Patents by Inventor Yao JIANG

Yao JIANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12012442
    Abstract: Disclosed herein is an activatable fusion protein that includes, in an N- to C-terminal direction, an albumin, a matrix metalloproteinase-cleavable linker, and an immunoadhesin which includes a cytotoxic T lymphocyte-associated antigen-4 (CTLA4) having an N-terminal extracellular domain and an IgG Fc region, wherein the albumin is released from the activatable fusion protein in the presence of a matrix metalloproteinase that cleaves the cleavable linker, so that the N-terminal extracellular domain of the CTLA4 binds to CD80 or CD86. Also disclosed herein is use of the activatable fusion protein for suppressing a T cell-dependent immune response.
    Type: Grant
    Filed: April 19, 2021
    Date of Patent: June 18, 2024
    Assignee: NATIONAL YANG MING CHIAO TUNG UNIVERSITY
    Inventors: Shey-Cherng Tzou, Yu-Yuan Hsiao, Fu-Yao Jiang, Yan-Zhu Zhang, Chien-Yu Chou
  • Publication number: 20240156847
    Abstract: Use of baicalin in preparation of a medicament for resisting pseudorabies virus (PRV) and diseases caused thereby is provided. The present disclosure relates to the technical field of medicine. It is found for the first time in the present disclosure that the baicalin has anti-PRV activity, has no obvious toxicity to cells in the using concentration range of 31.25-125 ?M, and shows an obvious inhibitory effect on PRV replication and proliferation in the concentration range of 62.5-125 ?M. It can be foreseen that the baicalin can be developed as a safe and effective anti-PRV medicament, and a novel anti-PRV medicament under existing application conditions of the baicalin, with an excellent application prospect.
    Type: Application
    Filed: October 10, 2023
    Publication date: May 16, 2024
    Applicant: KEY LABORATORY OF ANIMAL IMMUNOLOGY, HAAS
    Inventors: Qingxia LU, Zhenhua GUO, Maoyang WENG, Qiaoge NIU, Qianyue JIN, Yao JIANG, Jifei YANG, Weitao XIE, Fengxia LV, Lingjuan LI
  • Patent number: 11973218
    Abstract: A novel positive electrode sheet, a secondary battery, a battery module, a battery pack and an electrical apparatus are described. The positive electrode sheet includes a positive electrode current collector and a positive electrode film layer with a single-layer structure or a multi-layer structure. When the positive electrode film layer is a single-layer structure, at least one of the positive electrode film layers comprises a first positive electrode active material and a second positive electrode active material; and/or, when the positive electrode film layer is a multi-layer structure, at least one layer of at least one of the positive electrode film layers comprises a first positive electrode active material and a second positive electrode active materials. The first positive electrode active material includes an inner core, a first cladding layer comprising crystalline pyrophosphates, a second cladding layer comprising crystalline phosphate, and a third cladding layer.
    Type: Grant
    Filed: October 16, 2023
    Date of Patent: April 30, 2024
    Assignee: CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED
    Inventors: Xiang Zhou, Baiqing Li, Jiang Liu, Yao Jiang, Xiaomei Liu
  • Publication number: 20240120480
    Abstract: A positive electrode active material includes a core containing Li1+xMn1yAyP1?zRzO4, a first coating layer covering the core and containing a crystalline pyrophosphate MaP2O7 and a crystalline oxide M?bOc, and a second coating layer covering the first coating layer.
    Type: Application
    Filed: December 2, 2023
    Publication date: April 11, 2024
    Inventors: Yao JIANG, Xinxin ZHANG, Chuying OUYANG, Bin DENG, Tianci YUAN, Zhiqiang WANG, Bo XU, Shangdong CHEN
  • Patent number: 11945559
    Abstract: The disclosed is a method for forecasting a demand load during navigation of a ship based on working condition classification. The method of the disclosure comprises: training historical data values by employing a least squares support vector machine to obtain a classification plane, classifying working conditions during the navigation into a fast-changing working condition and a stable working condition, and determining in real time a working condition type of the ship in an online stage. A method for forecasting a demand load by means of a Markov chain is employed for the stable working condition, and a method for forecasting a demand load by means of a radial basis function neural network optimized by a genetic algorithm is employed for the fast-changing working condition. A desirable forecasting effect can be achieved by selecting forecast models suitable for either type of working condition.
    Type: Grant
    Filed: July 2, 2021
    Date of Patent: April 2, 2024
    Inventors: Diju Gao, Yao Jiang, Wanneng Yu
  • Publication number: 20240064449
    Abstract: This application discloses a sound collecting method, an electronic device, and a system. The system includes a first electronic device, a left-ear TWS earphone, and a right-ear TWS earphone. In the method, microphones of the first electronic device, the left-ear TWS earphone, and the right-ear TWS earphone may form a first microphone array. When the first electronic device detects a user operation of starting video recording, the first microphone array performs sound collecting to obtain a joint microphone array signal. The first electronic device may perform noise reduction processing on the joint microphone array signal. According to the method, in a near field area of the first microphone array, a target sound signal can be enhanced, an ambient noise sound signal can be suppressed, and sound quality in a recorded video can be improved.
    Type: Application
    Filed: December 13, 2021
    Publication date: February 22, 2024
    Inventors: Kai Tao, Mingjie Yin, Qing Chang, Yao Jiang
  • Publication number: 20240047657
    Abstract: A novel positive electrode sheet, a secondary battery, a battery module, a battery pack and an electrical apparatus are described. The positive electrode sheet includes a positive electrode current collector and a positive electrode film layer with a single-layer structure or a multi-layer structure. When the positive electrode film layer is a single-layer structure, at least one of the positive electrode film layers comprises a first positive electrode active material and a second positive electrode active material; and/or, when the positive electrode film layer is a multi-layer structure, at least one layer of at least one of the positive electrode film layers comprises a first positive electrode active material and a second positive electrode active materials. The first positive electrode active material includes an inner core, a first cladding layer comprising crystalline pyrophosphates, a second cladding layer comprising crystalline phosphate, and a third cladding layer.
    Type: Application
    Filed: October 16, 2023
    Publication date: February 8, 2024
    Applicant: CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED
    Inventors: Xiang ZHOU, Baiqing LI, Jiang LIU, Yao JIANG, Xiaomei LIU
  • Patent number: 11888154
    Abstract: A positive electrode sheet may comprise a positive electrode current collector and a positive electrode film layer having a single-layer structure or a multi-layer structure provided on at least one surface thereof; when the positive electrode film layer is of a single-layer structure, at least one positive electrode film layer may comprise both a first positive electrode active material and a second positive electrode active material; and/or, when the positive electrode film layer is of a multi-layer structure, at least one layer of the at least one positive electrode film layer may comprise both a first positive electrode active material and a second positive electrode active material; the first positive electrode active material may comprises an inner core containing Li1+xMn1-yAyP1-zRzO4, a first coating layer containing pyrophosphate MP2O7 and phosphate XPO4 and covering the inner core, and a second coating layer containing carbon element and covering the first coating layer.
    Type: Grant
    Filed: June 20, 2023
    Date of Patent: January 30, 2024
    Assignee: CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED
    Inventors: Xiang Zhou, Jiang Liu, Baiqing Li, Yao Jiang, Xiaomei Liu
  • Patent number: 11882336
    Abstract: This application discloses techniques of implementing interactions among live streamers and viewers.
    Type: Grant
    Filed: August 4, 2022
    Date of Patent: January 23, 2024
    Assignee: SHANGHAI BILIBILI TECHNOLOGY CO., LTD.
    Inventors: Duona Zhou, Yao Jiang
  • Publication number: 20230378462
    Abstract: A positive electrode sheet, a secondary battery, a battery module, a battery pack and an electrical apparatus are described. The positive electrode sheet includes a positive electrode current collector and a positive electrode film layer arranged on at least one surface of the positive electrode current collector and having a single-layer or multi-layer structure. When the positive electrode film layer is of the single-layer structure, at least one positive electrode film layer comprises both a first positive electrode active material and a second positive electrode active material with a chemical formula of LiaAxMn1-yRyP1-zCzO4-nDn; and/or, when the positive electrode film layer is of the multi-layer structure, at least one layer of the at least one positive electrode film layer includes both a first and second positive electrode active material. The secondary battery made of the positive electrode sheet has high energy density and high battery cell rate performance.
    Type: Application
    Filed: August 2, 2023
    Publication date: November 23, 2023
    Applicant: CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED
    Inventors: Xiang ZHOU, Yao JIANG, Jiang LIU, Baiqing LI
  • Publication number: 20230361296
    Abstract: A positive electrode active material includes LiaAxMn1-yByP1-zCzO4-nDn. A includes one or more selected from group IA, group IIA, group IIIA, group IIB, group VB, and group VIB. B includes one or more selected from group IA, group IIA, group IIIA, group IVA, group VA, group IIB, group IVB, group VB, group VIB, and group VIII. C includes one or more selected from group IIIA, group IVA, group VA and group VIA. D includes one or more selected from group VIA and group VIIA. a is selected from 0.85 to 1.15. x is selected from 0 to 0.1. y is selected from 0.001 to 0.999. z is selected from 0 to 0.5. n is selected from 0 to 0.5.
    Type: Application
    Filed: July 13, 2023
    Publication date: November 9, 2023
    Inventors: Yao JIANG, Chuying OUYANG, Xinxin ZHANG, Bin DENG, Zhiqiang WANG, Tianci YUAN, Bo XU, Shangdong CHEN
  • Publication number: 20230352663
    Abstract: A positive electrode sheet may comprise a positive electrode current collector and a positive electrode film layer having a single-layer structure or a multi-layer structure provided on at least one surface thereof; when the positive electrode film layer is of a single-layer structure, at least one positive electrode film layer may comprise both a first positive electrode active material and a second positive electrode active material; and/or, when the positive electrode film layer is of a multi-layer structure, at least one layer of the at least one positive electrode film layer may comprise both a first positive electrode active material and a second positive electrode active material; the first positive electrode active material may comprises an inner core containing Li1+xMn1-yAyP1-zRzO4, a first coating layer containing pyrophosphate MP2O7 and phosphate XPO4 and covering the inner core, and a second coating layer containing carbon element and covering the first coating layer.
    Type: Application
    Filed: June 20, 2023
    Publication date: November 2, 2023
    Applicant: CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED
    Inventors: Xiang ZHOU, Jiang LIU, Baiqing LI, Yao JIANG, Xiaomei LIU
  • Patent number: 11760657
    Abstract: The present application discloses a positive electrode active material including a lithium nickel cobalt manganese oxide, the molar content of nickel in the lithium nickel cobalt manganese oxide accounts for 60%-90% of the total molar content of nickel, cobalt and manganese, and the lithium nickel cobalt manganese oxide has a layered crystal structure of a space group R 3m; a transition metal layer of the lithium nickel cobalt manganese oxide includes a doping element, and the local mass concentration of the doping element in particles of the positive electrode active material has a relative deviation of 20% or less; and in a differential scanning calorimetry spectrum of the positive electrode active material in a 78% delithiation state, an initial exothermic temperature of a main exothermic peak is 200° C. or more, and an integral area of the main exothermic peak is 100 J/g or less.
    Type: Grant
    Filed: February 15, 2023
    Date of Patent: September 19, 2023
    Assignee: Contemporary Amperex Technology Co., Limited
    Inventors: Shushi Dou, Chunhua Hu, Yao Jiang, Qi Wu, Jinhua He, Bin Deng
  • Patent number: 11695157
    Abstract: This application provides a lithium-ion battery and an apparatus. The lithium-ion battery includes an electrode assembly and an electrolyte. The electrode assembly includes a positive electrode plate, a negative electrode plate, and a separator. A positive active material of the positive electrode plate includes Lix1Coy1M1-y1O2-z1Qz1, where 0.5?x1?1.2, 0.8?y1?1.0, 0?z1?0.1, M is selected from one or more of Al, Ti, Zr, Y, and Mg, and Q is selected from one or more of F, Cl, and S. The electrolyte contains an additive A that is a polynitrile six-membered nitrogen-heterocyclic compound with a relatively low oxidation potential. The lithium-ion battery has superb cycle performance and storage performance, especially under high-temperature and high-voltage conditions.
    Type: Grant
    Filed: January 25, 2022
    Date of Patent: July 4, 2023
    Assignee: Contemporary Amperex Technology Co., Limited
    Inventors: Tiancheng Yi, Chunhua Hu, Shushi Dou, Yao Jiang, Chengdu Liang
  • Publication number: 20230202864
    Abstract: The present application discloses a positive electrode active material including a lithium nickel cobalt manganese oxide, the molar content of nickel in the lithium nickel cobalt manganese oxide accounts for 60%-90% of the total molar content of nickel, cobalt and manganese, and the lithium nickel cobalt manganese oxide has a layered crystal structure of a space group R 3m; a transition metal layer of the lithium nickel cobalt manganese oxide includes a doping element, and the local mass concentration of the doping element in particles of the positive electrode active material has a relative deviation of 20% or less; and in a differential scanning calorimetry spectrum of the positive electrode active material in a 78% delithiation state, an initial exothermic temperature of a main exothermic peak is 200° C. or more, and an integral area of the main exothermic peak is 100 J/g or less.
    Type: Application
    Filed: February 15, 2023
    Publication date: June 29, 2023
    Applicant: Contemporary Amperex Technology Co., Limited
    Inventors: Shushi Dou, Chunhua Hu, Yao Jiang, Qi Wu, Jinhua He, Bin Deng
  • Patent number: 11685746
    Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted bicyclic heteroaryl compounds of Formula (I), Formula (II), Formula (III), or Formula (IV), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
    Type: Grant
    Filed: June 25, 2019
    Date of Patent: June 27, 2023
    Assignee: PTC Therapeutics, Inc.
    Inventors: Guangming Chen, Anuradha Bhattacharyya, Yao Jiang, Gary Mitchell Karp, Jana Narasimhan, Anthony Turpoff, Nanjing Zhang
  • Patent number: 11613474
    Abstract: The present application discloses a positive electrode active material including a lithium nickel cobalt manganese oxide, the molar content of nickel in the lithium nickel cobalt manganese oxide accounts for 60%-90% of the total molar content of nickel, cobalt and manganese, and the lithium nickel cobalt manganese oxide has a layered crystal structure of a space group R 3m; a transition metal layer of the lithium nickel cobalt manganese oxide includes a doping element, and the local mass concentration of the doping element in particles of the positive electrode active material has a relative deviation of 20% or less; and in a differential scanning calorimetry spectrum of the positive electrode active material in a 78% delithiation state, an initial exothermic temperature of a main exothermic peak is 200° C. or more, and an integral area of the main exothermic peak is 100 J/g or less.
    Type: Grant
    Filed: March 1, 2022
    Date of Patent: March 28, 2023
    Assignee: Contemporary Amperex Technology Co., Limited
    Inventors: Shushi Dou, Chunhua Hu, Yao Jiang, Qi Wu, Jinhua He, Bin Deng
  • Patent number: 11581684
    Abstract: An electrical connector includes an elongate insulative housing defining a central slot extending along a longitudinal direction, and two rows of contacts disposed by two sides of the central slot. The housing forms a front receiving cavity to receive the corresponding mating tongue of the complementary connector, and a rear receiving cavity to receive the corresponding insulators wherein each insulator is integrally formed with each row of contacts via insert-molding for completing the whole contact module. Each grounding contact is equipped with the corresponding EMI absorber before being insert-molded within the insulator so as to have the corresponding EMI absorber also integrally formed with the insulator.
    Type: Grant
    Filed: December 28, 2020
    Date of Patent: February 14, 2023
    Assignees: FOXCONN (KUNSHAN) COMPUTER CONNECTOR CO., LTD., FOXCONN INTERCONNECT TECHNOLOGY LIMITED
    Inventors: Rui-Qin Wang, Zhan-Sheng Meng, Meng Liu, Yen-Chih Chang, Yu-San Hsiao, Shih-Wei Hsiao, Jhih-Yao Jiang
  • Publication number: 20220407059
    Abstract: This application discloses a positive electrode active material and a preparation method thereof, a positive electrode plate, a lithium-ion secondary battery, and a battery module, battery pack, and apparatus containing such lithium-ion secondary battery. The positive electrode active material includes bulk particles and an element M1-containing oxide coating layer applied on an exterior surface of each of the bulk particles. The bulk particle includes a nickel-containing lithium composite oxide. Bulk phases of the bulk particles are uniformly doped with element M2. A surface layer of the bulk particle is an exterior doped layer doped with element M3. Element M1 and element M3 are each independently selected from one or more of Mg, Al, Ca, Ce, Ti, Zr, Zn, Y, and B, and element M2 includes one or more of Si, Ti, Cr, Mo, V, Ge, Se, Zr, Nb, Ru, Rh, Pd, Sb, Te, Ce, and W.
    Type: Application
    Filed: February 25, 2022
    Publication date: December 22, 2022
    Applicant: CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED
    Inventors: Shushi DOU, Chunhua HU, Yao JIANG, Qi WU, Jinhua HE, Bin DENG
  • Publication number: 20220393236
    Abstract: The present application provides a lithium-ion battery and an apparatus, the lithium-ion battery includes an electrode assembly and an electrolyte. The electrode assembly includes a positive electrode sheet, a negative electrode sheet and a separation film. The positive active material in the positive electrode sheet includes Lix1Coy1M1-y1O2-z1Qz1, 0.5?x1?1.2, 0.8?y1<1.0, 0?z1?0.1, and M is selected from one of Al, Ti, Zr, Y, and Mg, and Q is selected from one or more of F, Cl, and S. The electrolyte contains an additive A and an additive B, the additive A is a polynitrile six-membered nitrogen-heterocyclic compound with a relatively low oxidation potential, and the additive B is an aliphatic dinitrile or polynitrile compound with a relatively high oxidation potential. The lithium-ion battery of the present application has superb cycle performance and storage performance, especially under high-temperature and high-voltage conditions.
    Type: Application
    Filed: March 17, 2022
    Publication date: December 8, 2022
    Applicant: Contemporary Amperex Technology Co., Limited
    Inventors: Tiancheng YI, Chunhua HU, Yao JIANG, Shushi DOU, Chengdu LIANG