Patents by Inventor Yanxiao Zhang

Yanxiao Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immobilized G-protein coupled receptors on liquid chromatography stationary phases and use thereof for on-line screening
    Publication number: 20030006192
    Abstract: This invention provides an immobilized G-protein coupled receptor (GPCR) on a support in a liquid chromatography system. The method of the invention provides means of evaluating the attachment of an agent to a GPCR comprising the steps of: (a) immobilizing a GPCR on an artificial membrane support in a column, (b) exposing the support with the GPCR to test the agent at varying concentrations in a liquid chromatography system, (c) eluting the test agent from the column, and (d) evaluating the elution profile of the test material from the column. Using this method, it is possible to evaluate the interaction of the test agent with the GPCR. Following elution, it is possible to directly determine molecular structure by passing the elute through other testing devices such as a mass spectrometer.
    Type: Application
    Filed: June 5, 2002
    Publication date: January 9, 2003
    Inventors: Irving Wainer, Yanxiao Zhang, Farideh Beigi, Ruin Moaddel
  • Immobilization of membrane receptor on HPLC
    Publication number: 20020125194
    Abstract: This invention provides a immobilized receptors on supports in liquid chromatographic systems.
    Type: Application
    Filed: May 13, 2002
    Publication date: September 12, 2002
    Inventors: Irving Wainer, Yanxiao Zhang
  • Immobilization of membrane receptor on HPLC
    Patent number: 6387268
    Abstract: This invention provides a immobilized receptors on supports in liquid chromatographic systems. The method of the invention provides means of evaluating the attachment of agents to receptors comprising the steps of: (a) immobilizing receptors on artificial membrane supports in a column, (b) exposing the supports with the receptors to test agents at varying concentrations in a liquid chromatographic system, (c) eluting the test agent from the column, and (d) evaluating the elution profile of the test materials from the column. Using this method, it is possible to evaluate the interaction of the test agent with the receptor. Following elution, it is possible to directly determine molecular structure by passing the elute through other testing devices such as a mass spectrometer.
    Type: Grant
    Filed: July 19, 2000
    Date of Patent: May 14, 2002
    Assignee: Rett Corporation
    Inventors: Irving Wainer, Yanxiao Zhang
  • Immobilization of membrane receptor on HPLC
    Patent number: 6139735
    Abstract: This invention provides a immobilized receptors on supports in liquid chromatographic systems. The method of the invention provides means of evaluating the attachment of agents to receptors comprising the steps of:(a) immobilizing receptors on artificial membrane supports in a column,(b) exposing the supports with the receptors to test agents at varying concentrations in a liquid chromatographic system,(c) eluting the test agent from the column, and(d) evaluating the elution profile of the test materials from the column.Using this method, it is possible to evaluate the interaction of the test agent with the receptor. Following elution, it is possible to directly determine molecular structure by passing the elute through other testing devices such as a mass spectrometer.
    Type: Grant
    Filed: February 23, 1999
    Date of Patent: October 31, 2000
    Assignee: Georgetown University
    Inventors: Irving Wainer, Yanxiao Zhang