Abstract: Disclosed is a method for multi-center effect compensation based on a PET/CT intelligent diagnosis system. The method includes the following steps: estimating multi-center effect parameters of a test center B relative to a training center A by implementing a nonparametric mathematical method for data of the training center A and the test center B based on a location-scale model about additive and multiplicative multi-center effect parameters, and using the parameters to compensate the data of the test center B to eliminate a multi-center effect between the test center B and the training center A. According to the present disclosure, the multi-center effect between the training center A and the test center B can be compensated, so that the compensated data of the test center B can be used in the model trained by the training center A, and the generalization ability of the model is indirectly improved.

Abstract: Disclosed is a method for multi-center effect compensation based on a PET/CT intelligent diagnosis system. The method includes the following steps: estimating multi-center effect parameters of a test center B relative to a training center A by implementing a nonparametric mathematical method for data of the training center A and the test center B based on a location-scale model about additive and multiplicative multi-center effect parameters, and using the parameters to compensate the data of the test center B to eliminate a multi-center effect between the test center B and the training center A. According to the present disclosure, the multi-center effect between the training center A and the test center B can be compensated, so that the compensated data of the test center B can be used in the model trained by the training center A, and the generalization ability of the model is indirectly improved.

Abstract: Disclosed is a three-dimensional low-dose PET reconstruction method based on deep learning. The method comprises the following steps: back projecting low-dose PET raw data to the image domain to maintain enough information from the raw data; selecting an appropriate three-dimensional deep neural network structure to fit the mapping between the back projection of the low-dose PET and a standard-dose PET image; after learning from the training samples the network parameters are fixed, realizing three-dimensional PET image reconstruction starting from low-dose PET raw data, thereby obtaining a low-dose PET reconstructed image which has a lower noise and a higher resolution compared with the traditional reconstruction algorithm and image domain noise reduction processing.

Abstract: A method for calibrating defective channels of a CT device involves in a step S10, acquiring original data collected by the CT device; in a step S20, capturing to-be-recovered areas from the original data, wherein the to-be-recovered areas contain the defective channels of the CT device; in a step S30, inputting data of the to-be-recovered areas to a neural network for training so as to generate training results; and in a step S40, using the training results to repair the to-be-recovered areas. The method eliminates effects of artifacts caused by defective channels on image reconstruction.

Abstract: A method for calibrating defective channels of a CT device involves in a step S10, acquiring original data collected by the CT device; in a step S20, capturing to-be-recovered areas from the original data, wherein the to-be-recovered areas contain the defective channels of the CT device; in a step S30, inputting data of the to-be-recovered areas to a neural network for training so as to generate training results; and in a step S40, using the training results to repair the to-be-recovered areas. The method eliminates effects of artifacts caused by defective channels on image reconstruction.