Abstract: A fully human antibody targeting GPRC5D and a chimeric antigen receptor (CAR) comprising the fully human antibody. A host cell expressing the CAR, such as a CAR-T cell. A use of the fully human antibody, the CAR, and the CAR-T cell in treatment of tumors (such as multiple myeloma).

Abstract: The present invention provides a polysubstituted nitrogen-containing heterocyclic derivative, a preparation method, and use thereof. In the present invention, the novel structure of the natural nitrogen-containing heterocyclic molecule is designed to obtain the polysubstituted nitrogen-containing heterocyclic derivative. The polysubstituted nitrogen-containing heterocyclic derivatives have obvious bactericidal activity, and some compounds have significant bactericidal activity against diseases such as E. carotovora, E. coli, and R. solanacearum, which can be widely applied in the comprehensive prevention and control of agricultural and forestry bacterial diseases. The bactericide obtained by mixing the polysubstituted nitrogen-containing heterocyclic derivative of the present invention with various adjuvants also have good bactericidal effects on E. coli, E. carotovora, R. solanacearum, etc.

Abstract: Strain of Bacillus thuringiensis novonest4 and applications thereof. The Bacillus thuringiensis is the Bacillus thuringiensis novonest4, with an Accession No. CCTCC NO: M2018443. The strain is firstly reported to have both the effect of preventing and controlling lepidoptera pests after foilar application and the effects of degrading carbendazim, promoting crop growth and increasing crop yield after soil application, and has wide application prospects in agricultural production.

Abstract: Strain of Bacillus thuringiensis novonest4 and applications thereof. The Bacillus thuringiensis is the Bacillus thuringiensis novonest4, with an Accession No. CCTCC NO: M2018443. The strain is firstly reported to have both the effect of preventing and controlling lepidoptera pests after foilar application and the effects of degrading carbendazim, promoting crop growth and increasing crop yield after soil application, and has wide application prospects in agricultural production.

Abstract: An integrated magnetic element includes a conductive base, a bobbin, a winding coil, a first magnetic core assembly and a second magnetic core assembly. The conductive base includes a first conductive unit including a plurality of first conductive winding parts, a second conductive unit including at least one second conductive winding part, and a connecting part. The bobbin includes a bobbin body, a winding section, a channel and a plurality of insertion slots. The first conductive winding parts are inserted into corresponding insertion slots of the bobbin. The first magnetic core assembly is sheathed around the bobbin and partially embedded into the channel of the bobbin and the first holes of the first conductive winding parts. The second magnetic core assembly is sheathed around the second conductive unit of the conductive base and partially embedded into the second hole of the second conductive winding part.

Abstract: An integrated magnetic element includes a conductive base, a bobbin, a winding coil, a first magnetic core assembly and a second magnetic core assembly. The conductive base includes a first conductive unit including a plurality of first conductive winding parts, a second conductive unit including at least one second conductive winding part, and a connecting part. The bobbin includes a bobbin body, a winding section, a channel and a plurality of insertion slots. The first conductive winding parts are inserted into corresponding insertion slots of the bobbin. The first magnetic core assembly is sheathed around the bobbin and partially embedded into the channel of the bobbin and the first holes of the first conductive winding parts. The second magnetic core assembly is sheathed around the second conductive unit of the conductive base and partially embedded into the second hole of the second conductive winding part.