Patents by Inventor Yao-Chang Xu

Yao-Chang Xu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Serotonin 5-HT.sub.1F agonists
    Patent number: 5792763
    Abstract: This invention provides novel 5-HT.sub.1F agonists of formula ##STR1## where X, Y, Z,and R are defined in the specification, which are useful for the prevention and treatment of migraine and associated disorders.
    Type: Grant
    Filed: September 26, 1997
    Date of Patent: August 11, 1998
    Assignee: Eli Lilly and Company
    Inventors: James E. Fritz, Stephen W. Kaldor, Sidney Xi Liang, Upinder Singh, Yao-Chang Xu
  • Antineoplastic heteronapthoquinones
    Patent number: 5736523
    Abstract: This invention relates to a naphthoquinone derivatives, to processes and to intermediates for preparing these derivatives, to pharmaceutical composition and to the use of these derivatives as antitumor agents in mammals.
    Type: Grant
    Filed: March 10, 1995
    Date of Patent: April 7, 1998
    Assignee: Biochem Pharma Inc.
    Inventors: Giorgio Attardo, Tibor Breining, Marc Courchesne, Serge Lamothe, Jean-Fran.cedilla.ois Lavallee, Dieu Nguyen, Rabindra Rej, Yves St-Denis, Wuyi Wang, Yao-Chang Xu, France Barbeau, Elaine Lebeau, Jean Louis Kraus
  • 6-substituted-1,2,3,4-tetrahydro-9H-carbazoles and 7-substituted-10H-cyclohepta ?7,6-B!indoles: New 5-HT.sub.1F agonists
    Patent number: 5708187
    Abstract: This invention provides novel 6-substituted-1,2,3,4-tetrahydro-9H-carbazoles and 7-substituted-10H-cyclohepta?7,6-b!indoles. These compounds are 5-HT.sub.1F agonists which are useful for the treatment of migraine and associated disorders.
    Type: Grant
    Filed: June 27, 1996
    Date of Patent: January 13, 1998
    Assignee: Eli Lilly and Company
    Inventors: Michael Edward Flaugh, Anton Daniel Kiefer, Jr., Clint Duane Walker, Yao-Chang Xu
  • Processes antineoplastic heteronaphthoquinones
    Patent number: 5606037
    Abstract: This invention relates to a naphthoquinone derivatives, to processes and to intermediates for preparing these derivatives, to pharmaceutical composition and to the use of these derivatives as antitumor agents in mammals.
    Type: Grant
    Filed: March 10, 1995
    Date of Patent: February 25, 1997
    Assignee: BioChem Pharma Inc.
    Inventors: Giorgio Attardo, Tibor Breining, Marc Courchesne, Serge Lamothe, Jean-Fran.cedilla.ois Lavall ee, Dieu Nguyen, Rabindra Rej, Yves St-Denis, Wuyi Wang, Yao-Chang Xu, France Barbeau, Elaine Lebeau, Jean L. Kraus
  • Heterocyclic anthracycline analogs
    Patent number: 5593970
    Abstract: Novel pyrano heterocyclic anthracycline derivatives are described, which are useful in the treatment of cancer and tumors, such as breast cancer, leukemia, lung cancer, colon cancer, ovarian cancer, renal cancer, and melanoma. As well, these compounds may be used ex vivo for the treatment of cancerous bone marrow before retransplanting said marrow in a patient. Pharmaceutical compositions and methods of preparing the compounds are also described.
    Type: Grant
    Filed: June 20, 1994
    Date of Patent: January 14, 1997
    Assignee: Biochem Pharma Inc.
    Inventors: Giorgio Attardo, Jean-Louis Kraus, Marc Courchesne, Serge Lamonthe, Jean-Fran.cedilla.ois Lavall ee, Elaine Lebeau, Dieu Nguyen, Rabindra Rej, Yves St-Denis, Wuyi Wang, Yao-Chang Xu, France Barbeau, Bernard Belleau, deceased