Abstract: A compound represented by general formula (I) or a stereoisomer, tautomer, deuterated substance, solvate, prodrug, metabolite, pharmaceutically acceptable salt or co-crystal thereof, an intermediate thereof and a preparation method therefor, as well as an application in preparation of a drug for treating diabetes.

Abstract: Disclosed herein is a method for eccentricity correction. This method may dispose a downhole tool into a borehole. The downhole tool may comprise a measuring assembly that has at least one transducer, determining a beam pattern from the at least one transducer, determining a center of the measurement assembly in the borehole with the beam pattern, calculating a beam pattern factor with at least the beam pattern, calculating an angle factor with at least the beam pattern, calculating an eccentricity factor with at least the beam pattern factor and the angle factor, and creating an eccentricity corrected image with at least the eccentricity factor.

Abstract: The disclosure provides a LED device, a backlight module and a display device. The LED device includes: a bracket structure and a chip, the bracket structure having a cup cavity and the chip being mounted in the cup cavity; a packaging structure, the packaging structure being provided on the bracket structure in a covering manner to seal the cup cavity and an upper surface, far away from the cup cavity, of the packaging structure forming an emergent surface; and a reflective shielding layer, the reflective shielding layer being provided on the packaging structure and the reflective shielding layer being at a central position of the emergent surface and covering part of the emergent surface. According to the disclosure, the problem in the related art that it is impossible to consider both a good color saturation and brightness contrast of a display of a display device is solved.

Abstract: The disclosure provides a LED device, a backlight module and a display device. The LED device includes: a bracket structure and a chip, the bracket structure having a cup cavity and the chip being mounted in the cup cavity; a packaging structure, the packaging structure being provided on the bracket structure in a covering manner to seal the cup cavity and an upper surface, far away from the cup cavity, of the packaging structure forming an emergent surface; and a reflective shielding layer, the reflective shielding layer being provided on the packaging structure and the reflective shielding layer being at a central position of the emergent surface and covering part of the emergent surface. According to the disclosure, the problem in the related art that it is impossible to consider both a good color saturation and brightness contrast of a display of a display device is solved.

Abstract: A particle manipulation system and a projection device are provided. The projection device includes an image source and a projection lens. The image source provides an image beam. The projection lens is disposed on a light path of the image beam and includes a zoom lens set and a focusing lens set. The zoom lens set is disposed on the light path of the image beam from the image source and includes at least two lens groups disposed in sequence on the light path of the image beam. The focusing lens set is disposed on the light path of the image beam. The zoom lens set is disposed between the image source and the focusing lens set. A photoconductor chip is disposed on the light path of the image beam from the projection lens.

Abstract: An optically-induced dielectrophoresis device includes a first substrate, a first conductive layer, a first patterned photoconductor layer, a first patterned layer, a second substrate, a second conductive layer, and a spacer. The first conductive layer is disposed on the first substrate. The first patterned photoconductor layer is disposed on the first conductive layer. The first patterned layer is disposed on the first conductive layer. The first patterned photoconductor layer and the first patterned layer are distributed alternately over the first conductive layer. Resistivity of the first patterned photoconductor layer is not equal to resistivity of the first patterned layer. At least one of the first substrate and the second substrate is pervious to a light. The second conductive layer is disposed on the second substrate and between the first substrate and the second substrate. The spacer connects the first substrate and the second substrate.

Abstract: A carrier with the optical registration function is disclosed. The carrier allows the registration of inspected results of the sampling images of the sample to the corresponding address codes of the address coding site of the carrier.

Abstract: A particle manipulation system and a projection device are provided. The projection device includes an image source and a projection lens. The image source provides an image beam. The projection lens is disposed on a light path of the image beam and includes a zoom lens set and a focusing lens set. The zoom lens set is disposed on the light path of the image beam from the image source and includes at least two lens groups disposed in sequence on the light path of the image beam. The focusing lens set is disposed on the light path of the image beam. The zoom lens set is disposed between the image source and the focusing lens set. A photoconductor chip is disposed on the light path of the image beam from the projection lens.

Abstract: A retinal prosthesis including a microelectrode array, a polymer layer and a layer of bioactive molecule is provided. The microelectrode includes a plurality of microelectrodes. The polymer layer partly encapsulates the microelectrode array, in which the microelectrodes are exposed on the surface of the polymer layer. The layer of bioactive molecules is immobilized on the surface of the microelectrode.

Abstract: An optically-induced dielectrophoresis device includes a first substrate, a first conductive layer, a first patterned photoconductor layer, a first patterned layer, a second substrate, a second conductive layer, and a spacer. The first conductive layer is disposed on the first substrate. The first patterned photoconductor layer is disposed on the first conductive layer. The first patterned layer is disposed on the first conductive layer. The first patterned photoconductor layer and the first patterned layer are distributed alternately over the first conductive layer. Resistivity of the first patterned photoconductor layer is not equal to resistivity of the first patterned layer. At least one of the first substrate and the second substrate is pervious to a light. The second conductive layer is disposed on the second substrate and between the first substrate and the second substrate. The spacer connects the first substrate and the second substrate.

Abstract: A carrier with the optical registration function is disclosed. The carrier allows the registration of inspected results of the sampling images of the sample to the corresponding address codes of the address coding site of the carrier.

Abstract: A method for manufacturing a bioabsorbable stent and an apparatus for doing the same are disclosed. The method includes providing a polymer resin, melting the polymer resin to form a molten hollow parison, cooling the molten hollow parison to form a hot hollow parison, elongating the hot hollow parison, expanding the hot hollow parison by feeding a compressed gas into the hot hollow parison to form a stent preform, and patterning the stent preform to form a bioabsorbable stent.

Abstract: A fluidic device includes a first reservoir to receive a first fluid, a second reservoir to receive a second fluid, and a main channel coupled to the first and second reservoirs through one or more branch channels. A first one-use pump generates a pressure difference to move one or both of the first and second fluids when a container in the first one-use pump is broken. A second one-use pump generates a pressure difference to move one or both of the first and second fluids when a container in the second one-use pump is broken.

Abstract: A fluidic device for performing assays can include control components such as vacuum pumps, gas pumps, “broken open valves,” and “self-close valves” for controlling the flow of fluids in the fluidic device. The vacuum pump can be used to pull a fluid in a specific direction in a channel, and the gas pump can be used to push a fluid in a specific direction in a channel. The broken open valve can be used to connect two separate regions at the control of a user, and the self-close valve can be used to automatically seal off a channel after passage of a fluid. The vacuum pumps, gas pumps, broken open valves, and self close valves can be made small in volume so that the fluidic device can be made as a small and portable device.

Abstract: A fluidic device is provided for sealing a proper amount of fluid with a brittle material. By moving an adsorbate through an external adsorption force, the brittle material for pre-sealing is broken, and the fluid flows out to interact with the external environment to generate a pump reaction. In addition, the invention may also be used for storing a liquid reagent in a device for a long time. Thereby, the fluidic device can be made small and portable.

Abstract: A fluidic device includes a first material defining a first region, a second material defining a second region that is separated from the first region, and a connector coupled between the first region and the second region. The connector includes a brittle material and has an open end and a closed end, the open end being disposed in the second region, the closed end being disposed in the first region. The first region is closed off from the second region by the closed end of the connector. The connector is configured such that when the closed end of the connector is broken, the connector defines a passage from the first region to the second region.

Abstract: A fluidic device is provided for sealing a proper amount of fluid with a brittle material. By moving an adsorbate through an external adsorption force, the brittle material for pre-sealing is broken, and the fluid flows out to interact with the external environment to generate a pump reaction. In addition, the invention may also be used for storing a liquid reagent in a device for a long time. Thereby, the fluidic device can be made small and portable.

Abstract: A method of manufacturing a microfluidic device is described. A substrate having at least one device thereon is provided, wherein the device includes at least one channel. Next, a region beside the channel is heated, and then the substrate is pulled to neck the region such that at least one capillary connecting with the channel is formed. The present invention also provides a microfluidic device including a substrate and at least one capillary. In particular, the substrate has at least one device thereon, and the device has at least one channel. The capillary is connected with the channel, wherein the substrate and the capillary are a unity structure such that the interface between the capillary and the channel is dead-volume free.

Abstract: A fluidic device for performing assays can include control components such as vacuum pumps, gas pumps, “broken open valves,” and “self-close valves” for controlling the flow of fluids in the fluidic device. The vacuum pump can be used to pull a fluid in a specific direction in a channel, and the gas pump can be used to push a fluid in a specific direction in a channel. The broken open valve can be used to connect two separate regions at the control of a user, and the self-close valve can be used to automatically seal off a channel after passage of a fluid. The vacuum pumps, gas pumps, broken open valves, and self close valves can be made small in volume so that the fluidic device can be made as a small and portable device.

Abstract: A fluidic device includes a first reservoir to receive a first fluid, a second reservoir to receive a second fluid, and a main channel coupled to the first and second reservoirs through one or more branch channels. A first one-use pump generates a pressure difference to move one or both of the first and second fluids when a container in the first one-use pump is broken. A second one-use pump generates a pressure difference to move one or both of the first and second fluids when a container in the second one-use pump is broken.