Abstract: The present invention relates to a thermoelectric refrigeration module, comprising a TEC refrigerating piece (8) having a top surface and a bottom surface, a radiator (16) closely contacted to the bottom surface of the TEC refrigerating piece (8), and a cold eliminator (18) including a brick body (4) having a bottom surface adhered to the top surface of the TEC refrigerating piece (8), characterized in that a thermal insulation frame structure (7) is disposed between the radiator (16) and the cold eliminator (18); the brick body of the cold eliminator and the TEC refrigerating piece are located within thermal insulation frame structure (7); the radiator and the cold eliminator are connected to the thermal insulation frame structure (7) via a connecting piece respectively; the cold eliminator has an end portion at which a plurality of cold aluminum fins are provided; a locating frame structure (1) having an inside frame, within which the end portion of the cold eliminator is located, is provided; the inside fr