Abstract: The present application relates to a pregabalin sustained release composition, comprising: (a) an active ingredient; (b) a matrix-forming agent; (c) a swelling agent; (d) a gelling agent; and optionally a filler. The pregabalin sustained release composition provided in the present application can rapidly swell in volume when exposed to aqueous medium until exceeding the dimeter of human gastric pyloric (13 mm). It thereby prolongs the gastric emptying time to increase the retention time of pregabalin in the stomach and enhances absorption of pregabalin in the small intestine and ascending colon. Moreover, the pregabalin sustained release composition provided herein achieves a sustained release for 24 h, which allows QD (once a day) administration, reduces administration number, and improves patient compliance.

Abstract: A local area network (LAN) communication management method includes obtaining, by an access and mobility management function (AMF) network element, registration area information of the terminal, the LAN identifier (ID) of the terminal, and the service area information corresponding to the LAN ID, determining, by the AMF network element, LAN communication area information of the terminal based on the registration area information of the terminal and the service area information corresponding to the LAN ID, sending, by the AMF network element, LAN information of the terminal to the terminal, where the LAN information of the terminal includes the LAN ID and the LAN communication area information of the terminal, and managing, by the terminal, LAN communication of the terminal based on the LAN information.