Abstract: In some embodiments, a method receives a plurality of video segments of a video using a plurality of computing instances and measures data received for the plurality of computing instances during a time window. A video segment for a computing instance in the plurality of computing instances is not fully downloaded during the time window. The method calculates a video delivery metric for the plurality of computing instances based on the data received and calculates an evaluation measurement based on the video delivery metric. The evaluation measurement is used to control an addition or a termination of a computing instance.

Abstract: Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.

Abstract: Compounds of general formula (A) can be used for treating ATR kinase-mediated diseases, for example, hyperplastic diseases such as cancers. Also provided are a pharmaceutical composition of the compounds of general formula (A), a use of the pharmaceutical composition for treating the ATR kinase-mediated diseases and a preparation method for the pharmaceutical composition.

Abstract: The application describes fused heterocycle derivative compounds, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment of diseases associated with HBV infection.

Abstract: The application describes dihydropyrimidine derivatives which are useful in the treatment or prevention of HBV infection or of HBV-induced diseases, more particularly of HBV chronic infection or of diseases induced by HBV chronic infection, as well as pharmaceutical or medical applications thereof.

Abstract: Provided herein are dihydropyrimidine derivatives which are useful in the treatment or prevention of HBV infection or of HBV-induced diseases, more particularly of HBV chronic infection or of diseases induced by HBV chronic infection, as well as pharmaceutical or medical applications thereof.

Abstract: Provided herein are dihydropyrimidine derivatives which are useful in the treatment or prevention of HBV infection or of HBV-induced diseases, more particularly of HBV chronic infection or of diseases induced by HBV chronic infection, as well as pharmaceutical or medical applications thereof.

Abstract: Disclosed is an application of Epigallocatechin Gallate (EGCG) or a compound synthesized with it as a lead compound in combination with one or more tyrosine kinase inhibitors in preparation of a cancer treatment drug, herein the cancer is an Epidermal Growth Factor Receptor (EGFR) wild-type tumor. This combined use may significantly inhibit the growth of the EGFR wild-type tumor, and reduce the toxic and side effects of an anticancer drug.

Abstract: Systems and methods include, responsive to a request for capacity change of X channels, X is an integer >1, on an optical section (14) and at an Optical Add/Drop Multiplexer (OADM) node (12) in an optical network (10), dividing optical spectrum on the optical section into M slots, M is an integer >1, such that the capacity change of X channels takes a maximum of N steps, N is an integer >1; and performing the capacity change of X channels in up to the N steps in an interleaved manner that changes a subset of the X channels in each of the N steps. For each step, the performing can include a maximum of M/N slots of the M slots with spacing between each of the M/N slots not used for the capacity change in a corresponding step. The spacing can be f, (N+f), (2N+f), . . . , M over the optical spectrum, where f is each step, f=1, 2, . . . , N.

Abstract: Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.

Abstract: The application describes dihydropyrimidine derivatives which are useful in the treatment or prevention of HBV infection or of HBV-induced diseases, more particularly of HBV chronic infection or of diseases induced by HBV chronic infection, as well as pharmaceutical or medical applications thereof.

Abstract: Systems and methods are provided for controlling one or more optical amplifiers of a C+L band photonic line system of a telecommunications network in which C-band signals and L-band signals may be transmitted. In one implementation, a control device may include a processing device and a memory device configured to store a traffic managing module for controlling C-band and the L-band traffic in the photonic line system. The traffic managing module, when executed, may be configured to cause the processing device to calculate a gain correction profile based on a difference between a saved baseline transmission profile and a measured transmission profile of a surviving band of a photonic line system when another band of the photonic line system is missing or impacted. The traffic managing module is configured to apply the gain correction profile to a respective optical amplifier of the photonic line system to compensate for the difference.

Abstract: The invention provides compounds of the formula: (A), pharmaceutically acceptable salts, pharmaceutical compositions thereof and methods of using these compounds, salts, or compositions to treat hyperphosphatemia, chronic kidney disease, and/or the cardiovascular disease associated with chronic kidney disease.

Abstract: Systems, methods, and non-transitory computer-readable media are provided for performing channel swapping techniques for swapping bundles of optical channels in an optical network, such as a C+L band system, based on frequency band sensitivity. In one embodiment, a method includes swapping a first group of channels or first portion of spectrum in a more-sensitive frequency band with a first set of replacement channels or first portion of replacement spectrum using a first swapping technique. The method also includes swapping a second group of channels or second portion of spectrum in a less-sensitive frequency band with a second set of replacement channels or second portion of replacement spectrum using a second swapping technique that is different from the first swapping technique. The first and second swapping techniques are based at least in part on the number of channels or portion of spectrum that can be swapped at any given time instance.

Abstract: Systems and methods include, responsive to a request for capacity change of X channels, X is an integer>1, on an optical section and at an Optical Add/Drop Multiplexer (OADM) node in an optical network, dividing optical spectrum on the optical section into M slots, M is an integer>1, such that the capacity change of X channels takes a maximum of N steps, N is an integer>1; and performing the capacity change of X channels in up to the N steps in an interleaved manner that changes a subset of the X channels in each of the N steps. For each step, the performing can include a maximum of M/N slots of the M slots with spacing between each of the M/N slots not used for the capacity change in a corresponding step. The spacing can be f, (N+f), (2N+f), . . . , M over the optical spectrum, where f is each step, f=1, 2, . . . , N.

Abstract: The application describes dihydropyrimidine derivatives which are useful in the treatment or prevention of HBV infection or of HBV-induced diseases, more particularly of HBV chronic infection or of diseases induced by HBV chronic infection, as well as pharmaceutical or medical applications thereof.

Abstract: The invention provides compounds of the formula: (A), pharmaceutically acceptable salts, pharmaceutical compositions thereof and methods of using these compounds, salts, or compositions to treat hyperphosphatemia, chronic kidney disease, and/or the cardiovascular disease associated with chronic kidney disease.

Abstract: A method and device for modeling a long-time-scale photovoltaic output time sequence are provided. The method includes that: historical data of a photovoltaic power station is acquired, and a photovoltaic output with a time length of one year and a time resolution of 15 mins is selected (101); weather types of days corresponding to the photovoltaic output are acquired from a weather station (102), and probabilities of transfer between each type of weather are calculated respectively (103); and a simulated time sequence of the photovoltaic output within a preset time scale is generated (104), and its validity is verified (105). By the method, annual and monthly photovoltaic output simulated time sequences consistent with a random fluctuation rule of a photovoltaic time sequence may be acquired according to different requirements to provide a favorable condition and a data support for analog simulation of time sequence production including massive new energy.

Abstract: Provided is an online body size measurement system, comprising a user information upload module (1), an image processing module (2), a management module (4) and a data storage module (3). The user information upload module (1) uploads the user information containing image information and height information to the image processing module (2). The image processing module (2) performs tracing on the image information and matches the traced 3D lattice information with the height information, so as to generate user size information, the user size information being stored in the data storage module (3) connected to the management module (4), and the user size information containing a unique secret order for identifying the user.

Abstract: A method and device for modeling a long-time-scale photovoltaic output time sequence are provided. The method includes that: historical data of a photovoltaic power station is acquired, and a photovoltaic output with a time length of one year and a time resolution of 15 mins is selected (101); weather types of days corresponding to the photovoltaic output are acquired from a weather station (102), and probabilities of transfer between each type of weather are calculated respectively (103); and a simulated time sequence of the photovoltaic output within a preset time scale is generated (104), and its validity is verified (105). By the method, annual and monthly photovoltaic output simulated time sequences consistent with a random fluctuation rule of a photovoltaic time sequence may be acquired according to different requirements to provide a favorable condition and a data support for analogue simulation of time sequence production including massive new energy.