Abstract: Instructions are generated to manipulate target objects and relationships in a relational database when a source object having a one-to-many relationship of privately owned type with the target objects is manipulated. To generate instructions, mapping meta-data is used which contains information as to how object classes of the object model map to tables in the database and how relationships map to foreign keys.

Abstract: This invention provides a system and method for computer simulation of image-guided diagnostic and therapeutic procedures such as vascular catheterization, angioplasty, stent, coil and graft placement, embolotherapy and drug infusion therapy. In a particularly preferred aspect, the system is configured to resemble a cardiovascular catheterization laboratory where interventional radiology procedures are performed. A first user can interactively manipulate therapeutic catheters, guidewires and other medical devices in real-time while viewing patient-specific medical image data sets in a manner similar to that encountered in a clinical procedure.

Abstract: The invention provides a system for virtually designing a medical device conformed for use with a specific patient. Using the system, a three-dimensional geometric model of a patient-specific body cavity or lumen is reconstructed from scanned volume images such as obtained x-rays, magnetic resonance imaging (MRI), computer tomography (CT), ultrasound (US), angiography or other imaging modalities. Knowledge of the physical properties of the cavity/lumen is obtained by determining the relationship between image density and the stiffness or elasticity of tissues in the body cavity or lumen and is used to model interactions between a simulated device and a simulated body cavity or lumen.