Patents by Inventor Yao Shen

Yao Shen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12222550
    Abstract: A light scattering patch device and preparation method thereof is disclosed. The light scattering patch device is composed of a patch, an air gap, and a tapered optical fiber; the patch is a transparent patch; a refractive index of the patch is greater than a refractive index of a biological tissue; a tip, a tapered transition zone and a partial unstretched zone of the tapered optical fiber are embedded in the patch, and the air gap is formed between the tip and the tapered transition zone of the tapered optical fiber and the patch. The method of preparing the light scattering patch device comprises: first preparing the tapered optical fiber, then performing hydrophobic modification on the surface of the tapered optical fiber; placing the tapered optical fiber in an uncured polymer and curing the uncured polymer, and pulling the unstretched part; connecting the unstretched part of the tapered optical fiber.
    Type: Grant
    Filed: August 2, 2022
    Date of Patent: February 11, 2025
    Assignee: ZHEJIANG UNIVERSITY
    Inventors: Yang Zhu, Lei Zhang, Yao Tang, Kaicheng Deng, Liyin Shen
  • Patent number: 12218279
    Abstract: An optoelectronic device includes a first semiconductor layer, a second semiconductor layer and an active layer between the first semiconductor layer and the second semiconductor layer; a first insulating layer on the second semiconductor layer and including a plurality of first openings exposing the first semiconductor layer, wherein the first openings include a first group and a second group; a third electrode on the first insulating layer and including a first extended portion and a second extended portion, wherein the first extended portion and the second extended portion are respectively electrically connected to the first semiconductor layer through the first group of the first openings and the second group of the first openings, and wherein the number of the first group of the first openings is different from the number of the second group of the first openings; and a plurality of fourth electrodes on the second insulating layer and electrically connected to the second semiconductor layer, wherein in a
    Type: Grant
    Filed: January 11, 2024
    Date of Patent: February 4, 2025
    Assignee: EPISTAR CORPORATION
    Inventors: Chao-Hsing Chen, Jia-Kuen Wang, Chien-Chih Liao, Tzu-Yao Tseng, Tsun-Kai Ko, Chien-Fu Shen
  • Publication number: 20250038043
    Abstract: A passive device of a semiconductor substrate and method of making same. The passive device includes first and second top metal components on a substrate core having an insulator substrate. A passivation layer is formed over the top metal components and insulator substrate. A first conductive component is formed on the passivation layer electrically contacting the first top metal component, as well as a second conductive component that is formed on the passivation layer and electrically contacts the second top metal component. In addition, the device includes an insulator material that is formed over the first conductive component and the second conductive component. A cavity is defined by the insulator material between the first conductive component and the second conductive component. The device further includes an ABF plug component that is formed in the cavity between the first conductive component and the second conductive component.
    Type: Application
    Filed: July 25, 2023
    Publication date: January 30, 2025
    Inventors: Jui Shen Chang, Li-Hsien Huang, Chen-Nan Chiu, Yao-Chun Chuang, Yinlung Lu
  • Publication number: 20240044899
    Abstract: The present invention provides biomarkers for identifying patients suffering from diffuse large B-cell lymphoma who are likely to respond to therapy with fimepinostat. The invention further provides methods for treating such patients with fimepinostat.
    Type: Application
    Filed: July 27, 2023
    Publication date: February 8, 2024
    Inventors: Mariano J. ALVAREZ, Yao Shen
  • Patent number: 11613784
    Abstract: The present invention provides methods of detecting ultraviolet radiation (UVR)-induced skin damage in a subject. The method includes the steps of: a) obtaining a skin sample from the subject; b) analyzing expression levels in the skin sample of UVR-induced differentially expressed genes (DEGs) listed in Table 8 or a subset thereof; and c) comparing the expression levels of the UVR-induced DEGs to a control skin sample; wherein, when the expression levels of the UVR-induced DEGs in the skin sample is above or below the level of each of the UVR-induced DEGs in the control sample, the subject is identified as likely being afflicted with UVR-induced skin damage. Also provided are methods for measuring the effectiveness of a test agent in reducing ultraviolet radiation (UVR)-induced damage.
    Type: Grant
    Filed: March 16, 2017
    Date of Patent: March 28, 2023
    Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Liang Liu, Yao Shen
  • Publication number: 20220257514
    Abstract: The present invention relates to a monosaccharide-tagged nano-liposome, which is characterized that the targeting monosaccharide is conjugated to cholesterol and the monosaccharide-conjugated cholesterol is incorporate into the phospholipid bilayer. The nano-liposome of present invention exhibits the ability to carry the loaded drug to target cells, such as cancer cells and cancer stem cells in a tumor tissue, and may be internalized by endocytosis to produce direct cytotoxicity or suppress stemness gene expression, so as to avoid toxicity to normal cells and effectively improve the therapeutic effect of cancer clinical medication and radiation therapy.
    Type: Application
    Filed: May 23, 2019
    Publication date: August 18, 2022
    Inventors: Chun-Liang LO, Lu-Yi YU, Yao-An SHEN, Shang-Yu HUNG
  • Publication number: 20220178927
    Abstract: A method of treating a patient suffering from multiple myeloma, comprising determining a plurality of protein activity values in a subject suffering from multiple myeloma (MM), each protein activity value corresponding to one of a set of proteins in the subject; determining a classification of the subject as a responder or non-responder to a therapy by a compound represented by structural formula (1); and administering a therapeutically effective amount of the compound represented by structural formula (1) or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: March 27, 2020
    Publication date: June 9, 2022
    Inventors: Andrea Califano, Mariano Javier Alvarez, Yao Shen
  • Publication number: 20210054462
    Abstract: The present invention provides methods of detecting ultraviolet radiation (UVR)-induced skin damage in a subject. The method includes the steps of: a) obtaining a skin sample from the subject; b) analyzing expression levels in the skin sample of UVR-induced differentially expressed genes (DEGs) listed in Table 8 or a subset thereof; and c) comparing the expression levels of the UVR-induced DEGs to a control skin sample; wherein, when the expression levels of the UVR-induced DEGs in the skin sample is above or below the level of each of the UVR-induced DEGs in the control sample, the subject is identified as likely being afflicted with UVR-induced skin damage. Also provided are methods for measuring the effectiveness of a test agent in reducing ultraviolet radiation (UVR)-induced damage.
    Type: Application
    Filed: March 16, 2017
    Publication date: February 25, 2021
    Applicant: The Trustees of Columbia University in the City of New York
    Inventors: Liang LIU, Yao SHEN
  • Publication number: 20210002173
    Abstract: A hydrophobic admixture, for cementitious materials such as cement paste, mortar, and concrete, includes solid polymer particles with a coating of hydrophobic agent and surfactant. The solid polymer particles adhere to exterior surfaces of hydrated cement particles in the cement matrix. The solid polymer particles deliver the hydrophobic agent into the cement matrix which is hydrophilic. The hydrophobic agents are distributed uniformly throughout the cement matrix. The solid polymer particles can be crumb rubber particles derived from waste rubber tires, recycled plastics and similar solid materials. The hydrophobic liquid agent is derived from waste lubricant oil, spent motor oil, base oil, esters of fatty acids, vegetable oil and the like. Fine particles such as activated carbon, silica fume and spent catalyst can be employed to fill the large pores or cracks that develop in the cementitious matrix. The cured cementitious materials exhibit high contact angles and high compressive strengths.
    Type: Application
    Filed: December 10, 2019
    Publication date: January 7, 2021
    Applicant: AllNew Chemical Technology Company
    Inventors: Maw-Tien Lee, Zih-Yao Shen, Chi-Yao Chen, Fu-Ming Lee, John Lee
  • Patent number: 10882785
    Abstract: A hydrophobic admixture, for cementitious materials such as cement paste, mortar, and concrete, includes solid polymer particles with a coating of hydrophobic agent and surfactant. The solid polymer particles adhere to exterior surfaces of hydrated cement particles in the cement matrix. The solid polymer particles deliver the hydrophobic agent into the cement matrix which is hydrophilic. The hydrophobic agents are distributed uniformly throughout the cement matrix. The solid polymer particles can be crumb rubber particles derived from waste rubber tires, recycled plastics and similar solid materials. The hydrophobic liquid agent is derived from waste lubricant oil, spent motor oil, base oil, esters of fatty acids, vegetable oil and the like. Fine particles such as activated carbon, silica fume and spent catalyst can be employed to fill the large pores or cracks that develop in the cementitious matrix. The cured cementitious materials exhibit high contact angles and high compressive strengths.
    Type: Grant
    Filed: December 10, 2019
    Date of Patent: January 5, 2021
    Assignee: ALLNEW Chemical Technology Company
    Inventors: Maw-Tien Lee, Zih-Yao Shen, Chi-Yao Chen, Fu-Ming Lee, John Lee
  • Patent number: 10590038
    Abstract: A hydrophobic admixture, for cementitious materials such as cement paste, mortar, and concrete, includes solid polymer particles with a coating of hydrophobic agent and surfactant. The solid polymer particles adhere to exterior surfaces of hydrated cement particles in the cement matrix. The solid polymer particles deliver the hydrophobic agent into the cement matrix which is hydrophilic. The hydrophobic agents are distributed uniformly throughout the cement matrix. The solid polymer particles can be crumb rubber particles derived from waste rubber tires, recycled plastics and similar solid materials. The hydrophobic liquid agent is derived from waste lubricant oil, spent motor oil, base oil, esters of fatty acids, vegetable oil and the like. Fine particles such as activated carbon, silica fume and spent catalyst can be employed to fill the large pores or cracks that develop in the cementitious matrix. The cured cementitious materials exhibit high contact angles and high compressive strengths.
    Type: Grant
    Filed: July 1, 2019
    Date of Patent: March 17, 2020
    Inventors: Maw-Tien Lee, Zih-Yao Shen, Chi-Yao Chen, Fu-Ming Lee, John Lee
  • Patent number: 9955140
    Abstract: An initial candidate foreground region is identified within an infrared image that includes pixels exhibiting infrared intensity values within a pre-defined range. A depth of surfaces within the initial candidate foreground region is estimated based on infrared intensity values the pixels of the initial candidate foreground region. The initial candidate foreground region is expanded to an expanded candidate foreground region based on a body-model estimate. The body model estimate is seeded with one or more of the initial candidate foreground region, the depth of surfaces, and/or a face of a human subject identified by facial recognition. Each pixel of the infrared image is identified as either a foreground pixel or a background pixel based on a distance of that pixel relative to the expanded candidate foreground region. Pixels identified as background pixels may be modified within a corresponding visible light image.
    Type: Grant
    Filed: March 11, 2015
    Date of Patent: April 24, 2018
    Assignee: MICROSOFT TECHNOLOGY LICENSING, LLC
    Inventors: Christoph Rhemann, Emad Barsoum, Yao Shen, Simon P. Stachniak, Shahram Izadi
  • Patent number: 9496957
    Abstract: Embodiments of the present invention provide a method and an apparatus for allocating optical spectrum bandwidth resources. The method includes: first determine bandwidth of an OTUbase according to optical-layer frequency grid bandwidth and carrier spectrum efficiency; then construct an HO OTUflex according to bandwidth of customer service data and the bandwidth of the OTUbase, bandwidth of the HO OTUflex is a first integer multiple of the bandwidth of the OTUbase; map the customer service data into a payload area of the HO OTUflex and encapsulate overhead information; at last, modulate the HO OTUflex that carries the customer service data to a second integer number of optical channel carriers. The embodiments of the present invention apply to a scenario where customer service data is transported.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: November 15, 2016
    Assignee: Huawei Technologies Co., Ltd.
    Inventors: Wei Su, Chiwu Ding, Qiuyou Wu, Huaping Qing, Yao Shen, Hongli Jiang, Jianying Wei
  • Publication number: 20160269714
    Abstract: An initial candidate foreground region is identified within an infrared image that includes pixels exhibiting infrared intensity values within a pre-defined range. A depth of surfaces within the initial candidate foreground region is estimated based on infrared intensity values the pixels of the initial candidate foreground region. The initial candidate foreground region is expanded to an expanded candidate foreground region based on a body-model estimate. The body model estimate is seeded with one or more of the initial candidate foreground region, the depth of surfaces, and/or a face of a human subject identified by facial recognition. Each pixel of the infrared image is identified as either a foreground pixel or a background pixel based on a distance of that pixel relative to the expanded candidate foreground region. Pixels identified as background pixels may be modified within a corresponding visible light image.
    Type: Application
    Filed: March 11, 2015
    Publication date: September 15, 2016
    Inventors: Christoph Rhemann, Emad Barsoum, Yao Shen, Simon P. Stachniak, Shahram Izadi
  • Patent number: 9440278
    Abstract: Methods and apparatuses for roller hemming are disclosed herein. An example of a sheet metal roller hemming apparatus includes a first electrode to electrically connect to an electrical power supply and a sheet metal workpiece. The apparatus further includes a second electrode to electrically connect to the electrical power supply and the sheet metal workpiece to cause pulsed electric current to flow through a portion of the workpiece to locally increase formability in the portion of the workpiece. The apparatus still further includes a roller assembly to contact the workpiece to cause the workpiece to bend in the portion of the workpiece when the pulsed electric current is flowing through the portion of the workpiece, and to form a hem.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: September 13, 2016
    Assignees: GM Global Technologies Operations LLC, Shanghai Jiao Tong University
    Inventors: Jeff Wang, Xianghuai Dong, Yao Shen, Jun Chen
  • Patent number: 9352331
    Abstract: A high capacity magnetic filter separates diamagnetic and/or paramagnetic substances from fluid streams. Diamagnetic solid substances are magnetized under an external magnetic field through coordinated interaction of diamagnetic solid substances with an inducement paramagnetic material (IPM). The magnetic filter serves as a separation zone created by the presence of IPM and magnets that are shielded from the IPM by non-magnetic sleeves or partitions. The IPM in the void volume between the magnets affords large surface area onto which diamagnetic and paramagnetic materials can contact and be attracted to. The relative position and distance of the magnetic source, such a magnetic bar or electromagnet, to the solid mixture of diamagnetic and IPM are adjusted to induce sufficiently strong magnetism in the diamagnetic solids which causes the diamagnetic solids to be attracted by the magnetic field as well. Both diamagnetic and paramagnetic substances can be removed from a liquid or gas.
    Type: Grant
    Filed: September 26, 2015
    Date of Patent: May 31, 2016
    Assignee: ALLNEW Chemical Technology Company
    Inventors: Maw-Tien Lee, Fu-Ming Lee, Zih-Yao Shen, Shou-Ming Lee, Ray-Lung Lin, Chun-Lung Wu, Wei-Chih Hung
  • Publication number: 20150104178
    Abstract: Embodiments of the present invention provide a method and an apparatus for allocating optical spectrum bandwidth resources. The method includes: first determine bandwidth of an OTUbase according to optical-layer frequency grid bandwidth and carrier spectrum efficiency; then construct an HO OTUflex according to bandwidth of customer service data and the bandwidth of the OTUbase, bandwidth of the HO OTUflex is a first integer multiple of the bandwidth of the OTUbase; map the customer service data into a payload area of the HO OTUflex and encapsulate overhead information; at last, modulate the HO OTUflex that carries the customer service data to a second integer number of optical channel carriers. The embodiments of the present invention apply to a scenario where customer service data is transported.
    Type: Application
    Filed: December 17, 2014
    Publication date: April 16, 2015
    Inventors: Wei SU, Chiwu DING, Qiuyou WU, Huaping QING, Yao SHEN, Hongli JIANG, Jianying WEI
  • Patent number: 8787406
    Abstract: A method and apparatus for distributing and receiving high-speed Ethernet Media Independent Interface (MII) blocks are provided to moderate the increase of control lines with the increase of the bit width and to simplify the block types in the coding process of the Physical Coding Sublayer (PCS). The technical solution disclosed herein includes: processing received Media Access Control (MAC) layer data, and adjusting distribution of control characters to generate a 64-bit block; obtaining a control signal code of the 64-bit block according to the relation between the form of the 64-bit block and the control signal code; and binding each 64-bit block to the corresponding control signal code respectively, and sending bound data over a separate channel.
    Type: Grant
    Filed: July 7, 2009
    Date of Patent: July 22, 2014
    Assignee: Huawei Technologies Co., Ltd.
    Inventors: Yao Shen, Li Zeng, Chiwu Ding
  • Publication number: 20140150514
    Abstract: Methods and apparatuses for roller hemming are disclosed herein. An example of a sheet metal roller hemming apparatus includes a first electrode to electrically connect to an electrical power supply and a sheet metal workpiece. The apparatus further includes a second electrode to electrically connect to the electrical power supply and the sheet metal workpiece to cause pulsed electric current to flow through a portion of the workpiece to locally increase formability in the portion of the workpiece. The apparatus still further includes a roller assembly to contact the workpiece to cause the workpiece to bend in the portion of the workpiece when the pulsed electric current is flowing through the portion of the workpiece, and to form a hem.
    Type: Application
    Filed: March 12, 2013
    Publication date: June 5, 2014
    Applicants: SHANGHAI JIAO TONG UNIVERSITY, GM GLOBAL TECHNOLOGY OPERATIONS LLC
    Inventors: Jeff Wang, Xianghuai Dong, Yao Shen, Jun Chen
  • Publication number: 20110044686
    Abstract: A method and a device for mapping and demapping a client signal are provided. The method for mapping a client signal includes: dividing a part or all of a payload area of an Optical Channel Payload Unit (OPU) or Optical channel Data Tributary Unit (ODTU) into several sub-blocks, in which the sub-blocks have a size of N bytes, and N is greater than or equal to 1; and mapping a client signal to be transported to the sub-blocks of the payload area with an N-byte granularity. In the technical solutions, when the client signal is mapped, block mapping of the client signal is performed by using a mapping granularity of a block, so that the complexity of the mapping process of the client signal can be reduced, thereby meeting requirements of multi-rate services.
    Type: Application
    Filed: November 8, 2010
    Publication date: February 24, 2011
    Applicant: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Qiuyou WU, Yao SHEN