Patents by Inventor Yaoquan Liu

Yaoquan Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and Materials for Enzymatic Synthesis of Mogroside Compounds
    Publication number: 20140308698
    Abstract: Methods and materials for enzymatic synthesis of mogroside compounds described.
    Type: Application
    Filed: November 19, 2012
    Publication date: October 16, 2014
    Inventors: Yaoquan Liu, Jung Yeop Lee, Monika Khare
  • 2-PYRIDONE ANTIMICROBIAL COMPOSITIONS
    Publication number: 20130245035
    Abstract: Described are a series of 2-pyridone compounds as a potent and selective new class of type II topoisomerase inhibitors with broad-spectrum antimicrobial activity having the general formula (I); where R1, R2, X, and Y are defined herein Such compounds can be used in methods for treating an infection caused by a gram-positive pathogen, a gram-negative pathogen, or a drug-resistant strains thereof.
    Type: Application
    Filed: September 16, 2011
    Publication date: September 19, 2013
    Applicant: EVOLVA SA
    Inventors: Patrick Roussel, Jutta Heim, Peter Schneider, Christian Bartels, Yaoquan Liu, Glen Dale, Daniel Milligan
  • LIGF-TYPE SYSTEMS FOR BIOCONVERSION OF LIGNIN-DERIVED COMPOUNDS
    Publication number: 20130143304
    Abstract: The teachings provided herein are generally directed to a method of converting lignin-derived compounds to valuable aromatic chemicals using an enzymatic, bioconversion process. The teachings provide a selection of (i) host cells that are tolerant to the toxic compounds present in lignin fractions; (ii) polypeptides that can be used as enzymes in the bioconversion of the lignin fractions to the aromatic chemical products; (iii) polynucleotides that can be used to transform the host cells to express the selection of polypeptides as enzymes in the bioconversion of the lignin fractions; and (iv) the transformants that express the enzymes.
    Type: Application
    Filed: August 29, 2011
    Publication date: June 6, 2013
    Inventors: RANJINI CHATTERJEE, KENNETH ZAHN, KENNETH MITCHELL, YAOQUAN LIU
  • LIGE-TYPE ENZYMES FOR BIOCONVERSION OF LIGNIN-DERIVED COMPOUNDS
    Publication number: 20120202257
    Abstract: The teachings provided herein are generally directed to a method of converting lignin-derived compounds to valuable aromatic chemicals using an enzymatic, bioconversion process. The teachings provide a selection of (i) host cells that are tolerant to the toxic compounds present in lignin fractions; (ii) polypeptides that can be used as enzymes in the bioconversion of the lignin fractions to the aromatic chemical products; (iii) polynucleotides that can be used to transform the host cells to express the selection of polypeptides as enzymes in the bioconversion of the lignin fractions; and (iv) the transformants that express the enzymes.
    Type: Application
    Filed: August 29, 2011
    Publication date: August 9, 2012
    Inventors: Ranjini Chatterjee, Kenneth Zahn, Kenneth Mitchell, Yaoquan Liu
  • LIGE-TYPE SYSTEMS FOR BIOCONVERSION OF LIGNIN-DERIVED COMPOUNDS
    Publication number: 20120202272
    Abstract: The teachings provided herein are generally directed to a method of converting lignin-derived compounds to valuable aromatic chemicals using an enzymatic, bioconversion process. The teachings provide a selection of (i) host cells that are tolerant to the toxic compounds present in lignin fractions; (ii) polypeptides that can be used as enzymes in the bioconversion of the lignin fractions to the aromatic chemical products; (iii) polynucleotides that can be used to transform the host cells to express the selection of polypeptides as enzymes in the bioconversion of the lignin fractions; and (iv) the transformants that express the enzymes.
    Type: Application
    Filed: August 29, 2011
    Publication date: August 9, 2012
    Inventors: Ranjini Chatterjee, Kenneth Zahn, Kenneth Mitchell, Yaoquan Liu
  • LIGE-TYPE TRANSFORMANTS FOR BIOCONVERSION OF LIGNIN-DERIVED COMPOUNDS
    Publication number: 20120202258
    Abstract: The teachings provided herein are generally directed to a method of converting lignin-derived compounds to valuable aromatic chemicals using an enzymatic, bioconversion process. The teachings provide a selection of (i) host cells that are tolerant to the toxic compounds present in lignin fractions; (ii) polypeptides that can be used as enzymes in the bioconversion of the lignin fractions to the aromatic chemical products; (iii) polynucleotides that can be used to transform the host cells to express the selection of polypeptides as enzymes in the bioconversion of the lignin fractions; and (iv) the transformants that express the enzymes.
    Type: Application
    Filed: August 29, 2011
    Publication date: August 9, 2012
    Inventors: Ranjini Chatterjee, Kenneth Zahn, Kenneth Mitchell, Yaoquan Liu
  • LIGF-TYPE TRANSFORMANTS FOR BIOCONVERSION OF LIGNIN-DERIVED COMPOUNDS
    Publication number: 20120196335
    Abstract: The teachings provided herein are generally directed to a method of converting lignin-derived compounds to valuable aromatic chemicals using an enzymatic, bioconversion process. The teachings provide a selection of (i) host cells that are tolerant to the toxic compounds present in lignin fractions; (ii) polypeptides that can be used as enzymes in the bioconversion of the lignin fractions to the aromatic chemical products; (iii) polynucleotides that can be used to transform the host cells to express the selection of polypeptides as enzymes in the bioconversion of the lignin fractions; and (iv) the transformants that express the enzymes.
    Type: Application
    Filed: August 29, 2011
    Publication date: August 2, 2012
    Inventors: RANJINI CHATTERJEE, KENNETH ZAHN, KENNETH MITCHELL, YAOQUAN LIU
  • LIGF-TYPE ENZYMES FOR BIOCONVERSION OF LIGNIN-DERIVED COMPOUNDS
    Publication number: 20120196334
    Abstract: The teachings provided herein are generally directed to a method of converting lignin-derived compounds to valuable aromatic chemicals using an enzymatic, bioconversion process. The teachings provide a selection of (i) host cells that are tolerant to the toxic compounds present in lignin fractions; (ii) polypeptides that can be used as enzymes in the bioconversion of the lignin fractions to the aromatic chemical products; (iii) polynucleotides that can be used to transform the host cells to express the selection of polypeptides as enzymes in the bioconversion of the lignin fractions; and (iv) the transformants that express the enzymes.
    Type: Application
    Filed: August 29, 2011
    Publication date: August 2, 2012
    Inventors: Ranjini Chatterjee, Kenneth Zahn, Kenneth Mitchell, Yaoquan Liu
  • LIGF-TYPE SYSTEMS FOR BIOCONVERSION OF LIGNIN-DERIVED COMPOUNDS
    Publication number: 20120196353
    Abstract: The teachings provided herein are generally directed to a method of converting lignin-derived compounds to valuable aromatic chemicals using an enzymatic, bioconversion process. The teachings provide a selection of (i) host cells that are tolerant to the toxic compounds present in lignin fractions; (ii) polypeptides that can be used as enzymes in the bioconversion of the lignin fractions to the aromatic chemical products; (iii) polynucleotides that can be used to transform the host cells to express the selection of polypeptides as enzymes in the bioconversion of the lignin fractions; and (iv) the transformants that express the enzymes.
    Type: Application
    Filed: August 29, 2011
    Publication date: August 2, 2012
    Inventors: RANJINI CHATTERJEE, KENNETH ZAHN, KENNETH MITCHELL, YAOQUAN LIU
  • Carbamate compounds
    Patent number: 7795457
    Abstract: Carbamate compounds having a structure represented by formula I (where R1, R2, R3, R4, R5 and R6 are as defined herein) are useful as anti-tumor agents.
    Type: Grant
    Filed: February 20, 2008
    Date of Patent: September 14, 2010
    Assignee: Kosan Biosciences Incorporated
    Inventors: Hong Fu, Yaoquan Liu
  • Motilide compounds
    Patent number: 7582611
    Abstract: Compounds having a structure according to formula (I) where RA, RB, RC, RD, RE, and RF are as defined herein, are useful as prokinetic agents.
    Type: Grant
    Filed: May 2, 2006
    Date of Patent: September 1, 2009
    Assignee: Pfizer Inc.
    Inventors: Yaoquan Liu, Christopher Carreras, David C. Myles, Yong Li, Simon James Shaw, Hong Fu, Yue Chen, Hao Zheng, Yandong Li, Mark A. Burlingame
  • Carbamate compounds
    Publication number: 20080214617
    Abstract: Carbamate compounds having a structure represented by formula I (where R1, R2, R3, R4, R5 and R6 are as defined herein) are useful as anti-tumor agents.
    Type: Application
    Filed: February 20, 2008
    Publication date: September 4, 2008
    Inventors: Hong Fu, Yaoquan Liu
  • N-desmethyl-N-substituted-11-deoxyerythromycin compounds
    Patent number: 7407941
    Abstract: Compounds having the structure of formula I wherein R1, R2, R3, R4, R5, and R6 are as defined herein, are prokinetic agents and can be used to treat disorders of gastric motility.
    Type: Grant
    Filed: August 24, 2004
    Date of Patent: August 5, 2008
    Assignee: Pfizer, Inc.
    Inventors: Christopher Carreras, Yaoquan Liu
  • Geldanamycin compounds and method of use
    Patent number: 7378407
    Abstract: Geldanamycin compounds having a structure according to formula I where Q1, L, L1, R5, R6, and R11 are as defined herein, are useful for treating a disease or disorder ameliorated by inhibiting the function of extracellular heat shock protein-90.
    Type: Grant
    Filed: July 6, 2007
    Date of Patent: May 27, 2008
    Assignee: Kosan Biosciences Incorporated
    Inventors: Daniel V. Santi, Zong-Qiang Tian, Yaoquan Liu, Zhan Wang
  • Geldanamycin compounds and method of use
    Publication number: 20070270396
    Abstract: Geldanamycin compounds having a structure according to formula I where Q1, L, L1, R5, R6, and R11 are as defined herein, are useful for treating a disease or disorder ameliorated by inhibiting the function of extracellular heat shock protein-90.
    Type: Application
    Filed: July 6, 2007
    Publication date: November 22, 2007
    Applicant: Kosan Biosciences Incorporated
    Inventors: Daniel Santi, Zong-Qiang Tian, Yaoquan Liu, Zhan Wang
  • Geldanamycin compounds and method of use
    Patent number: 7259156
    Abstract: Geldanamycin compounds having a structure according to formula I where Q1, L, L1, R5, R6, and R11 are as defined herein, are useful for treating a disease or disorder ameliorated by inhibiting the function of extracellular heat shock protein-90.
    Type: Grant
    Filed: May 17, 2005
    Date of Patent: August 21, 2007
    Assignee: Kosan Biosciences Incorporated
    Inventors: Daniel V. Santi, Zong-Qiang Tian, Yaoquan Liu, Zhan Wang
  • Method for demethylating the 3'-dimethylamino group of erythromycin compounds
    Publication number: 20070135362
    Abstract: A method for demethylating the 3?-dimethylamino group of erythromycin compounds.
    Type: Application
    Filed: November 1, 2006
    Publication date: June 14, 2007
    Inventor: Yaoquan Liu
  • 9-Desoxoerythromycin compounds as prokinetic agents
    Patent number: 7211568
    Abstract: 9-Desoxoerythromycin compounds of formula I wherein R1, R2, R3, R4, and R5 are as defined herein, are useful as prokinetic agents for treating disorders of gastric motility.
    Type: Grant
    Filed: December 15, 2004
    Date of Patent: May 1, 2007
    Assignee: Kosan Biosciences Incorporated
    Inventors: Yaoquan Liu, Christopher Carreras, David C. Myles
  • Motilide compounds
    Publication number: 20060270616
    Abstract: Compounds having a structure according to formula (I) where RA, RB, RC, RD, RE, and RF are as defined herein, are useful as prokinetic agents.
    Type: Application
    Filed: May 2, 2006
    Publication date: November 30, 2006
    Inventors: Yaoquan Liu, Christopher Carreras, David Myles, Yong Li, Simon Shaw, Hong Fu, Yue Chen, Hao Zheng, Yandong Li, Mark Burlingame
  • Geldanamycin compounds and method of use
    Publication number: 20050267046
    Abstract: Geldanamycin compounds having a structure according to formula I where Q1, L, L1, R5, R6, and R11 are as defined herein, are useful for treating a disease or disorder ameliorated by inhibiting the function of extracellular heat shock protein-90.
    Type: Application
    Filed: May 17, 2005
    Publication date: December 1, 2005
    Inventors: Daniel Santi, Zong-Qiang Tian, Yaoquan Liu, Zhan Wang