process.
    Type: Application
    Filed: May 8, 2020
    Publication date: November 3, 2022
    Inventors: Xianglin Shi, William F. Kiesman, Firoz Antia, Yannick Fillon, Xuan Zhou, Wuming Yan, Hong Jiang, Hien Nguyen, Robert S. Gronke, Taisuke Ichimaru, Takuya Hamagaki, Daisuke Takahashi
  • Synthesis of thiolated oligonucleotides without a capping step
    Patent number: 11142545
    Abstract: The invention herein describes a solid-phase synthetic method for preparing thiolated oligonucleotides without needing a capping step. The methods of the invention comprises repetition of a three-reaction per cycle, namely detritylation, coupling and sulfurization, without a capping step. In some embodiments, the synthetic methods of the present invention can be used for preparing an anti-sense oligonucleotide.
    Type: Grant
    Filed: June 22, 2017
    Date of Patent: October 12, 2021
    Assignee: BIOGEN MA INC.
    Inventors: Xianglin Shi, Jimin Yang, William F. Kiesman, Yannick Fillon
  • SYNTHESIS OF THIOLATED OLIGONUCLEOTIDES WITHOUT A CAPPING STEP
    Publication number: 20190161513
    Abstract: The invention herein describes a synthetic method for preparing thiolated oligonucleotides without needing a capping step, as the sulfurization agent caps the unreacted 5?-OH groups.
    Type: Application
    Filed: June 22, 2017
    Publication date: May 30, 2019
    Inventors: Xianglin Shi, Jimin Yang, William F. Kiesman, Yannick Fillon