Abstract: The present invention relates to microorganisms comprising each of each of an ApxIA, ApxIIA and ApxIIIA toxin, related vaccines and methods of production thereof, as well as uses thereof for the immunisation and protection of mammals.

Abstract: A magnetic liquid damping shock absorber includes a housing, a thermal insulating material layer, a mass block and a magnetic liquid. The housing defines a sealed cavity, the sealed cavity has a first wall face and a second wall face opposite in a first direction and a circumferential wall face located between the first wall face and the second wall face in the first direction. The thermal insulating material layer is provided on an outer surface of the housing, on a wall face of the sealed cavity or in a housing wall of the housing. The mass block is located in the sealed cavity, and the mass block and the housing define a magnetic liquid cavity therebetween. The magnetic liquid is filled in the magnetic liquid cavity.

Abstract: A chain unit lubricated and sealed with magnetic fluid includes a pin shaft, a magnetic sleeve, a first pole piece and a second pole piece. The sleeve is fitted over an outer periphery of the pin shaft. Both ends of the pin shaft protrude from the sleeve. A first gap exists between an inner peripheral surface of the sleeve and an outer peripheral surface of the pin shaft. The first pole piece is arranged at one of the sleeve and has a first mating hole. A second gap exists between an inner wall surface of the first mating hole and the outer peripheral surface of the pin shaft. The second pole piece is arranged at the other end of the sleeve and has a second mating hole. A third gap exists between an inner wall surface of the second mating hole and the outer peripheral surface of the pin shaft.

Abstract: A magnetic liquid damping shock absorber includes a housing, a thermal insulating material layer, a mass block and a magnetic liquid. The housing defines a sealed cavity, the sealed cavity has a first wall face and a second wall face opposite in a first direction and a circumferential wall face located between the first wall face and the second wall face in the first direction. The thermal insulating material layer is provided on an outer surface of the housing, on a wall face of the sealed cavity or in a housing wall of the housing. The mass block is located in the sealed cavity, and the mass block and the housing define a magnetic liquid cavity therebetween. The magnetic liquid is filled in the magnetic liquid cavity.

Abstract: A chain unit lubricated and sealed with magnetic fluid includes a pin shaft, a magnetic sleeve, a first pole piece and a second pole piece. The sleeve is fitted over an outer periphery of the pin shaft. Both ends of the pin shaft protrude from the sleeve. A first gap exists between an inner peripheral surface of the sleeve and an outer peripheral surface of the pin shaft. The first pole piece is arranged at one of the sleeve and has a first mating hole. A second gap exists between an inner wall surface of the first mating hole and the outer peripheral surface of the pin shaft. The second pole piece is arranged at the other end of the sleeve and has a second mating hole. A third gap exists between an inner wall surface of the second mating hole and the outer peripheral surface of the pin shaft.

Abstract: A combined sealing device with magnetic fluid includes a housing having a chamber; a rotating shaft rotatably arranged in the chamber; a seal assembly fitted over the rotating shaft and located in the chamber, in which the seal assembly includes a brush seal part, a magnetic fluid seal part, and a labyrinth seal part all fitted over the rotating shaft and spaced apart from one another in an axial direction of the rotating shaft, the brush seal part being arranged adjacent to the sealing cavity, and the magnetic fluid seal part being arranged between the brush seal part and the labyrinth seal part; and an absorption part arranged in the brush seal part and configured to adsorb a sealing medium spilled from the sealing cavity.

Abstract: Various polypeptides, or a variant or fragment thereof or a fusion of these are described which are useful in a vaccine. The polypeptide may be a polypeptide comprising the amino acid sequence selected from any one of SEQ ID Nos 2, 4, 6, 8, 10, 12, 14; or a fragment or variant thereof or a fusion of such a fragment or variant, and is useful in a vaccine against Neisseria meningitidis.

Abstract: Various polypeptides, or a variant or fragment thereof or a fusion of these are described which are useful in a vaccine. The polypeptide may be a polypeptide comprising the amino acid sequence selected from any one of SEQ ID Nos (2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, 24, 26, 28, 30, 32, 34, 36, 38, 40, 42, 44, 46, 48, 50, 52, 54, 56, 58, 60, 62, 64, 66, 68); or a fragment or variant thereof or a fusion of such fragment or variant, and is useful in a vaccine against Neisseira meningitidis.

Abstract: A method for identifying a polypeptide of a microorganism which polypeptide is associated with an immune response in an animal which has been subjected to the microorganism, the method comprising the steps of (1) providing a plurality of different mutants of the microorganism; (2) contacting the plurality of mutant microorganisms with antibodies from an animal which has raised an immune response to the microorganism or a part thereof, under conditions whereby if the antibodies bind to the mutant microorganism the mutant microorganism is killed; (3) selecting surviving mutant microorganisms from step (2); (4) identifying the gene containing the mutation in any surviving mutant microorganism; and (5) identifying the polypeptide encoded by the gene. The polypeptide identified or a variant or fragment thereof or a fusion of these is useful in a vaccine.