Abstract: Compounds having the following formula I or a stereoisomer or pharmaceutically-acceptable salt thereof, where all substituents are as defined herein, are inhibitors of USP1 useful for treating diseases including, among others, treating proliferative, metabolic, allergic, autoimmune and inflammatory diseases.

Abstract: Disclosed are a driving method of a display panel and a display device. The driving method of the display panel includes: obtaining display data of a current display frame (S100); and inputting a data voltage to a data line according to the display data, so that the corresponding data voltages are charged into sub-pixels electrically connected to the data line (S200), where the data voltages inputted on the data line are divided into a plurality of voltage groups, each voltage group includes at least two adjacent data voltages, the polarities corresponding to the data voltages in a same voltage group are the same, the polarities corresponding to the data voltages of the two adjacent voltage groups inputted into a same data line are different, and the polarities of the corresponding voltage groups on the two adjacent data lines are different.

Abstract: A driving method for a display panel (100), and a display apparatus. The method includes: acquiring display data of a current frame and display data of a previous frame (S10); determining whether the display data of the current frame is the same as the display data of the previous frame (S20); if not, converting a default gray scale voltage corresponding to at least one sub-pixel among default gray scale voltages corresponding to a default gray scale bit number carried by the display data of the current frame into a target gray scale voltage of a target gray scale bit number, and driving the display panel (100) to display (S30).

Abstract: Disclosed are a driving method of a display panel and a display device. The driving method of the display panel includes: obtaining display data of a current display frame (S100); and inputting a data voltage to a data line according to the display data, so that the corresponding data voltages are charged into sub-pixels electrically connected to the data line (S200), where the data voltages inputted on the data line are divided into a plurality of voltage groups, each voltage group includes at least two adjacent data voltages, the polarities corresponding to the data voltages in a same voltage group are the same, the polarities corresponding to the data voltages of the two adjacent voltage groups inputted into a same data line are different, and the polarities of the corresponding voltage groups on the two adjacent data lines are different.

Abstract: A driving method for a display panel (100), and a display apparatus. The method includes: acquiring display data of a current frame and display data of a previous frame (S10); determining whether the display data of the current frame is the same as the display data of the previous frame (S20); if not, converting a default gray scale voltage corresponding to at least one sub-pixel among default gray scale voltages corresponding to a default gray scale bit number carried by the display data of the current frame into a target gray scale voltage of a target gray scale bit number, and driving the display panel (100) to display (S30).

Abstract: A method for driving a display panel and a display device, the method includes: acquiring an original grayscale value of each sub-pixel in an mth row and a target grayscale value corresponding to a data voltage input to each sub-pixel in an (m?1)th row m being an integer greater than 1; if, in a same column, the original grayscale value of the sub-pixel in the mth row is larger than the target grayscale value corresponding to the data voltage input to the sub-pixel in the (m?1)th row, determining a target grayscale value of each sub-pixel in the mth row according to the original grayscale value of the sub-pixel in the mth row and the target grayscale value of the sub-pixel in the (m?1)th row inputting a data voltage to a data line in the display panel according to the target grayscale value of each sub-pixel in the mth row.

Abstract: A driving method of a display panel and a display apparatus provided by embodiments of the present disclosure include: when a display mode switching startup instruction is received, a non-counting state is entered. The display panel is driven to display a first set picture, and a current display mode is switched to a target display mode. When a data mode switching completing instruction is received, a counting state is entered.

Abstract: The present disclosure provides a circuit board, a chip on film, a display apparatus and a bonding method. The circuit board has a plurality of bonding regions for bonding with a chip on film, each bonding region includes: a plurality of first pins extending along a first direction and sequentially arranged along a second direction; and at least one first alignment mark group on an arrangement path along which the plurality of first pins are arranged and configured to be aligned with a second alignment mark group of the chip on film in a buckled way, so that the plurality of first pins are bonded and attached to second pins of the chip on film in one-to-one correspondence.

Abstract: Disclosed are a method for adjusting a signal of a display panel, a time controller integrated circuit, a display panel, and a storage medium. The method includes: converting first data into a first data voltage signal using a first data voltage, in response to a set condition being reached, sending the first data voltage signal to a chip on film integrated circuit, the chip on film integrated circuit identifies the first data voltage signal to obtain a second data; acquiring the second data from the chip on film integrated circuit, determining that the chip on film integrated circuit fails to identify the first data in response to the second data being different from the first data; and adjusting the first data voltage until a second data voltage signal converted from the first data using a second data voltage after adjustment being successfully identified by the chip on film integrated circuit.

Abstract: Disclosed are a method for adjusting a signal of a display panel, a time controller integrated circuit, a display panel, and a storage medium. The method includes: converting first data into a first data voltage signal using a first data voltage, in response to a set condition being reached, sending the first data voltage signal to a chip on film integrated circuit, the chip on film integrated circuit identifies the first data voltage signal to obtain a second data; acquiring the second data from the chip on film integrated circuit, determining that the chip on film integrated circuit fails to identify the first data in response to the second data being different from the first data; and adjusting the first data voltage until a second data voltage signal converted from the first data using a second data voltage after adjustment being successfully identified by the chip on film integrated circuit.

Abstract: A license plate character recognition method and apparatus, an electronic device, and a storage medium. The method comprises: after obtaining a vehicle image captured by an image capturing device, positioning a vehicle plate area in the vehicle image to obtain a license plate image, and performing feature extraction on the license plate image by means of a convolutional neural network comprising a residual network structure. Gradient vanishing is effectively avoided and feature loss in a convolutional process of the convolutional neural network is reduced, so that a bidirectional recurrent neural network model can accurately recognize license plate characters in the license plate image on the basis of feature information of the license plate image.

Abstract: A control method of a display apparatus is provided. The method includes: obtaining to-be-displayed data; starting to generate first image data of a first display panel based on the to-be-displayed data; sending image data to a second processing component based on the to-be-displayed data; and after generating the first image data, delaying sending the first image data to the first display panel based on a first difference between second duration taken by the second processing component to generate second image data and first duration taken by a first processing component to generate the first image data.

Abstract: The present invention provides compounds of Formula (I), or stereoisomers, tautomers, or pharmaceutically acceptable salts or solvates thereof, wherein all the variables are as defined herein. These compounds modulate the activity of farnesoid X receptor (FXR), for example, as agonists. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating a disease, disorder, or condition associated with FXR dysregulation, such as pathological fibrosis, transplant rejection, cancer, osteoporosis, and inflammatory disorders, by using the compounds and pharmaceutical compositions.

Abstract: The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts or solvates thereof, wherein all the variables are as defined herein. These compounds modulate the activity of famesoid X receptor (FXR), for example, as agonists. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating a disease, disorder, or condition associated with FXR dysregulation, such as pathological fibrosis, transplant rejection, cancer, osteoporosis, and inflammatory disorders, by using the compounds and pharmaceutical compositions.

Abstract: The present invention provides compounds of Formula (I), or stereoisomers, tautomers, or pharmaceutically acceptable salts or solvates thereof, wherein all the variables are as defined herein. These compounds modulate the activity of farnesoid X receptor (FXR), for example, as agonists. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating a disease, disorder, or condition associated with FXR dysregulation, such as pathological fibrosis, transplant rejection, cancer, osteoporosis, and inflammatory disorders, by using the compounds and pharmaceutical compositions.

Abstract: The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts or solvates thereof, wherein all the variables are as defined herein. These compounds modulate the activity of farnesoid X receptor (FXR), for example, as agonists. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating a disease, disorder, or condition associated with FXR dysregulation, such as pathological fibrosis, transplant rejection, cancer, osteoporosis, and inflammatory disorders, by using the compounds and pharmaceutical compositions.

Abstract: The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts or solvates thereof, wherein all the variables are as defined herein. These compounds modulate the activity of famesoid X receptor (FXR), for example, as agonists. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating a disease, disorder, or condition associated with FXR dysregulation, such as pathological fibrosis, transplant rejection, cancer, osteoporosis, and inflammatory disorders, by using the compounds and pharmaceutical compositions.

Abstract: The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts or solvates thereof, wherein all the variables are as defined herein. These compounds modulate the activity of farnesoid X receptor (FXR), for example, as agonists. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating a disease, disorder, or condition associated with FXR dysregulation, such as pathological fibrosis, transplant rejection, cancer, osteoporosis, and inflammatory disorders, by using the compounds and pharmaceutical compositions.

Abstract: The present invention provides compounds of Formula (I), or a pharmaceutically acceptable salt thereof, wherein A is a five to eight membered monocyclic or a nine to twelve membered bicyclic heterocyclic ring, as further defined herein; Y is S, CH2, or CH; Z is CH or N; R7 and R9 are hydrogen or (C1-C6)alkyl; R2 is (C1-C6)alkoxy, OH, CN, (C1-C6)alkyl, halogen, or CF3; r and s are 0, 1, or 2; and R1 and R3 are as further defined herein. These compounds are agonists, partial agonists and/or modulators of the NPY4 receptor and may be used for the treatment and prophylaxis of obesity, food intake, and other diseases and conditions modulated by the NPY4 receptor.

Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are agonists, partial agonists and modulators of the NPY Y4 receptor and may be used for the treatment and prophylaxis of various diseases and conditions.