Patents by Inventor Yanxin Shen

Yanxin Shen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11970702
    Abstract: The present invention generally relates to methods and materials involved in producing tobacco plants having reduced levels of conversion of nicotine to nornicotine. In certain embodiments, the invention is directed to mutations in a nicotine demethylase gene, tobacco plants comprising mutations in a nicotine demethylase gene, and tobacco compositions and products thereof. In other embodiments, the invention is directed toward nicotine demethylase RNA interference, tobacco plants comprising a nicotine demethylase RNA interference transgene, and tobacco compositions and products thereof.
    Type: Grant
    Filed: April 13, 2022
    Date of Patent: April 30, 2024
    Assignee: U.S. Smokeless Tobacco Company LLC
    Inventors: Dongmei Xu, Mark T. Nielsen, Yanxin Shen
  • Publication number: 20240117371
    Abstract: Provided herein are genetic markers and a coding sequence associated with a low- or ultra-low anatabine trait in tobacco.
    Type: Application
    Filed: December 4, 2023
    Publication date: April 11, 2024
    Applicant: ALTRIA CLIENT SERVICES INC.
    Inventors: Chengalrayan KUDITHIPUDI, Alec J. HAYES, Robert Frank HART, III, Yanxin SHEN, Jesse FREDERICK, Dongmei XU
  • Publication number: 20240102038
    Abstract: The present disclosure provides the identification of genes involved in sucker growth in tobacco. Also provided are promoters that are preferentially active in tobacco axillary buds. Also provided are modified tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing modified tobacco plants comprising reduced or no sucker growth.
    Type: Application
    Filed: December 12, 2023
    Publication date: March 28, 2024
    Applicant: ALTRIA CLIENT SERVICES LLC
    Inventors: Dongmei XU, Jesse FREDERICK, Chengalrayan KUDITHIPUDI, Yanxin SHEN, James STRICKLAND, Jaemo YANG
  • Publication number: 20240067977
    Abstract: The present disclosure provides composition and methods for improving leaf quality of low-alkaloid tobacco plants. Also provided are the identification and genetic engineering of target genes (Leaf Quality Genes) for producing tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants.
    Type: Application
    Filed: October 9, 2020
    Publication date: February 29, 2024
    Applicant: ALTRIA CLIENT SERVICES LLC
    Inventors: Chengalrayan KUDITHIPUDI, Rajanikanth GOVINDARAJULU, Nazmul BHUIYAN, Raija PAYYAVULA, Yanxin SHEN, Dongmei XU
  • Publication number: 20240035042
    Abstract: The present disclosure provides the identification of genes involved in sucker growth in tobacco. Also provided are promoters that are preferentially active in tobacco axillary buds. Also provided are modified tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing modified tobacco plants comprising reduced or no sucker growth.
    Type: Application
    Filed: September 28, 2023
    Publication date: February 1, 2024
    Applicant: ALTRIA CLIENT SERVICES LLC
    Inventors: Dongmei XU, Chengalrayan KUDITHIPUDI, Yanxin SHEN, Jaemo YANG, Jesse FREDERICK, James STRICKLAND
  • Patent number: 11879130
    Abstract: The present disclosure provides the identification of genes involved in sucker growth in tobacco. Also provided are promoters that are preferentially active in tobacco axillary buds. Also provided are modified tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing modified tobacco plants comprising reduced or no sucker growth.
    Type: Grant
    Filed: August 19, 2021
    Date of Patent: January 23, 2024
    Assignee: ALTRIA CLIENT SERVICES LLC
    Inventors: Dongmei Xu, Jesse Frederick, Chengalrayan Kudithipudi, Yanxin Shen, James Strickland, Jaemo Yang
  • Publication number: 20240018534
    Abstract: The present disclosure provides the identification of promoters that are preferentially active in tobacco axillary buds. Also provided are tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing tobacco plants comprising reduced or no sucker growth.
    Type: Application
    Filed: August 16, 2023
    Publication date: January 18, 2024
    Applicant: ALTRIA CLIENT SERVICES LLC
    Inventors: Chengalrayan KUDITHIPUDI, Jaemo YANG, Yanxin SHEN, Dongmei XU, Ujwala WAREK, James Strickland, Jesse FREDERICK
  • Publication number: 20240018536
    Abstract: The present disclosure relates to compositions and methods related to tissue-specific promoters and their uses in plants, including tobacco and Cannabis. The provided trichome-specific promoters enable the expression of heterologous polynucleotides in trichome tissues.
    Type: Application
    Filed: August 15, 2023
    Publication date: January 18, 2024
    Inventors: Chengalrayan KUDITHIPUDI, Yanxin SHEN, Dongmei XU, Michael Paul TIMKO, Roel RABARA
  • Patent number: 11873500
    Abstract: Provided herein are genetic markers and a coding sequence associated with a low- or ultra-low anatabine trait in tobacco.
    Type: Grant
    Filed: February 28, 2022
    Date of Patent: January 16, 2024
    Assignee: ALTRIA CLIENT SERVICES LLC
    Inventors: Chengalrayan Kudithipudi, Alec J. Hayes, Robert Frank Hart, Yanxin Shen, Jesse Frederick, Dongmei Xu
  • Patent number: 11845946
    Abstract: This disclosure provides tobacco plants that exhibit altered photosynthesis as well as methods of making and using such plants.
    Type: Grant
    Filed: November 3, 2021
    Date of Patent: December 19, 2023
    Assignee: Altria Client Services LLC
    Inventors: Yanxin Shen, Dongmei Xu
  • Publication number: 20230399651
    Abstract: The present disclosure provides compositions and methods related to tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants.
    Type: Application
    Filed: October 9, 2020
    Publication date: December 14, 2023
    Applicant: Altria Client Services LLC
    Inventors: Dong QI, Chengalrayan KUDITHIPUDI, Yanxin SHEN
  • Patent number: 11807860
    Abstract: The present disclosure provides the identification of genes involved in sucker growth in tobacco. Also provided are promoters that are preferentially active in tobacco axillary buds. Also provided are modified tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing modified tobacco plants comprising reduced or no sucker growth.
    Type: Grant
    Filed: June 23, 2020
    Date of Patent: November 7, 2023
    Assignee: Altria Client Services LLC
    Inventors: Dongmei Xu, Chengalrayan Kudithipudi, Yanxin Shen, Jaemo Yang, Jesse Frederick, James Strickland
  • Patent number: 11767535
    Abstract: The present disclosure provides the identification of promoters that are preferentially active in tobacco axillary buds. Also provided are tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing tobacco plants comprising reduced or no sucker growth.
    Type: Grant
    Filed: March 1, 2022
    Date of Patent: September 26, 2023
    Assignee: Altria Client Services LLC
    Inventors: Chengalrayan Kudithipudi, Jaemo Yang, Yanxin Shen, Dongmei Xu, Ujwala Warek, James Strickland, Jesse Frederick
  • Publication number: 20230247961
    Abstract: This disclosure provides a number of sequences involved in the transport of alkaloids from the root to the leaf in tobacco, methods of using such sequences, tobacco plants carrying modifications to such sequences, and tobacco products made from such plants.
    Type: Application
    Filed: August 22, 2022
    Publication date: August 10, 2023
    Applicant: ALTRIA CLIENT SERVICES LLC
    Inventors: Jesse FREDERICK, Yanxin SHEN, Dongmei XU, Ujwala WAREK, James Arthur STRICKLAND
  • Publication number: 20230203518
    Abstract: The present invention generally relates to methods and materials involved in producing tobacco plants having reduced levels of conversion of nicotine to nornicotine. In certain embodiments, the invention is directed to mutations in a nicotine demethylase gene, tobacco plants comprising mutations in a nicotine demethylase gene, and tobacco compositions and products thereof. In other embodiments, the invention is directed toward nicotine demethylase RNA interference, tobacco plants comprising a nicotine demethylase RNA interference transgene, and tobacco compositions and products thereof.
    Type: Application
    Filed: April 13, 2022
    Publication date: June 29, 2023
    Applicant: U.S. Smokeless Tobacco Company LLC
    Inventors: Dongmei XU, Mark T. Nielsen, Yanxin Shen
  • Publication number: 20230145103
    Abstract: The present disclosure provides methods and compositions for controlling sucker growth in tobacco by altering the expression of different target genes.
    Type: Application
    Filed: August 23, 2022
    Publication date: May 11, 2023
    Applicant: ALTRIA CLIENT SERVICES LLC
    Inventors: Raja S. PAYYAVULA, Yanxin SHEN, Chengalrayan KUDITHIPUDI, Rajanikanth GOVINDARAJULU
  • Publication number: 20230105789
    Abstract: The present disclosure provides compositions and methods related to tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants.
    Type: Application
    Filed: January 26, 2021
    Publication date: April 6, 2023
    Applicant: ALTRIA CLIENT SERVICES LLC
    Inventors: Chengalrayan KUDITHIPUDI, Dong QI, Yanxin SHEN, Ujwala WAREK, James STRICKLAND, Dongmei XU
  • Publication number: 20230035750
    Abstract: The present disclosure provides the identification of genes involved in sucker growth in tobacco. Also provided are promoters that are preferentially active in tobacco axillary buds. Also provided are modified tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing modified tobacco plants comprising reduced or no sucker growth.
    Type: Application
    Filed: August 19, 2021
    Publication date: February 2, 2023
    Applicant: ALTRIA CLIENT SERVICES LLC
    Inventors: Dongmei XU, Jesse FREDERICK, Chengalrayan KUDITHIPUDI, Yanxin SHEN, James STRICKLAND, Jaemo YANG
  • Publication number: 20220403402
    Abstract: The present disclosure provides approaches for reducing tobacco-specific nitrosamines (TSNAs) in tobacco. Some of these approaches include genetically engineering tobacco plants to increase one or more antioxidants, increase oxygen radicle absorbance capacity (ORAC), increase phenylalanine, or reduce nitrite. Also provided are methods and compositions for producing modified tobacco plants and tobacco products therefrom comprising reduced TSNAs.
    Type: Application
    Filed: June 1, 2022
    Publication date: December 22, 2022
    Applicant: Altria Client Services LLC
    Inventors: Chengalrayan KUDITHIPUDI, Dongmei Xu, James Strickland, Yanxin Shen
  • Publication number: 20220380788
    Abstract: The present disclosure provides compositions and methods related to tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants.
    Type: Application
    Filed: June 8, 2022
    Publication date: December 1, 2022
    Applicant: ALTRIA CLIENT SERVICES LLC
    Inventors: Chengalrayan KUDITHIPUDI, Dong QI, Yanxin SHEN, Ujwala WAREK, James A. STRICKLAND, Dongmei XU