Abstract: An antifibrotic composition includes 3-(4-(dihexylamino)-3-fluorophenyl)-2,6-dimethylpyrimidin-4(3H)-one or a pharmaceutically acceptable salt thereof and an antioxidant. The composition has the advantages of easy storage, stable and controllable quality, high bioavailability, etc. Moreover, the composition has a high efficacy and a high safety, and the compliance of a patient taking the composition is good.

Abstract: Implementations relate to reducing latency in generating and/or rendering natural language (NL) output generated using a large language model (LLM). Processor(s) of a system can: receive NL based input associated with a client device, and generate the NL based output utilizing the LLM. The NL based output can be a stream of NL based output in that it includes a plurality of segments, and is generated on a segment-by-segment basis. In some implementations, a first segment of the stream of NL based output is selected for inclusion in the stream of NL based output as a second segment (and any subsequent segment) is being generated to reduce latency in evaluating the NL based output as a whole prior to rendering thereof. In some versions of those implementations, the first segment is rendered as the second segment (and any subsequent segment) is being generated to further reduce latency in rendering thereof.

Abstract: A method for producing polyoxymethylene dimethyl ethers using fluidized bed reactor is provided. The fluidized bed reactor gives high conversion of feedstock during synthesis of polyoxymethylene dimethyl ethers. The product separation process includes pre-rectification, extractive rectification and vacuum rectification in series. In the pre-rectification process, the side-draw fraction PODE2 is recycled into the fluidized bed reactor, thus product distribution and selectivity to target components in the reactor can be improved. The extractive rectification process realizes coupling of neutralization, extraction, recovery of unconverted feedstock and products separation, thus significantly simplifies the process. The method for preparation of polyoxymethylene dimethyl ethers in this invention is simple, and has high conversion of feedstock, low energy cost and high selectivity to products.

Abstract: A method for producing polyoxymethylene dimethyl ethers using fluidized bed reactor is provided. The fluidized bed reactor gives high conversion of feedstock during synthesis of polyoxymethylene dimethyl ethers. The product separation process includes pre-rectification, extractive rectification and vacuum rectification in series. In the pre-rectification process, the side-draw fraction PODE2 is recycled into the fluidized bed reactor, thus product distribution and selectivity to target components in the reactor can be improved. The extractive rectification process realizes coupling of neutralization, extraction, recovery of unconverted feedstock and products separation, thus significantly simplifies the process. The method for preparation of polyoxymethylene dimethyl ethers in this invention is simple, and has high conversion of feedstock, low energy cost and high selectivity to products.