Patents by Inventor Yaoying HAN

Yaoying HAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for preparing nitrogen-containing heterocyclic compound and derivative thereof by enzymatic-chemical cascade method
    Patent number: 12024732
    Abstract: A method for preparing a nitrogen-containing heterocyclic compound and a derivative thereof by an enzymatic-chemical cascade method, comprising: reacting an alcohol, an amine, an alcohol dehydrogenase, a flavin molecule and a coenzyme in a solvent to obtain the nitrogen-containing heterocyclic compound and the derivative thereof; compared with the prior art, the method is a green and economical enzymatic-chemical cascade method, and is used for synthesizing nitrogen-containing heterocyclic compounds and derivatives thereof; compared with a common toxic chemical catalyst, the alcohol dehydrogenase is selected as a catalyst in the method, which has the characteristics of high substrate specificity, no pollution, high catalytic efficiency, no toxic solvents and simple post-treatment.
    Type: Grant
    Filed: August 18, 2021
    Date of Patent: July 2, 2024
    Assignee: NANJING TECH UNIVERSITY
    Inventors: Chenjie Zhu, Hanjie Ying, Zhuotao Tan, Wei Zhuang, Yaping Fu, Yaoying Han, Ming Li, Yong Chen, Dong Liu, Huanqing Niu, Pengpeng Yang
  • METHOD FOR PREPARING NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND DERIVATIVE THEREOF BY ENZYMATIC-CHEMICAL CASCADE METHOD
    Publication number: 20240026400
    Abstract: A method for preparing a nitrogen-containing heterocyclic compound and a derivative thereof by an enzymatic-chemical cascade method, comprising: reacting an alcohol, an amine, an alcohol dehydrogenase, a flavin molecule and a coenzyme in a solvent to obtain the nitrogen-containing heterocyclic compound and the derivative thereof; compared with the prior art, the method is a green and economical enzymatic-chemical cascade method, and is used for synthesizing nitrogen-containing heterocyclic compounds and derivatives thereof; compared with a common toxic chemical catalyst, the alcohol dehydrogenase is selected as a catalyst in the method, which has the characteristics of high substrate specificity, no pollution, high catalytic efficiency, no toxic solvents and simple post-treatment.
    Type: Application
    Filed: August 18, 2021
    Publication date: January 25, 2024
    Inventors: Chenjie ZHU, Hanjie YING, Zhuotao TAN, Wei ZHUANG, Yaping FU, Yaoying HAN, Ming LI, Yong CHEN, Dong LIU, Huanqing NIU, Pengpeng YANG