Patents by Inventor Yanping Yu
Yanping Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190265564Abstract: The present disclosure provides an array substrate and a display panel containing the array substrate. The array substrate includes a plurality of pixel regions, and pixel electrodes and thin film transistors one-to-one corresponding thereto. Each pixel electrode includes a pixel sub-electrode and an electrode connecting structure disposed in a corresponding pixel region, and a drain electrode of each thin film transistor is electrically connected to a corresponding pixel sub-electrode. The plurality of pixel regions includes at least one first-color pixel region and at least one second-color pixel region alternately arranged along a first direction and at least one third-color pixel region and at least one highlight pixel region alternately arranged along a first direction. A drain electrode is electrically connected to a pixel sub-electrode disposed in one of the at least one third-color pixel region is disposed in a highlight pixel region adjacent to the third-color pixel region.Type: ApplicationFiled: June 4, 2018Publication date: August 29, 2019Inventors: Mingjuan LI, Ling WU, Yanping YU, Ankai LING, Boping SHEN
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Publication number: 20190235324Abstract: An array substrate, a display panel, and a display device are provided. The array substrate comprises a plurality of pixel regions in an array along intersected first and second directions. The pixel region includes at least three subpixel regions. At least one subpixel region serves as an adjustment-subpixel region. The subpixel region has a first electrode including at least two parallel first straight portions. Second straight portions and first connecting portions are connected to first and second ends of the first straight portions, respectively. The first electrode corresponding to the adjustment-subpixel region serves as an adjustment electrode. An opening is configured at an end between the at least two adjacent second straight portions corresponding to the adjustment electrode. An angle between extending direction of the first straight portion and the second direction is less than an angle between extending direction of the second straight portion and the second direction.Type: ApplicationFiled: May 30, 2018Publication date: August 1, 2019Inventors: Yujiao LIANG, Liting FANG, Ankai LING, Yanping YU, Boping SHEN
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Publication number: 20190203231Abstract: The present invention relates to methods for treating prostate cancer patients. It is based, at least in part, on the discovery that approximately 90% of men carrying at least one of the following fusion genes: TRMT11-GRIK2, SLC45A2-AMACR, MTOR-TP53BP1, LRRC59-FLJ60017, TMEM135-CCDC67 and CCNH-C5orf30 experienced prostate cancer recurrence, metastases and/or prostate cancer-specific death after radical prostatectomy (each examples of “progressive prostate cancer”), while these outcomes occurred in only 36% of men not carrying any of these fusion genes. It is also based, at least in part, on the discovery that a genome editing technique that specifically targets a fusion gene can induce cell death in a cancer cell that carries the fusion gene.Type: ApplicationFiled: March 18, 2019Publication date: July 4, 2019Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONInventors: Jianhua Luo, Yanping Yu, Zhanghui Chen, George Konstantine Michalopoulos, Joel Nelson
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Patent number: 10308960Abstract: The present invention relates to methods for treating prostate cancer patients. It is based, at least in part, on the discovery that approximately 90% of men carrying at least one of the following fusion genes: TRMT11-GRIK2, SLC45A2-AMACR, MTOR-TP53BP1, LRRC59-FLJ60017, TMEM135-CCDC67 and CCNH-05orf30 experienced prostate cancer recurrence, metastases and/or prostate cancer-specific death after radical prostatectomy (each examples of “progressive prostate cancer”), while these outcomes occurred in only 36% of men not carrying any of these fusion genes. It is also based, at least in part, on the discovery that a genome editing technique that specifically targets a fusion gene can induce cell death in a cancer cell that carries the fusion gene.Type: GrantFiled: January 13, 2017Date of Patent: June 4, 2019Assignee: University of Pittsburgh - of the Commonwealth System of Higher EducationInventors: Jianhua Luo, Yanping Yu, Zhanghui Chen, George Konstantine Michalopoulos, Joel Nelson
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Publication number: 20190062974Abstract: The invention discloses a method for preparing a hollow textile with a core-spun yarn of short-staple wrapped microporous alkali-soluble polyester filament, which includes a foaming microcapsule preparation step, a preparation step of alkali-soluble chips containing foaming microcapsules, a melt foaming and spinning step, and a hollow textile preparation step. In the method for preparing the hollow textile with the core-spun yarn of short-staple wrapped microporous alkali-soluble polyester filament, a hollow yarn or a hollow fabric is made from a polyester filament having a microporous structure through alkali dissolution. The polyester filament having a microporous structure can effectively increase the contact area of the alkali dissolution and has the advantages of high dissolution rate, short dissolution time and complete dissolution.Type: ApplicationFiled: September 19, 2017Publication date: February 28, 2019Inventors: Yanping YU, Weiguo LIU, Erqi YU, Junhe LIU
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Publication number: 20180348580Abstract: The present disclosure relates to a liquid crystal display panel and a display device. The liquid crystal display panel includes a display area; and a non-display area surrounding the display area, wherein the display area includes a plurality of sub-areas, each of the plurality of sub-areas is provided with a plurality of pixel electrodes, all of the pixel electrodes in a sub-area have an identical brightness control parameter; and the brightness control parameter of the pixel electrodes in at least one sub-area is different from the brightness control parameter of the pixel electrodes in another sub-area. By setting different brightness control parameters based on different temperature rise in the sub-areas, the problem of poor Gamma uniformity of the display panel can be solved, and the possibility of occurrence of ghost can be reduced, thereby increasing display quality of the liquid crystal display panel.Type: ApplicationFiled: October 27, 2017Publication date: December 6, 2018Inventors: Ankai LING, Yanping YU, Boping SHEN
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Publication number: 20180230547Abstract: The present invention relates to methods for determining whether a subject having prostate cancer is at an increased risk for relapse or rapid relapse. It is based, at least in part, on the results of a comprehensive genome analysis of 273 prostate cancer samples, which indicate that the percentage of large size CNVs predicts prostate cancer relapse. In certain embodiments, a method for determining whether a prostate cancer patient has an increased risk of suffering a relapse or a rapid relapse comprises determining the number and size of CNVs in a sample and determining a large size ratio, where if the large size ratio exceeds a particular threshold, the patient is deemed to be at an increased risk for relapse or rapid relapse.Type: ApplicationFiled: February 7, 2018Publication date: August 16, 2018Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONInventors: Jianhua Luo, Yanping Yu, Chien-Cheng Tseng, Shuchang Liu, George Michalopoulos, Joel Nelson
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Publication number: 20180105962Abstract: The present invention discloses a warp-knitted fabric of filament and short staple composite yarn and a preparation method thereof. The warp-knitted fabric of filament and short staple composite yarn is prepared by the corresponding preparation method for the warp-knitted fabric of filament and short staple composite yarn. The preparation method for the warp-knitted fabric of filament and short staple composite yarn has excellent weavability, and can effectively prepare the warp-knitted fabric which is high in size stability, is soft, has high elasticity, is wrinkle-resistant and has an excellent hand feeling and comfort. Moreover, in the preparation method, soluble fiber filaments can be added to prepare a warp-knitted fabric or a 3D interval warp-knitted fabric which is partially or entirely formed by 100% short staple yarns; and low-melting-point filaments can also be added to prepare a warp-knitted fabric which can be randomly cut and has no edge curling variation.Type: ApplicationFiled: November 2, 2016Publication date: April 19, 2018Inventors: Yanping YU, Weiguo LIU, Zongwen WANG, Erqi YU, Junhe LIU, Yiming GAO
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Publication number: 20180105960Abstract: The present application discloses a novel light flame-retardant heat-insulated warm-retention protective fabric and a preparation method thereof. The preparation method comprises the steps of making soluble fibers and wrapping fibers into core spun yarns by ring spun core-spun spinning method, and weaving the made core spun yarns into a grey fabric by a loom; and then dissolving the soluble fibers in the grey fabric, and finally making the grey fabric into the novel light flame-retardant heat-insulated warm-retention protective fabric upon dyeing and finishing procedures. The protective fabric is a hollow yarn fabric and includes conventional woven goods and knit goods, still air will be generated among the yarns. With respect to the protective fabric with flowing air in the prior art, the protective fabric of the present invention has the advantages of better heat insulation and warm retention, lighter weight and stronger comfort.Type: ApplicationFiled: November 1, 2016Publication date: April 19, 2018Inventors: Yanping YU, Weiguo LIU, Erqi YU, Junhe LIU
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Publication number: 20180002837Abstract: The invention discloses a technology for recovery, regeneration and reuse of soluble textiles. The technology comprises the steps of: the dissolution-controlled soluble polyester fibres are processed into soluble apparel accessories through conventional weaving, dyeing, finishing and tailoring or injection molding; the apparels or the soluble apparel accessories are dissolved under a certain condition, on one hand, the dissolving solution is filtered and solutes are recovered to obtain a high purity of terephthalic acid and ethylene glycol, which are reused to the polymerization of the soluble polyester, and the slices of the soluble polyester are obtained to be re-spun into the soluble fibres for reuse; on the other hand, the incompact and undissolved textiles are treated into an incompact fibre aggregation with good qualities by processes including disinfection, decolourization or redyeing, which are processed into high-quality textile fibres for reuse after drying or softly carding.Type: ApplicationFiled: October 24, 2016Publication date: January 4, 2018Inventors: Yanping YU, Weiguo LIU, Erqi YU, Junhe LIU
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Publication number: 20170313683Abstract: Provided are a series of BTK inhibitors, and specifically disclosed are a compound, pharmaceutically acceptable salt thereof, tautomer thereof or prodrug thereof represented by formula (I), (II), (III) or (IV).Type: ApplicationFiled: July 14, 2017Publication date: November 2, 2017Inventors: Xuehai Wang, Chengde Wu, Yong Xu, Chunli Shen, Li'e Li, Guoping Hu, Yang Yue, Jian Li, Diliang Guo, Nengyang Shi, Lu Huang, Shuhui Chen, Ronghua Tu, Zhongwen Yang, Xuwen Zhang, Qiang Xiao, Hua Tian, Yanping Yu, Hailiang Chen, Wenjie Sun, Zhenyu He, Jie Shen, Jing Yang, Jing Tang, Wen Zhou, Jing Yu, Yi Zhang, Quan Liu
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Publication number: 20170240924Abstract: The present invention relates to methods for treating prostate cancer patients. It is based, at least in part, on the discovery that approximately 90% of men carrying at least one of the following fusion genes: TRMT11-GRIK2, SLC45A2-AMACR, MTOR-TP53BP1, LRRC59-FLJ60017, TMEM135-CCDC67 and CCNH-C5orf30 experienced prostate cancer recurrence, metastases and/or prostate cancer-specific death after radical prostatectomy (each examples of “progressive prostate cancer”), while these outcomes occurred in only 36% of men not carrying any of these fusion genes. It is also based, at least in part, on the discovery that a genome editing technique that specifically targets a fusion gene can induce cell death in a cancer cell that carries the fusion gene.Type: ApplicationFiled: January 13, 2017Publication date: August 24, 2017Inventors: JIANHUA LUO, Yanping Yu, Zhanghui Chen, George Konstantine Michalopoulos, Joel Nelson
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Patent number: 9724374Abstract: A capsule containing total flavonoids of Desmodium styracifolium, a method for preparing the same and a use of the capsule containing total flavonoids of Desmodium styracifolium are provided. Specifically, the capsule includes total flavonoids of Desmodium Styracifolium provided in a form of alcohol extract of Desmodium Styracifolium and a pharmaceutically acceptable excipient.Type: GrantFiled: July 15, 2014Date of Patent: August 8, 2017Assignees: HUMANWELL HEALTHCARE (GROUP) CO., LTD., WUHAN OPTICS VALLEY HUMANWELL BIO-PHARMACEUTICAL CO., LTD., HUBEI BIOLOGICAL MEDICINE INDUSTRIAL TECHNOLOGY INSTITUTE CO., LTD., WUHAN CHEMLIGAND BIO-PHARMACEUTICAL CO., LTD.Inventors: Xuehai Wang, Yong Xu, Li'e Li, Jie Li, Ronghua Tu, Gang Chen, Rubin Cao, Yun Feng, Zhongwen Yang, Zhaoze Fan, Yanping Yu, Qiang Xiao, Lu Huang, Chengbing Yang, Tianci Huang, Hua Tian, Jing Yang
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Publication number: 20170175323Abstract: The present invention discloses a method for preparing untwisted, hollow, high-count textiles comprising the following steps: a. preparing an alkaline degradable slice; b. preparing a blended spun melt; c. preparing an easily alkaline soluble and degradable fiber by spinning; d. preparing the textiles or an embroidered article. A method for recovering the solute in an alkaline lysis solution comprises an alkaline lysis solution obtained after the degradation of the easily alkaline soluble and degradable fiber is subjected to an acid precipitation, so as to produce terephthalic acid, wherein the waste water obtained by filtering meets the emission standard and is introduced to a biochemistry processing system.Type: ApplicationFiled: January 15, 2016Publication date: June 22, 2017Inventors: Yanping YU, Weiguo LIU, Erqi YU, Junhe LIU
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Publication number: 20150284881Abstract: The invention discloses the processing method of a non-PVA fiber hollow yarn and the tubular fabric. The fiber shall include filament yarn, staple yarn and ribbon. The processing method applies degradable fiber which is controllable in degradation conditions and has none formaldehyde residue to produce hollow yarn, in contrast with conventional soluble Vinylon hollow yarn, which is environmentally friendly and cheap while has low shrinkage and distinct hollow effect as can be made into high density textile and single yarn textile through sizing process. Furthermore, the tubular fabric as described in this invention spinned with the non-PVA fiber hollow yarn is feature with lightness, fluffy sense, warmth, moisture absorption and softness.Type: ApplicationFiled: December 11, 2014Publication date: October 8, 2015Inventors: Yanping YU, Weiguo LIU
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Publication number: 20150050647Abstract: The present invention relates to methods and compositions for diagnosing prostate cancer and/or determining whether a prostate cancer patient is at increased risk of suffering a relapse, or a rapid relapse, of his cancer. It is based, at least in part, on the results of a comprehensive genome analysis on 241 prostate cancer samples (104 prostate cancer, 85 matched bloods, 49 matched benign prostate tissues adjacent to cancer, and 3 cell lines) which indicate that (i) genome copy number variation (CNV) occurred in both cancer and non-cancer tissues, and (ii) CNV predicts prostate cancer progression.Type: ApplicationFiled: July 21, 2014Publication date: February 19, 2015Applicant: University of Pittsburgh - of the Commonwealth System of Higher EducationInventors: JIANHUA LUO, George Konstantine Michalopoulos, Joel B. Nelson, Chi Song, Chien-Cheng Tseng, Yanping Yu
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Publication number: 20130079241Abstract: The present invention relates to methods and compositions for diagnosing prostate cancer and/or determining whether a prostate cancer patient is at increased risk of suffering a relapse, or a rapid relapse, of his cancer. It is based, at least in part, on the results of a comprehensive genome analysis on 241 prostate cancer samples (104 prostate cancer, 85 matched bloods, 49 matched benign prostate tissues adjacent to cancer, and 3 cell lines) which indicate that (i) genome copy number variation (CNV) occurred in both cancer and non-cancer tissues, and (ii) CNV predicts prostate cancer progression.Type: ApplicationFiled: September 14, 2012Publication date: March 28, 2013Inventors: Jianhua Luo, George Konstantine Michalopoulos, Joel Byron Nelson, Chi Song, Chien-Cheng Tseng, Yanping Yu