Patents by Inventor Yasamin Moazami
Yasamin Moazami has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20260200961Abstract: Provided herein is a compound of Formula (I): or a pharmaceutically acceptable salt, stereoisomer, mixture of stereoisomers, or deuterated analog thereof; a pharmaceutical composition comprising a compound of the present disclosure, together with a pharmaceutically acceptable excipient; and a method of treating cancer with the same.Type: ApplicationFiled: December 17, 2025Publication date: July 16, 2026Inventors: Jonah J. Chang, Stephen D. Holmbo, Jesse M. Jacobsen, David L. Kukla, Yasamin Moazami, Stephane Perreault, Jennifer A. Treiberg
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Publication number: 20260159501Abstract: Provided herein is a compound of Formula I: or a pharmaceutically acceptable salt, stereoisomer, mixture of stereoisomers, or deuterated analog thereof, a pharmaceutical composition comprising a compound of the present invention, together with a pharmaceutically acceptable excipient thereof, and a method of treating cancer with the same.Type: ApplicationFiled: October 1, 2025Publication date: June 11, 2026Inventors: Jayaraman Chandrasekhar, Jonah J. Chang, Kevin S. Currie, Stephen D. Holmbo, Jesse M. Jacobsen, David L. Kukla, Seung H. Lee, Yasamin Moazami, Leena B. Patel, Thomas J. Paul, Stephane Perreault, Patrick J. Salvo, Jennifer A. Treiberg, Heath A. Weaver
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Publication number: 20250361236Abstract: The present disclosure provides diacylglycerol kinase modulating compounds, and pharmaceutical compositions thereof, for treating cancer, including solid tumors, and viral infections, such as HIV or hepatitis B virus infection. The compounds can be used alone or in combination with other agents.Type: ApplicationFiled: April 25, 2024Publication date: November 27, 2025Inventors: Masaaki Sawa, Mai Arai, Ryoko Nakai, Hirokazu Matsumoto, Catherine Pugh, Eric Hu, Juan Guerrero, Jesse Jacobsen, Jonathan William Medley, Jie Xu, Latesh Lad, Leena Patel, Michael Graupe, Qingming Zhu, Stephen Holmbo, Tetsuya Kobayashi, Will Watkins, Yasamin Moazami, Suet C. Yeung, Julian A. Codelli, Heath A. Weaver
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Publication number: 20250353817Abstract: The present disclosure relates generally to compounds that inhibit IL-17A. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through inhibiting IL-17A. The disclosure further relates to the use of the compounds for therapy.Type: ApplicationFiled: April 4, 2025Publication date: November 20, 2025Inventors: James L. Bachman, Peter A. Blomgren, Julian A. Codelli, Jesse M. Jacobsen, Scott R. Miskey, Yasamin Moazami, Prasenjit K. Mukherjee, Leena B. Patel, Thomas J. Paul, Alexander W. Rand, Heath A. Weaver, Suet C. Yeung
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Patent number: 12459922Abstract: Provided herein is a compound of Formula I: or a pharmaceutically acceptable salt, stereoisomer, mixture of stereoisomers, or deuterated analog thereof, a pharmaceutical composition comprising a compound of the present invention, together with a pharmaceutically acceptable excipient thereof, and a method of treating cancer with the same.Type: GrantFiled: January 26, 2023Date of Patent: November 4, 2025Assignee: Gilead Sciences, Inc.Inventors: Jayaraman Chandrasekhar, Jonah J. Chang, Kevin S. Currie, Stephen D. Holmbo, Jesse M. Jacobsen, David L Kukla, Seung H. Lee, Yasamin Moazami, Leena B. Patel, Thomas J. Paul, Stephane Perreault, Patrick J. Salvo, Jennifer A. Treiberg, Heath A. Weaver
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Publication number: 20250163030Abstract: Provided herein is a compound of Formula (I) wherein the various substituents are described herein.Type: ApplicationFiled: October 24, 2024Publication date: May 22, 2025Inventors: Gayatri Balan, Jayaraman Chandrasekhar, Jonah J. Chang, Kevin S. Currie, Stephen D. Holmbo, Jesse M. Jacobsen, Jeffrey E. Kropf, Seung H. Lee, Yasamin Moazami, Leena B. Patel, Thomas J. Paul, Stephane Perreault, Patrick J. Salvo, Jennifer A. Treiberg, Heath A. Weaver
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Publication number: 20250100998Abstract: Provided herein is a compound of Formula I: or a pharmaceutically acceptable salt, stereoisomer, mixture of stereoisomers, or deuterated analog thereof, a pharmaceutical composition comprising a compound of the present invention, together with a pharmaceutically acceptable excipient thereof, and a method of treating cancer with the same.Type: ApplicationFiled: July 26, 2024Publication date: March 27, 2025Inventors: Jayaraman Chandrasekhar, Jonah J. Chang, Kevin S. Currie, Stephen D. Holmbo, Jesse M. Jacobsen, David L. Kukla, Seung H. Lee, Yasamin Moazami, Leena B. Patel, Thomas J. Paul, Stephane Perreault, Patrick J. Salvo, Jennifer A. Treiberg, Heath A. Weaver
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Publication number: 20250066328Abstract: Provided herein is a compound of Formula (I): or a pharmaceutically acceptable salt, stereoisomer, mixture of stereoisomers, or deuterated analog thereof, a pharmaceutical composition comprising a compound of the present disclosure, together with a pharmaceutically acceptable excipient thereof, and a method of treating cancer with the same.Type: ApplicationFiled: July 25, 2024Publication date: February 27, 2025Inventors: Jonah J. Chang, Jayaraman Chandrasekhar, Kevin S. Currie, Stephen D. Holmbo, Jesse M. Jacobsen, David L. Kukla, Seung H. Lee, Yasamin Moazami, Leena B. Patel, Thomas J. Paul, Stephane Perreault, Patrick J. Salvo, Jennifer A. Treiberg, Heath A. Weaver
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Publication number: 20250049780Abstract: The present disclosure relates generally to certain compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions provided herein may be used for the treatment or prevention of an autoimmune disease and/or inflammatory condition, including systemic lupus erythematosus and cutaneous lupus erythematosus.Type: ApplicationFiled: July 12, 2024Publication date: February 13, 2025Inventors: Stephen E. Ammann, Eda Y. Canales, Weng K. Chang, Henok H. Kinfe, Scott E. Lazerwith, Michael L. Mitchell, Yasamin Moazami, Scott D. Schroeder, Daniel G. Shore
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Publication number: 20250032473Abstract: The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.Type: ApplicationFiled: June 11, 2024Publication date: January 30, 2025Inventors: Peter A. Blomgren, Taryn Campbell, Jayaraman Chandrasekhar, Christopher T. Clark, Julian A. Codelli, Kevin S. Currie, Jeffrey E. Kropf, Yasamin Moazami, Nicole Nava, Leena Patel, Stephane Perreault, Jason K. Perry, Kassandra F. Sedillo, Natalie Seeger, Kirk L. Stevens, Jennifer Anne Treiberg, Suet C. Yeung, Zhongdong Zhao
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Publication number: 20240400568Abstract: The present disclosure provides diacylglycerol kinase modulating compounds, and pharmaceutical compositions thereof, for treating cancer, including solid tumors, and viral infections, such as HIV or hepatitis B virus infection. The compounds can be used alone or in combination with other agents.Type: ApplicationFiled: April 25, 2024Publication date: December 5, 2024Inventors: Masaaki Sawa, Mai Arai, Ryoko Nakai, Hirokazu Matsumoto, Catherine Pugh, Eric Hu, Juan Guerrero, Jesse Jacobsen, Jonathan William Medley, Jie Xu, Latesh Lad, Leena Patel, Michael Graupe, Qingming Zhu, Stephen Holmbo, Tetsuya Kobayashi, Will Watkins, Yasamin Moazami, Suet C. Yeung, Julian A. Codelli, Heath A. Weaver
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Patent number: 12070455Abstract: The present disclosure relates generally to certain compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions provided herein may be used for the treatment or prevention of an autoimmune disease and/or inflammatory condition, including systemic lupus erythematosus and cutaneous lupus erythematosus.Type: GrantFiled: September 8, 2022Date of Patent: August 27, 2024Assignee: Gilead Sciences, Inc.Inventors: Stephen E. Ammann, Eda Y. Canales, Weng K. Chang, Henok H. Kinfe, Scott E. Lazerwith, Michael L. Mitchell, Yasamin Moazami, Scott D. Schroeder, Daniel G. Shore
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Patent number: 12053462Abstract: The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.Type: GrantFiled: July 19, 2021Date of Patent: August 6, 2024Assignee: Gilead Sciences, Inc.Inventors: Peter A. Blomgren, Taryn Campbell, Jayaraman Chandrasekhar, Christopher T. Clark, Julian A. Codelli, Kevin S. Currie, Jeffrey E. Kropf, Yasamin Moazami, Nicole Nava, Leena Patel, Stephane Perreault, Jason K. Perry, Kassandra F. Sedillo, Natalie Seeger, Kirk L. Stevens, Jennifer Anne Treiberg, Suet C. Yeung, Zhongdong Zhao
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Publication number: 20240182476Abstract: The present disclosure provides diacylglycerol kinase modulating compounds, and pharmaceutical compositions thereof, for treating cancer, including solid tumors, and viral infections, such as HIV or hepatitis B virus infection. The compounds can be used alone or in combination with other agents.Type: ApplicationFiled: August 16, 2023Publication date: June 6, 2024Inventors: Masaaki Sawa, Mai Arai, Ryoko Nakai, Hirokazu Matsumoto, Catherine Pugh, Eric Hu, Juan Guerrero, Jesse Jacobsen, Jonathan William Medley, Jie Xu, Latesh Lad, Leena Patel, Michael Graupe, Qingming Zhu, Stephen Holmbo, Tetsuya Kobayashi, Will Watkins, Yasamin Moazami, Suet C. Yeung, Julian A. Codelli, Heath A. Weaver
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Patent number: 11976072Abstract: The present disclosure provides diacylglycerol kinase modulating compounds, and pharmaceutical compositions thereof, for treating cancer, including solid tumors, and viral infections, such as HIV or hepatitis B virus infection. The compounds can be used alone or in combination with other agents.Type: GrantFiled: June 21, 2022Date of Patent: May 7, 2024Assignee: Gilead Sciences, Inc.Inventors: Julian A. Codelli, Michael Graupe, Juan A. Guerrero, Stephen D. Holmbo, Tetsuya Kobayashi, Yasamin Moazami, Leena B. Patel, Heath A. Weaver, Jie Xu, Suet C. Yeung, QingMing Zhu
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Patent number: 11926628Abstract: The present disclosure provides diacylglycerol kinase modulating compounds, and pharmaceutical compositions thereof, for treating cancer, including solid tumors, and viral infections, such as HIV or hepatitis B virus infection. The compounds can be used alone or in combination with other agents.Type: GrantFiled: June 21, 2022Date of Patent: March 12, 2024Assignee: Gilead Sciences, Inc.Inventors: Julian A. Codelli, Michael Graupe, Juan A. Guerrero, Jesse M. Jacobsen, Tetsuya Kobayashi, Jonathan William Medley, Yasamin Moazami, Leena B. Patel, Jie Xu, Suet C. Yeung
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Patent number: 11845723Abstract: The present disclosure provides diacylglycerol kinase modulating compounds, and pharmaceutical compositions thereof, for treating cancer, including solid tumors, and viral infections, such as HIV or hepatitis B virus infection. The compounds can be used alone or in combination with other agents.Type: GrantFiled: December 18, 2020Date of Patent: December 19, 2023Assignee: Gilead Sciences, Inc.Inventors: Masaaki Sawa, Mai Arai, Ryoko Nakai, Hirokazu Matsumoto, Catherine Pugh, Eric Hu, Juan Guerrero, Jesse Jacobsen, Jonathan William Medley, Jie Xu, Latesh Lad, Leena Patel, Michael Graupe, Qingming Zhu, Stephen Holmbo, Tetsuya Kobayashi, Will Watkins, Yasamin Moazami, Suet C. Yeung, Julian A. Codelli, Heath A. Weaver
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Publication number: 20230365594Abstract: The present disclosure relates generally to certain compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions provided herein may be used for the treatment or prevention of an autoimmune disease and/or inflammatory condition, including systemic lupus erythematosus and cutaneous lupus erythematosus.Type: ApplicationFiled: March 8, 2023Publication date: November 16, 2023Inventors: Stephen E. Ammann, Eda Y. Canales, Weng K. Chang, Henok H. Kinfe, Scott E. Lazerwith, Michael L. Mitchell, Yasamin Moazami, Scott D. Schroeder, Daniel G. Shore, Christopher J. Swank
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Publication number: 20230365529Abstract: Provided herein is a compound of Formula I: or a pharmaceutically acceptable salt, stereoisomer, mixture of stereoisomers, or deuterated analog thereof, a pharmaceutical composition comprising a compound of the present invention, together with a pharmaceutically acceptable excipient thereof, and a method of treating cancer with the same.Type: ApplicationFiled: January 26, 2023Publication date: November 16, 2023Inventors: Jayaraman Chandrasekhar, Jonah J. Chang, Kevin S. Currie, Stephen D. Holmbo, Jesse M. Jacobsen, David L. Kukla, Seung H. Lee, Yasamin Moazami, Leena B. Patel, Thomas J. Paul, Stephane Perreault, Patrick J. Salvo, Jennifer A. Treiberg, Heath A. Weaver
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Publication number: 20230270734Abstract: The present disclosure relates generally to certain compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions provided herein may be used for the treatment or prevention of an autoimmune disease and/or inflammatory condition, including systemic lupus erythematosus and cutaneous lupus erythematosus.Type: ApplicationFiled: September 8, 2022Publication date: August 31, 2023Inventors: Stephen E. Ammann, Eda Y. Canales, Weng K. Chang, Henok H. Kinfe, Scott E. Lazerwith, Michael L. Mitchell, Yasamin Moazami, Scott D. Schroeder, Daniel G. Shore