Abstract: The present application relates to optical fibers having at least one slot. The optical fiber may be used, for example, in various sensing application. In some embodiments, a cross-section of the optical fiber perpendicular to the longitudinal axis has a largest dimension less than or equal to about 4 ?m, and the slot has a width of about 5 nm to about 500 nm and a depth of at least about 10 nm. Also disclosed herein are methods of using the optical fibers and apparatuses including the optical fibers.

Abstract: Technologies are generally described for techniques useful in an interferometer system. In some examples, a system may include a first waveguide effective to propagate a first wave in a first mode. In some examples, the system may include a second waveguide effective to, in response to the first wave, propagate second and third waves in second and third modes, respectively. In some examples, the second waveguide may be effective to reflect the second and third waves off a reflection surface to produce first, second, third and fourth reflected waves. In some examples, the second waveguide may be effective to propagate the first and third reflected waves in the second mode and propagate the second and fourth reflected waves in the third mode.

Abstract: A novel method suitable for commercially mass production of hollow microneedle with high quality for delivery of drugs across or into biological tissue is provided. It typically includes the following processes: (1) coating an elongated template of a first material with a second material to form a cover; (2) removing tips of the template and cover to form an opening in the cover; and (3) removing the template of the first material to obtain hollow microneedles of the second material. This simple, efficient and cost-effective fabrication method can mass produce hollow microneedle arrays involving no complicated and expensive equipments or techniques, which can be used in commercial fabrication of hollow needles for delivering drugs or genes across or into skin or other tissue barriers with advantages of minimal damage, painless, long-term and continuous usages.

Abstract: A novel method suitable for commercially mass production of hollow microneedle with high quality for delivery of drugs across or into biological tissue is provided. It typically includes the following processes: (1) coating an elongated template of a first material with a second material to form a cover; (2) removing tips of the template and cover to form an opening in the cover; and (3) removing the template of the first material to obtain hollow microneedles of the second material. This simple, efficient and cost-effective fabrication method can mass produce hollow microneedle arrays involving no complicated and expensive equipments or techniques, which can be used in commercial fabrication of hollow needles for delivering drugs or genes across or into skin or other tissue barriers with advantages of minimal damage, painless, long-term and continuous usages.

Abstract: An optical device for demultiplexing an optical signal comprises a grating that receives an optical signal comprising a plurality of wavelength channels, and generates a plurality of spatially separated light beams. Each light beam is associated with a particular wavelength channel. The optical device further comprises an optical element that at least partially compensates a temperature based frequency shift associated with the spatially separated light beams. The optical device further comprises a plurality of lenses and a plurality of fibers. The plurality of lenses are arranged such that a spacing between at least a pair of lenses is determined to at least partially compensate a non-linearity introduced by the grating. Each fiber is associated with a corresponding lens and receives a corresponding light beam. At least one fiber is placed a distance that is less than a focal length associated with its corresponding lens.

Abstract: An optical device for demultiplexing an optical signal comprises a grating that receives an optical signal comprising a plurality of wavelength channels, and generates a plurality of spatially separated light beams. Each light beam is associated with a particular wavelength channel. The optical device further comprises an optical element that at least partially compensates a temperature based frequency shift associated with the spatially separated light beams. The optical device further comprises a plurality of lenses and a plurality of fibers. The plurality of lenses are arranged such that a spacing between at least a pair of lenses is determined to at least partially compensate a non-linearity introduced by the grating. Each fiber is associated with a corresponding lens and receives a corresponding light beam. At least one fiber is placed a distance that is less than a focal length associated with its corresponding lens.