Abstract: A fluid flow rate measurement device includes: a manifold element including a first fluid conduit extending from a surface thereof and terminating in a first port opening at a first lateral surface thereof and a second port opening at a second lateral surface thereof, and a second fluid conduit extending from a surface thereof and terminating in a third port opening at the first lateral surface and a fourth port opening at the second lateral surface; a fluid restriction element fixed to the first lateral surface and arranged to provide a sealed fluid pathway between the first port and the third port; and—a pressure sensor assembly fixed to the second lateral surface and including a first pressure sensor in fluidic communication with the second port, and a second pressure sensor in fluidic communication with the fourth port.

Abstract: A fluid flow rate measurement device includes: a manifold element including a first fluid conduit extending from a surface thereof and terminating in a first port opening at a first lateral surface thereof and a second port opening at a second lateral surface thereof, and a second fluid conduit extending from a surface thereof and terminating in a third port opening at the first lateral surface and a fourth port opening at the second lateral surface; a fluid restriction element fixed to the first lateral surface and arranged to provide a sealed fluid pathway between the first port and the third port; and—a pressure sensor assembly fixed to the second lateral surface and including a first pressure sensor in fluidic communication with the second port, and a second pressure sensor in fluidic communication with the fourth port.

Abstract: A method for controlling pipetting operations done by a pipetting device having a system for measuring the flow rate of the liquid suctioned or dispensed and electronics to communicate with a computer. The method is based on detection of flow rate variations and the moments at which those variations occur. The method includes obtaining a curve of liquid flow rate by the pipette as a function of time, computing the first deviation of the curve, identifying and recording the maximum and minimum values of the first deviation and the moments at which the maximum and minimum values occur, comparing the maximum and minimum values and the moments at which the maximum and minimum values occur with predetermined references for the values and the moments at which they occur, and based on the result of the comparison, providing a validation or error message.

Abstract: A method for controlling pipetting operations done by a pipetting device having a system for measuring the flow rate of the liquid suctioned or dispensed and electronics to communicate with a computer. The method is based on detection of flow rate variations and the moments at which those variations occur. The method includes obtaining a curve of liquid flow rate by the pipette as a function of time, computing the first deviation of the curve, identifying and recording the maximum and minimum values of the first deviation and the moments at which the maximum and minimum values occur, comparing the maximum and minimum values and the moments at which the maximum and minimum values occur with predetermined references for the values and the moments at which they occur, and based on the result of the comparison, providing a validation or error message.