Patents by Inventor Yao Shen
Yao Shen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12222550Abstract: A light scattering patch device and preparation method thereof is disclosed. The light scattering patch device is composed of a patch, an air gap, and a tapered optical fiber; the patch is a transparent patch; a refractive index of the patch is greater than a refractive index of a biological tissue; a tip, a tapered transition zone and a partial unstretched zone of the tapered optical fiber are embedded in the patch, and the air gap is formed between the tip and the tapered transition zone of the tapered optical fiber and the patch. The method of preparing the light scattering patch device comprises: first preparing the tapered optical fiber, then performing hydrophobic modification on the surface of the tapered optical fiber; placing the tapered optical fiber in an uncured polymer and curing the uncured polymer, and pulling the unstretched part; connecting the unstretched part of the tapered optical fiber.Type: GrantFiled: August 2, 2022Date of Patent: February 11, 2025Assignee: ZHEJIANG UNIVERSITYInventors: Yang Zhu, Lei Zhang, Yao Tang, Kaicheng Deng, Liyin Shen
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Patent number: 12218279Abstract: An optoelectronic device includes a first semiconductor layer, a second semiconductor layer and an active layer between the first semiconductor layer and the second semiconductor layer; a first insulating layer on the second semiconductor layer and including a plurality of first openings exposing the first semiconductor layer, wherein the first openings include a first group and a second group; a third electrode on the first insulating layer and including a first extended portion and a second extended portion, wherein the first extended portion and the second extended portion are respectively electrically connected to the first semiconductor layer through the first group of the first openings and the second group of the first openings, and wherein the number of the first group of the first openings is different from the number of the second group of the first openings; and a plurality of fourth electrodes on the second insulating layer and electrically connected to the second semiconductor layer, wherein in aType: GrantFiled: January 11, 2024Date of Patent: February 4, 2025Assignee: EPISTAR CORPORATIONInventors: Chao-Hsing Chen, Jia-Kuen Wang, Chien-Chih Liao, Tzu-Yao Tseng, Tsun-Kai Ko, Chien-Fu Shen
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Publication number: 20250038043Abstract: A passive device of a semiconductor substrate and method of making same. The passive device includes first and second top metal components on a substrate core having an insulator substrate. A passivation layer is formed over the top metal components and insulator substrate. A first conductive component is formed on the passivation layer electrically contacting the first top metal component, as well as a second conductive component that is formed on the passivation layer and electrically contacts the second top metal component. In addition, the device includes an insulator material that is formed over the first conductive component and the second conductive component. A cavity is defined by the insulator material between the first conductive component and the second conductive component. The device further includes an ABF plug component that is formed in the cavity between the first conductive component and the second conductive component.Type: ApplicationFiled: July 25, 2023Publication date: January 30, 2025Inventors: Jui Shen Chang, Li-Hsien Huang, Chen-Nan Chiu, Yao-Chun Chuang, Yinlung Lu
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Publication number: 20240044899Abstract: The present invention provides biomarkers for identifying patients suffering from diffuse large B-cell lymphoma who are likely to respond to therapy with fimepinostat. The invention further provides methods for treating such patients with fimepinostat.Type: ApplicationFiled: July 27, 2023Publication date: February 8, 2024Inventors: Mariano J. ALVAREZ, Yao Shen
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Patent number: 11613784Abstract: The present invention provides methods of detecting ultraviolet radiation (UVR)-induced skin damage in a subject. The method includes the steps of: a) obtaining a skin sample from the subject; b) analyzing expression levels in the skin sample of UVR-induced differentially expressed genes (DEGs) listed in Table 8 or a subset thereof; and c) comparing the expression levels of the UVR-induced DEGs to a control skin sample; wherein, when the expression levels of the UVR-induced DEGs in the skin sample is above or below the level of each of the UVR-induced DEGs in the control sample, the subject is identified as likely being afflicted with UVR-induced skin damage. Also provided are methods for measuring the effectiveness of a test agent in reducing ultraviolet radiation (UVR)-induced damage.Type: GrantFiled: March 16, 2017Date of Patent: March 28, 2023Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORKInventors: Liang Liu, Yao Shen
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Publication number: 20220257514Abstract: The present invention relates to a monosaccharide-tagged nano-liposome, which is characterized that the targeting monosaccharide is conjugated to cholesterol and the monosaccharide-conjugated cholesterol is incorporate into the phospholipid bilayer. The nano-liposome of present invention exhibits the ability to carry the loaded drug to target cells, such as cancer cells and cancer stem cells in a tumor tissue, and may be internalized by endocytosis to produce direct cytotoxicity or suppress stemness gene expression, so as to avoid toxicity to normal cells and effectively improve the therapeutic effect of cancer clinical medication and radiation therapy.Type: ApplicationFiled: May 23, 2019Publication date: August 18, 2022Inventors: Chun-Liang LO, Lu-Yi YU, Yao-An SHEN, Shang-Yu HUNG
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Publication number: 20220178927Abstract: A method of treating a patient suffering from multiple myeloma, comprising determining a plurality of protein activity values in a subject suffering from multiple myeloma (MM), each protein activity value corresponding to one of a set of proteins in the subject; determining a classification of the subject as a responder or non-responder to a therapy by a compound represented by structural formula (1); and administering a therapeutically effective amount of the compound represented by structural formula (1) or a pharmaceutically acceptable salt thereof.Type: ApplicationFiled: March 27, 2020Publication date: June 9, 2022Inventors: Andrea Califano, Mariano Javier Alvarez, Yao Shen
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Publication number: 20210054462Abstract: The present invention provides methods of detecting ultraviolet radiation (UVR)-induced skin damage in a subject. The method includes the steps of: a) obtaining a skin sample from the subject; b) analyzing expression levels in the skin sample of UVR-induced differentially expressed genes (DEGs) listed in Table 8 or a subset thereof; and c) comparing the expression levels of the UVR-induced DEGs to a control skin sample; wherein, when the expression levels of the UVR-induced DEGs in the skin sample is above or below the level of each of the UVR-induced DEGs in the control sample, the subject is identified as likely being afflicted with UVR-induced skin damage. Also provided are methods for measuring the effectiveness of a test agent in reducing ultraviolet radiation (UVR)-induced damage.Type: ApplicationFiled: March 16, 2017Publication date: February 25, 2021Applicant: The Trustees of Columbia University in the City of New YorkInventors: Liang LIU, Yao SHEN
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Publication number: 20210002173Abstract: A hydrophobic admixture, for cementitious materials such as cement paste, mortar, and concrete, includes solid polymer particles with a coating of hydrophobic agent and surfactant. The solid polymer particles adhere to exterior surfaces of hydrated cement particles in the cement matrix. The solid polymer particles deliver the hydrophobic agent into the cement matrix which is hydrophilic. The hydrophobic agents are distributed uniformly throughout the cement matrix. The solid polymer particles can be crumb rubber particles derived from waste rubber tires, recycled plastics and similar solid materials. The hydrophobic liquid agent is derived from waste lubricant oil, spent motor oil, base oil, esters of fatty acids, vegetable oil and the like. Fine particles such as activated carbon, silica fume and spent catalyst can be employed to fill the large pores or cracks that develop in the cementitious matrix. The cured cementitious materials exhibit high contact angles and high compressive strengths.Type: ApplicationFiled: December 10, 2019Publication date: January 7, 2021Applicant: AllNew Chemical Technology CompanyInventors: Maw-Tien Lee, Zih-Yao Shen, Chi-Yao Chen, Fu-Ming Lee, John Lee
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Patent number: 10882785Abstract: A hydrophobic admixture, for cementitious materials such as cement paste, mortar, and concrete, includes solid polymer particles with a coating of hydrophobic agent and surfactant. The solid polymer particles adhere to exterior surfaces of hydrated cement particles in the cement matrix. The solid polymer particles deliver the hydrophobic agent into the cement matrix which is hydrophilic. The hydrophobic agents are distributed uniformly throughout the cement matrix. The solid polymer particles can be crumb rubber particles derived from waste rubber tires, recycled plastics and similar solid materials. The hydrophobic liquid agent is derived from waste lubricant oil, spent motor oil, base oil, esters of fatty acids, vegetable oil and the like. Fine particles such as activated carbon, silica fume and spent catalyst can be employed to fill the large pores or cracks that develop in the cementitious matrix. The cured cementitious materials exhibit high contact angles and high compressive strengths.Type: GrantFiled: December 10, 2019Date of Patent: January 5, 2021Assignee: ALLNEW Chemical Technology CompanyInventors: Maw-Tien Lee, Zih-Yao Shen, Chi-Yao Chen, Fu-Ming Lee, John Lee
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Patent number: 10590038Abstract: A hydrophobic admixture, for cementitious materials such as cement paste, mortar, and concrete, includes solid polymer particles with a coating of hydrophobic agent and surfactant. The solid polymer particles adhere to exterior surfaces of hydrated cement particles in the cement matrix. The solid polymer particles deliver the hydrophobic agent into the cement matrix which is hydrophilic. The hydrophobic agents are distributed uniformly throughout the cement matrix. The solid polymer particles can be crumb rubber particles derived from waste rubber tires, recycled plastics and similar solid materials. The hydrophobic liquid agent is derived from waste lubricant oil, spent motor oil, base oil, esters of fatty acids, vegetable oil and the like. Fine particles such as activated carbon, silica fume and spent catalyst can be employed to fill the large pores or cracks that develop in the cementitious matrix. The cured cementitious materials exhibit high contact angles and high compressive strengths.Type: GrantFiled: July 1, 2019Date of Patent: March 17, 2020Inventors: Maw-Tien Lee, Zih-Yao Shen, Chi-Yao Chen, Fu-Ming Lee, John Lee
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Patent number: 9955140Abstract: An initial candidate foreground region is identified within an infrared image that includes pixels exhibiting infrared intensity values within a pre-defined range. A depth of surfaces within the initial candidate foreground region is estimated based on infrared intensity values the pixels of the initial candidate foreground region. The initial candidate foreground region is expanded to an expanded candidate foreground region based on a body-model estimate. The body model estimate is seeded with one or more of the initial candidate foreground region, the depth of surfaces, and/or a face of a human subject identified by facial recognition. Each pixel of the infrared image is identified as either a foreground pixel or a background pixel based on a distance of that pixel relative to the expanded candidate foreground region. Pixels identified as background pixels may be modified within a corresponding visible light image.Type: GrantFiled: March 11, 2015Date of Patent: April 24, 2018Assignee: MICROSOFT TECHNOLOGY LICENSING, LLCInventors: Christoph Rhemann, Emad Barsoum, Yao Shen, Simon P. Stachniak, Shahram Izadi
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Patent number: 9496957Abstract: Embodiments of the present invention provide a method and an apparatus for allocating optical spectrum bandwidth resources. The method includes: first determine bandwidth of an OTUbase according to optical-layer frequency grid bandwidth and carrier spectrum efficiency; then construct an HO OTUflex according to bandwidth of customer service data and the bandwidth of the OTUbase, bandwidth of the HO OTUflex is a first integer multiple of the bandwidth of the OTUbase; map the customer service data into a payload area of the HO OTUflex and encapsulate overhead information; at last, modulate the HO OTUflex that carries the customer service data to a second integer number of optical channel carriers. The embodiments of the present invention apply to a scenario where customer service data is transported.Type: GrantFiled: December 17, 2014Date of Patent: November 15, 2016Assignee: Huawei Technologies Co., Ltd.Inventors: Wei Su, Chiwu Ding, Qiuyou Wu, Huaping Qing, Yao Shen, Hongli Jiang, Jianying Wei
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Publication number: 20160269714Abstract: An initial candidate foreground region is identified within an infrared image that includes pixels exhibiting infrared intensity values within a pre-defined range. A depth of surfaces within the initial candidate foreground region is estimated based on infrared intensity values the pixels of the initial candidate foreground region. The initial candidate foreground region is expanded to an expanded candidate foreground region based on a body-model estimate. The body model estimate is seeded with one or more of the initial candidate foreground region, the depth of surfaces, and/or a face of a human subject identified by facial recognition. Each pixel of the infrared image is identified as either a foreground pixel or a background pixel based on a distance of that pixel relative to the expanded candidate foreground region. Pixels identified as background pixels may be modified within a corresponding visible light image.Type: ApplicationFiled: March 11, 2015Publication date: September 15, 2016Inventors: Christoph Rhemann, Emad Barsoum, Yao Shen, Simon P. Stachniak, Shahram Izadi
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Patent number: 9440278Abstract: Methods and apparatuses for roller hemming are disclosed herein. An example of a sheet metal roller hemming apparatus includes a first electrode to electrically connect to an electrical power supply and a sheet metal workpiece. The apparatus further includes a second electrode to electrically connect to the electrical power supply and the sheet metal workpiece to cause pulsed electric current to flow through a portion of the workpiece to locally increase formability in the portion of the workpiece. The apparatus still further includes a roller assembly to contact the workpiece to cause the workpiece to bend in the portion of the workpiece when the pulsed electric current is flowing through the portion of the workpiece, and to form a hem.Type: GrantFiled: March 12, 2013Date of Patent: September 13, 2016Assignees: GM Global Technologies Operations LLC, Shanghai Jiao Tong UniversityInventors: Jeff Wang, Xianghuai Dong, Yao Shen, Jun Chen
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Patent number: 9352331Abstract: A high capacity magnetic filter separates diamagnetic and/or paramagnetic substances from fluid streams. Diamagnetic solid substances are magnetized under an external magnetic field through coordinated interaction of diamagnetic solid substances with an inducement paramagnetic material (IPM). The magnetic filter serves as a separation zone created by the presence of IPM and magnets that are shielded from the IPM by non-magnetic sleeves or partitions. The IPM in the void volume between the magnets affords large surface area onto which diamagnetic and paramagnetic materials can contact and be attracted to. The relative position and distance of the magnetic source, such a magnetic bar or electromagnet, to the solid mixture of diamagnetic and IPM are adjusted to induce sufficiently strong magnetism in the diamagnetic solids which causes the diamagnetic solids to be attracted by the magnetic field as well. Both diamagnetic and paramagnetic substances can be removed from a liquid or gas.Type: GrantFiled: September 26, 2015Date of Patent: May 31, 2016Assignee: ALLNEW Chemical Technology CompanyInventors: Maw-Tien Lee, Fu-Ming Lee, Zih-Yao Shen, Shou-Ming Lee, Ray-Lung Lin, Chun-Lung Wu, Wei-Chih Hung
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Publication number: 20150104178Abstract: Embodiments of the present invention provide a method and an apparatus for allocating optical spectrum bandwidth resources. The method includes: first determine bandwidth of an OTUbase according to optical-layer frequency grid bandwidth and carrier spectrum efficiency; then construct an HO OTUflex according to bandwidth of customer service data and the bandwidth of the OTUbase, bandwidth of the HO OTUflex is a first integer multiple of the bandwidth of the OTUbase; map the customer service data into a payload area of the HO OTUflex and encapsulate overhead information; at last, modulate the HO OTUflex that carries the customer service data to a second integer number of optical channel carriers. The embodiments of the present invention apply to a scenario where customer service data is transported.Type: ApplicationFiled: December 17, 2014Publication date: April 16, 2015Inventors: Wei SU, Chiwu DING, Qiuyou WU, Huaping QING, Yao SHEN, Hongli JIANG, Jianying WEI
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Patent number: 8787406Abstract: A method and apparatus for distributing and receiving high-speed Ethernet Media Independent Interface (MII) blocks are provided to moderate the increase of control lines with the increase of the bit width and to simplify the block types in the coding process of the Physical Coding Sublayer (PCS). The technical solution disclosed herein includes: processing received Media Access Control (MAC) layer data, and adjusting distribution of control characters to generate a 64-bit block; obtaining a control signal code of the 64-bit block according to the relation between the form of the 64-bit block and the control signal code; and binding each 64-bit block to the corresponding control signal code respectively, and sending bound data over a separate channel.Type: GrantFiled: July 7, 2009Date of Patent: July 22, 2014Assignee: Huawei Technologies Co., Ltd.Inventors: Yao Shen, Li Zeng, Chiwu Ding
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Publication number: 20140150514Abstract: Methods and apparatuses for roller hemming are disclosed herein. An example of a sheet metal roller hemming apparatus includes a first electrode to electrically connect to an electrical power supply and a sheet metal workpiece. The apparatus further includes a second electrode to electrically connect to the electrical power supply and the sheet metal workpiece to cause pulsed electric current to flow through a portion of the workpiece to locally increase formability in the portion of the workpiece. The apparatus still further includes a roller assembly to contact the workpiece to cause the workpiece to bend in the portion of the workpiece when the pulsed electric current is flowing through the portion of the workpiece, and to form a hem.Type: ApplicationFiled: March 12, 2013Publication date: June 5, 2014Applicants: SHANGHAI JIAO TONG UNIVERSITY, GM GLOBAL TECHNOLOGY OPERATIONS LLCInventors: Jeff Wang, Xianghuai Dong, Yao Shen, Jun Chen
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Publication number: 20110044686Abstract: A method and a device for mapping and demapping a client signal are provided. The method for mapping a client signal includes: dividing a part or all of a payload area of an Optical Channel Payload Unit (OPU) or Optical channel Data Tributary Unit (ODTU) into several sub-blocks, in which the sub-blocks have a size of N bytes, and N is greater than or equal to 1; and mapping a client signal to be transported to the sub-blocks of the payload area with an N-byte granularity. In the technical solutions, when the client signal is mapped, block mapping of the client signal is performed by using a mapping granularity of a block, so that the complexity of the mapping process of the client signal can be reduced, thereby meeting requirements of multi-rate services.Type: ApplicationFiled: November 8, 2010Publication date: February 24, 2011Applicant: HUAWEI TECHNOLOGIES CO., LTD.Inventors: Qiuyou WU, Yao SHEN