Abstract: The present disclosure relates to the biopharmaceutical field, in particular, Exatecan derivatives, linker-payloads, and conjugates and thereof antibody-drug conjugates, and the corresponding preparing process and use thereof.

Abstract: A power system, responsive to a detected change in an onboard charger or a generator, switches a converter from a first conversion setting, in which a first low voltage value of a medium-voltage bus port is converted to a first high voltage value of a high-voltage bus port, to a second conversion setting, in which a second low voltage value of the medium-voltage bus port is converted to the first high voltage value of the high-voltage bus port.

Abstract: A power supply can include a bulk capacitor that receives a DC bus voltage; one or more DC-DC converters that convert the DC bus voltage to a DC output voltage; an inrush current limiting circuit that includes a resistor coupled in series with the bulk capacitor so as to limit an inrush current to the bulk capacitor; and a solid-state switching device that selectively bypasses the resistor once the bulk capacitor is charged; and control circuitry that operates the solid-state switching device to selectively bypass the resistor once the bulk capacitor is charged. The inrush current limiting circuit can further include a relay responsive to the control circuitry that selectively bypasses the resistor under high load conditions once the bulk capacitor is charged; and the control circuitry can further operate the solid-state switching device to selectively bypass the resistor once the bulk capacitor is charged under low load conditions.

Abstract: A power converter can include a DC-DC converter having an output with an active power buffer coupled thereto. The active power buffer can include an energy storage capacitor and one or more switching devices selectively coupling the capacitor to the output to alternately store energy in and discharge energy from the capacitor. Control circuitry can include a DC-DC converter control loop that operates the DC-DC converter to regulate an average voltage across the capacitor and an active power buffer control loop that operates the one or more switching devices of the active power buffer to regulate an output voltage of the power converter. The DC-DC converter control loop can include a relatively slower control loop that controls the DC-DC converter during steady state load conditions and at least one relatively faster control loop that controls the DC-DC converter during transient load conditions.

Abstract: Provided herein are systems and methods for configuring data recovery. A method includes decoding, by at least one hardware processor, a request to recover historical table data. The request is received from an account of a data provider. The historical table data includes a plurality of partition files. Each of the plurality of partition files includes a deleted file designation. Based on the request, a recovery process of the plurality of partition files is performed to obtain recovered partition files. A schema associated with the historical table data is retrieved. Metadata corresponding to the retrieved schema is generated. The metadata is associated with the recovered partition files to recover the historical table data.

Abstract: A power system includes a DC/AC converter, a traction battery, an AC/DC converter electrically connected between the DC/AC converter and traction battery, and a transformer electrically connected between the DC/AC converter and AC/DC converter. The AC/DC converter includes a plurality of semiconductor devices and a plurality of capacitors such that during power transfer from the DC/AC converter to the traction battery, a voltage across each of the capacitors is half of a battery voltage.

Abstract: A power converter has a pair of series connected switches defining a phase leg, a pair of gate driver circuits that respectively provide power to gates of the series connected switches, a positive rail electrically connected with the phase leg, and a clamping circuit including a clamping switch. The clamping circuit, responsive to one of the gate driver circuits being de-energized, activates the clamping switch with energy from the positive rail to clamp a gate of one of the series connected switches associated with the one of the gate driver circuits to another terminal of the one of the series connected switches.

Abstract: A power system for a vehicle includes a traction battery having an output voltage, a transformer including a coil, and a power converter including a plurality of capacitors and a plurality of switches arranged such that when a first subset of the switches are ON, two of the capacitors are in parallel, an AC voltage across the coil is in a positive half cycle, and a voltage across each of the two of the capacitors is half the output voltage.

Abstract: This disclosure is directed to power systems for transferring power between electrical components. An exemplary power system includes a first electrical component (e.g., an inverter system) having a current sensor assembly for detecting current flowing between the first electrical component and a second electrical component (e.g., an electric motor) in order to more reliably manage and control operation of the second electrical component. The current sensor assembly may include an integrated cooler that includes an internal cooling circuit configured to circulate coolant for cooling one or more bus bars of the current sensor assembly.

Abstract: A power converter can include a DC-DC converter having an output with an active power buffer coupled thereto. The active power buffer can include an energy storage capacitor and one or more switching devices selectively coupling the capacitor to the output to alternately store energy in and discharge energy from the capacitor. Control circuitry can include a DC-DC converter control loop that operates the DC-DC converter to regulate an average voltage across the capacitor and an active power buffer control loop that operates the one or more switching devices of the active power buffer to regulate an output voltage of the power converter. The DC-DC converter control loop can include a relatively slower control loop that controls the DC-DC converter during steady state load conditions and at least one relatively faster control loop that controls the DC-DC converter during transient load conditions.

Abstract: A power converter can include a rectifier that receives an AC input voltage and produces a rectified output voltage, a power factor correction (PFC) converter having an input coupled that receives the rectified output voltage of the rectifier and an output that provides an intermediate DC bus voltage, a DC-DC converter having an input that receives the intermediate DC bus voltage and produces a regulated DC output voltage, and control circuitry for the PFC converter stage that includes a relatively slower control loop that controls the PFC converter during steady state load conditions and at least one relatively faster control loop that controls the PFC converter during transient load conditions.

Abstract: A power converter includes a plurality of switches, a transformer electrically connected between some and other of the switches, and a plurality of series connected capacitors electrically connected between the switches and an output of the power converter. A controller operates the switches such that a voltage at an input of the power converter and across each of the capacitors is same and a voltage at the output is double the voltage at the input.

Abstract: An automotive vehicle includes an electric machine, a traction battery, and a power converter. The power converter transfers power between the electric machine and traction battery. The power convert includes a switch that defines a portion of a phase leg, a gate driver circuit that provides provide power to a gate of the switch, and a clamping circuit. The clamping circuit includes a clamping switch that, responsive to the gate driver circuit being de-energized and a voltage of the gate exceeding a predetermined threshold value, conducts current from the gate to dissipate the voltage and clamp the gate to an emitter of the switch.

Abstract: A power system includes a DC/AC converter, a traction battery, an AC/DC converter electrically connected between the DC/AC converter and traction battery, and a transformer electrically connected between the DC/AC converter and AC/DC converter. The AC/DC converter includes a plurality of semiconductor devices and a plurality of capacitors such that during power transfer from the DC/AC converter to the traction battery, a voltage across each of the capacitors is half of a battery voltage.

Abstract: A power system, responsive to a detected change in an onboard charger or a generator, switches a converter from a first conversion setting, in which a first low voltage value of a medium-voltage bus port is converted to a first high voltage value of a high-voltage bus port, to a second conversion setting, in which a second low voltage value of the medium-voltage bus port is converted to the first high voltage value of the high-voltage bus port.

Abstract: A power converter includes a plurality of switches, a transformer electrically connected between some and other of the switches, and a plurality of series connected capacitors electrically connected between the switches and an output of the power converter. A controller operates the switches such that a voltage at an input of the power converter and across each of the capacitors is same and a voltage at the output is double the voltage at the input.

Abstract: A power system for a vehicle includes a traction battery having an output voltage, a transformer including a coil, and a power converter including a plurality of capacitors and a plurality of switches arranged such that when a first subset of the switches are ON, two of the capacitors are in parallel, an AC voltage across the coil is in a positive half cycle, and a voltage across each of the two of the capacitors is half the output voltage.

Abstract: A vehicle power system has a DC to AC converter, a pair of AC to DC converters, a transformer including a core, a primary winding wound about the core and electrically connected to an output of the DC to AC converter, and a pair of secondary windings wound about the core, a traction battery electrically connected to a collective output of the AC to DC converters, and a controller.

Abstract: An automotive vehicle includes an electric machine, a traction battery, and a power converter. The power converter transfers power between the electric machine and traction battery. The power convert includes a switch that defines a portion of a phase leg, a gate driver circuit that provides provide power to a gate of the switch, and a clamping circuit. The clamping circuit includes a clamping switch that, responsive to the gate driver circuit being de-energized and a voltage of the gate exceeding a predetermined threshold value, conducts current from the gate to dissipate the voltage and clamp the gate to an emitter of the switch.

Abstract: This disclosure is directed to power systems for transferring power between electrical components. An exemplary power system includes a first electrical component (e.g., an inverter system) having a current sensor assembly for detecting current flowing between the first electrical component and a second electrical component (e.g., an electric motor) in order to more reliably manage and control operation of the second electrical component. The current sensor assembly may include an integrated cooler that includes an internal cooling circuit configured to circulate coolant for cooling one or more bus bars of the current sensor assembly.