Abstract: A cerebral hemodynamics monitoring device includes a catheter having an optic fiber 20 for measurement of oxygen saturation, a first thermistor 30 positioned not more than about 25 mm from the tip of the catheter, and a second thermistor 32, located preferably at an entry to the catheter. The catheter is insertable in a vein over a guide wire using the Seldinger technique. The monitoring device also includes a computerized cerebral hemodynamics monitor that performs continuous jugular oximetry (S.sub.j O.sub.2, %), arterial pulse oximetry (S.sub.a O.sub.2, %), and measurement of jugular blood flow (JBF, ml/min/100 g tissue), preferably via retrograde thermodilution based on data collected in the catheter devices. Based on these measurements, the monitoring device performs continuous calculation of cerebral O.sub.2 extraction (CEO.sub.2, %), cerebral O.sub.2 consumption (CMRO.sub.2), cerebral blood flow (CBF), and cerebral vascular resistance (CVR).