Abstract: A system and method for performing quiet magnetic resonance imaging (“MRI”) are provided. An MRI system is directed to perform a pulse sequence that includes a magnetic field gradient s tapped through a plurality of different gradient component amplitude values in a manner that controls the difference between successive gradient amplitudes. In this way, force changes generated during the transition from one gradient component amplitude to the next are controlled, thereby resulting in a significant noise reduction. Additionally, the gradient amplitude values are ordered such that the transition of the gradient component amplitude in successive repetitions of the pulse sequence is controlled, thereby mitigating the generation of forces between pulse sequence repetitions.

Abstract: An apparatus and technique for measuring volumetric, 3-D bone organic matrix density is described. The techniques includes providing a first pulse sequence fragment selected to suppress at least two fluid resonance signals and providing a second pulse sequence fragment which images at least solid signals. In one embodiment, a series of RF pulses used to suppress fluid in the bone marrow spaces, particularly in cancellous bone tissue, is combined with solid state projection reconstruction magnetic resonance imaging (MRI) to provide a three-dimensional image of a bone in which the dominant signal arises substantially from solid organic bone matrix.

Abstract: An apparatus and technique for measuring volumetric, 3-D bone organic matrix density is described. The techniques includes providing a first pulse sequence fragment selected to suppress at least two fluid resonance signals and providing a second pulse sequence fragment which images at least solid signals. In one embodiment, a series of RF pulses used to suppress fluid in the bone marrow spaces, particularly in cancellous bone tissue, is combined with solid state projection reconstruction magnetic resonance imaging (MRI) to provide a three-dimensional image of a bone in which the dominant signal arises substantially from solid organic bone matrix.

Abstract: Principles of magnetic resonance are employed to generate data, such as image intensity data, reflecting the spatial distribution of one or more isotopes carried in a solid-state specimen such as bone. The spatial distribution data can be employed, e.g., to calculate bone mineral density and/or degree of mineralization.