Patents by Inventor Yaroslav I. Khadzhai

Yaroslav I. Khadzhai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4364393
    Abstract: An absorbable surgical suture material based on monocarboxycellulose having the general formula ##STR1## where: m is a degree of polymerization of the initial cellulose from 250 to 3,300;p is a molar fraction of D-glucopyranose cycles in one polymer period from 0.95 to 0.05;q is a molar fraction of cycles of d-anhydroglucuronic acid from 0.05 to 0.95;S is a molar fraction of the complex fragment of D-anhydroglucuronic acid, metal, and ligand from 0.03 to 0.55;Me is a transition metal;n is a valence of the transition metal;k is a coordination number of the transition metal .gtoreq.4;Lig is polydentate ligands;Dent is a dentation of the ligands .gtoreq.2.A method for producing said material consists in that cellulose threads are first threaded with nitrogen oxides, then for 0.5 to 2.0 hours treated with a 0.5-2.0-percent solution of a salt of a transition metal with a coordination number not less than 4 in a suitable solvent, and after this treated for 0.5 to 2.0 hours with a 1.0-2.
    Type: Grant
    Filed: April 29, 1981
    Date of Patent: December 21, 1982
    Inventors: Boris G. Yasnitsky, Galina M. Tsukanova, Valentin A. Oridoroga, Alexandr A. Shalimov, Jury A. Furmanov, Valery P. Silchenko, Sergei A. Shalimov, Yaroslav I. Khadzhai, Galina V. Obolentseva, Nikolai E. Vorobiev
  • Patent number: 4175078
    Abstract: According to the invention, the novel substances are the cardenolide and adienolide derivatives of ajmaline of the general formula ##STR1## wherein R is cardenolide or bufadienolide of the general formula ##STR2## Z is an unsaturated five-member or six-member lactone ring of the general formula ##STR3## y' is a radical --CH.sub.3, or --CHO; y" is H or OH,X is a halogen.According to the present invention, the process for producing the cardenolide or bufadienolide derivatives of ajmaline resides in that cardenolide or bufadienolide is reacted with acid halides in a medium of an organic solvent, which does not react with organic acid anhydrides, at a temperature of -10.degree. to +25.degree. C., and added to the thus-obtained halide of cardenolide or bufadienolide is ajmaline in a medium of said organic solvent, followed by isolation of the end product.
    Type: Grant
    Filed: July 14, 1978
    Date of Patent: November 20, 1979
    Assignee: Kharkovsky Naucho-Issledovatelsky Khimfo-Farmatsevtiches-Ky Institut
    Inventors: Ivan F. Makarevich, Yaroslav I. Khadzhai, Valeria V. Pavlova, Anastasia V. Nikolaeva
  • Patent number: 4159334
    Abstract: A medicinal preparation with an antiinflammatory, analgesic and antipyretic effect, comprising 2,2,2-trichloro-1-(2-thiazolyl amino)-ethanol as the active principle, which has the following formula: ##STR1## and an appropriate pharmaceutical carrier. The preparation is used for the treatment of various diseases, for example: rheumatism in the active phase, rheumatoid, infectious allergic and metabolic arthritis, spondyloses and arthroses, lumbosacral radiculitis, and others.
    Type: Grant
    Filed: October 3, 1977
    Date of Patent: June 26, 1979
    Inventors: Boris G. Yasnitsky, Yaroslav I. Khadzhai, Galina V. Obolentseva, Elena B. Dolberg, Alexandra I. Vidjukova, Tatyana V. Medvedeva, Nina A. Bugrim, Viktor P. Georgievsky