Patents by Inventor Yaoxin LIN

Yaoxin LIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lipid compound and use thereof in delivery of nucleic acid
    Patent number: 12508225
    Abstract: Provided are an ionizable lipid compound with an adjacent cis-double bond structure, a preparation method therefor, and the use thereof in the delivery of an active therapeutic agent (e.g., a nucleic acid). The ionizable lipid compound can provide a higher encapsulation rate of active substances and a better cell or in vivo transfection rate, and is particularly suitable for preparing nanoparticles with a solid structure.
    Type: Grant
    Filed: May 23, 2022
    Date of Patent: December 30, 2025
    Assignee: BEIJING TRICISIONBIO THERAPEUTICS INC.
    Inventors: Yaoxin Lin, Chengqiang Gao, Shiyou Li, Hao Wang, Lei Wu, Qi Xin
  • LIPID COMPOUND AND USE THEREOF IN DELIVERY OF NUCLEIC ACID
    Publication number: 20240252434
    Abstract: Provided are an ionizable lipid compound with an adjacent cis-double bond structure, a preparation method therefor, and the use thereof in the delivery of an active therapeutic agent (e.g., a nucleic acid). The ionizable lipid compound can provide a higher encapsulation rate of active substances and a better cell or in vivo transfection rate, and is particularly suitable for preparing nanoparticles with a solid structure.
    Type: Application
    Filed: May 23, 2022
    Publication date: August 1, 2024
    Inventors: Yaoxin LIN, Chengqiang GAO, Shiyou LI, Hao WANG, Lei WU, Qi XIN