Patents by Inventor Yash Kapoor

Yash Kapoor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STABLE FORMULATIONS OF CYCLIC DINUCLEOTIDE STING AGONIST COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20220175811
    Abstract: The invention relates to stable formulations of cyclic dinucleotide STING agonist compounds or pharmaceutically acceptable salts thereof. The invention further provides methods for treating various cancers with stable formulations of the invention. In some embodiments of the methods of the invention, the formulations are administered to a subject by intratumoral or subcutaneous administration.
    Type: Application
    Filed: March 24, 2020
    Publication date: June 9, 2022
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Margaret Brunell, Erin N. Guidry, Yash Kapoor, Eric A. Kemp, Ellen C. Minnihan, Sachin Mittal, Elizabeth Pierson, Mikhail Reibarkh, Tammy W. Shen, Erika R. Walsh, Paul L. Walsh
  • Azetidinium-containing copolymers and uses thereof
    Patent number: 10611923
    Abstract: The invention is related to azetidinium-containing copolymers and vinylic monomers and their uses in formation of non-silicone hydrogel coatings on silicone hydrogel contact lenses.
    Type: Grant
    Filed: August 8, 2018
    Date of Patent: April 7, 2020
    Assignee: Alcon Inc.
    Inventors: Troy Vernon Holland, Frank Chang, Yongxing Qiu, John Dallas Pruitt, Chung-Yuan Chiang, Venkat Shankar, Robert Scott, Yash Kapoor
  • Method for producing contact lenses with durable lubricious coatings thereon
    Patent number: 10266445
    Abstract: The invention is related to a method for producing silicone hydrogel contact lenses with having a stable coating thereon. A method of the invention comprises a water-based coating process (step) for forming a relatively-stable base coating of a homo- or copolymer of acrylic acid or C1-C3 alkylacrylic acid onto a silicone hydrogel contact lens made from a lens formulation comprising from about 35% to about 60% by weight of N-vinylpyrrolidone.
    Type: Grant
    Filed: May 4, 2016
    Date of Patent: April 23, 2019
    Assignee: Novartis AG
    Inventors: Bradley Quinter, Troy Vernon Holland, Yash Kapoor
  • AZETIDINIUM-CONTAINING COPOLYMERS AND USES THEREOF
    Publication number: 20180346753
    Abstract: The invention is related to azetidinium-containing copolymers and vinylic monomers and their uses in formation of non-silicone hydrogel coatings on silicone hydrogel contact lenses.
    Type: Application
    Filed: August 8, 2018
    Publication date: December 6, 2018
    Inventors: Troy Vernon Holland, Frank Chang, Yongxing Qiu, John Dallas Pruitt, Chung-Yuan Chiang, Venkat Shankar, Robert Scott, Yash Kapoor
  • Azetidinium-containing copolymers and uses thereof
    Patent number: 10100219
    Abstract: The invention is related to azetidinium-containing copolymers and vinylic monomers and their uses in formation of non-silicone hydrogel coatings on silicone hydrogel contact lenses.
    Type: Grant
    Filed: July 21, 2016
    Date of Patent: October 16, 2018
    Assignee: Novartis AG
    Inventors: Troy Vernon Holland, Frank Chang, Yongxing Qiu, John Dallas Pruitt, Chung-Yuan Chiang, Venkat Shankar, Robert Scott, Yash Kapoor
  • AZETIDINIUM-CONTAINING COPOLYMERS AND USES THEREOF
    Publication number: 20160326395
    Abstract: The invention is related to azetidinium-containing copolymers and vinylic monomers and their uses in formation of non-silicone hydrogel coatings on silicone hydrogel contact lenses.
    Type: Application
    Filed: July 21, 2016
    Publication date: November 10, 2016
    Inventors: Troy Vernon Holland, Frank Chang, Yongxing Qiu, John Dallas Pruitt, Chung-Yuan Chiang, Venkat Shankar, Robert Scott, Yash Kapoor
  • METHOD FOR PRODUCING CONTACT LENSES WITH DURABLE LUBRICIOUS COATINGS THEREON
    Publication number: 20160326046
    Abstract: The invention is related to a method for producing silicone hydrogel contact lenses with having a stable coating thereon. A method of the invention comprises a water-based coating process (step) for forming a relatively-stable base coating of a homo- or copolymer of acrylic acid or C1-C3 alkylacrylic acid onto a silicone hydrogel contact lens made from a lens formulation comprising from about 35% to about 60% by weight of N-vinylpyrrolidone.
    Type: Application
    Filed: May 4, 2016
    Publication date: November 10, 2016
    Inventors: Bradley Quinter, Troy Vernon Holland, Yash Kapoor
  • Azetidinium-containing copolymers and uses thereof
    Patent number: 9422447
    Abstract: The invention is related to azetidinium-containing copolymers and vinylic monomers and their uses in formation of non-silicone hydrogel coatings on silicone hydrogel contact lenses.
    Type: Grant
    Filed: June 10, 2013
    Date of Patent: August 23, 2016
    Assignee: Novartis AG
    Inventors: Troy Vernon Holland, Frank Chang, Yongxing Qiu, John Dallas Pruitt, Chung-Yuan Chiang, Manivakkam J. Shankernarayanan, Robert Scott, Yash Kapoor
  • AZETIDINIUM-CONTAINING COPOLYMERS AND USES THEREOF
    Publication number: 20130337160
    Abstract: The invention is related to azetidinium-containing copolymers and vinylic monomers and their uses in formation of non-silicone hydrogel coatings on silicone hydrogel contact lenses.
    Type: Application
    Filed: June 10, 2013
    Publication date: December 19, 2013
    Inventors: Troy Vernon Holland, Frank Chang, Yongxing Qiu, John Dallas Pruitt, Chung-Yuan Chiang, Manivakkam J. Shankernarayanan, Robert Scott, Yash Kapoor
  • Contact lens based bioactive agent delivery system
    Patent number: 8075909
    Abstract: A bioactive agent delivery system comprising an optically transparent contact lens having dispersed therein (1) an ophthalmically bioactive agent capable of diffusion through the contact lens and into the post-lens tear film when placed on the eye and (2) associated with the bioactive agent, an ophthalmically compatible polymeric surfactant in an amount sufficient to slow the rate of migration of the bioactive agent through the contact lens.
    Type: Grant
    Filed: September 4, 2007
    Date of Patent: December 13, 2011
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: Anuj Chauhan, Yash Kapoor
  • Dispersions of microemulsions in hydrogels for drug delivery
    Patent number: 8071121
    Abstract: An ophthalmically bioactive agent delivery system comprising a contact lens having dispersed therein as an oil-in-water microemulsion, an ophthalmically bioactive agent encapsulated in the oil phase, the oil phase comprising a material from which the agent VAN diffuse into and migrate through the contact lens into the post-lens tear film when the contact lens is placed on the eye and wherein the microemulsion is stabilized by the presence of a surfactant with sufficient packing at the oil-water interface to attenuate the rate of diffusion into and migration of agent through the contact lens.
    Type: Grant
    Filed: September 4, 2007
    Date of Patent: December 6, 2011
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: Anuj Chauhan, Derya Gulsen Onbilger, Yash Kapoor, Chi-Chung Li