Abstract: Ingestible event marker systems that include an ingestible event marker (i.e., an IEM) and a personal signal receiver are provided. Embodiments of the IEM include an identifier, which may or may not be present in a physiologically acceptable carrier. The identifier is characterized by being activated upon contact with a target internal physiological site of a body, such as digestive tract internal target site. The personal signal receiver is configured to be associated with a physiological location, e.g., inside of or on the body, and to receive a signal the IEM. During use, the IEM broadcasts a signal which is received by the personal signal receiver.

Abstract: A method comprising receiving physiologic information at a social-networking system from a body-associated personal communicator is disclosed. A social-networking system configured to receive physiological information from a body-associated personal communicator and a body-associated personal communicator configured to receive physiologic information and communicate the physiologic information to a social-networking system also are disclosed.

Abstract: A system including a sensor, a mobile device, and a computer system is disclosed. The sensor is configured to detect physiologic data from the body of the patient. The mobile device includes a patient data input device. The computer system, communicatively coupled to the mobile device, includes a patient record indicating: patient data comprising a plurality of patient activities, and detected physiological data received from the sensor via the mobile device. The computer system is configured to identify an unhealthy physiological data value from the detected physiological data of the patient record, correlate the unhealthy physiological data value to a patient activity of the patient data, select a therapeutic recommendation to address the unhealthy physiological data value, and transmit the selected therapeutic recommendation to the patient, via the mobile device, at a future time associated with the patient activity correlated to the unhealthy physiological data value.

Abstract: A method comprising receiving physiologic information at a social-networking system from a body-associated personal communicator is disclosed. A social-networking system configured to receive physiological information from a body-associated personal communicator and a body-associated personal communicator configured to receive physiologic information and communicate the physiologic information to a social-networking system also are disclosed.

Abstract: Methods, devices and systems for acquiring information useful to support a patient in implementing and adhering to a medically prescribed therapy plan are provided. The therapy may incorporate biofeedback methods and/or personalized therapy aspects. A method includes steps of receiving, by a receiving device, biometric information associated with an ingestible event marker; analyzing, by a computing device having a microprocessor configured to perform a biometric information analysis, the biometric information; and determining a therapeutic recommendation at least partly on the basis of the analysis and/or integrating biofeedback techniques into patient therapy or activity. A system includes a biometric information module to receive biometric information associated with an ingestible event marker; an analysis module to analyze the biometric information; and a determination module to optionally determine and communicate a therapeutic recommendation at least partly on the basis of the analysis.

Abstract: The disclosed system includes an ingestible event marker device configured to collect Ingestible Event Marker (IEM) data from a body of an individual and transmit a signal including the IEM data, wherein the IEM data include information associated with an ingestion event, a receiver adapted to be associated with the body of the individual and configured to receive the signal including the IEM data via the body of the individual, a hub to receive the IEM data from the receiver, and at least one IEM data system to receive the IEM data from the hub. The at least one IEM data system analyzes the IEM data and generates at least one metric based on the IEM data. The at least one IEM data system may further generate predictive information based on the at least one metric, wherein the predictive information is related to prediction of a state of the individual.

Abstract: The ingestible event marker data framework provides a uniform, comprehensive framework to enable various functions and utilities related to ingestible event marker data (IEM data). Included are a receiver adapted to be associated with a body of an individual, the receiver configured to receive IEM data; a hub to receive the IEM data; and at least one IEM data system to receive the data from the hub. Among other information, behavioral data and predictive inferences may be provided.

Abstract: The system of the present invention includes an implantable device that can detect high and low frequency current signature. The implantable device can communicate with a communication device that includes a conductive element, an electronic component, and a partial power source in the form of dissimilar materials. Upon contact with a conducting fluid, the communication device is activated.

Abstract: Systems, methods, and apparatuses are presented for resolving any interference, noise, and/or collisions caused by two or more ingestible event markers (IEMs) transmitting simultaneously or concurrently. Methods include techniques from the perspective of the IEM for randomly varying signal transmission characteristics in order to avoid collisions with other concurrently transmitting IEMs. Methods also include techniques from the perspective of a receiver for receiving multiple transmission signals from multiple IEMs and for resolving any interference or signal collisions.

Abstract: A body associated device comprises a housing, an adhesive layer configured to be applied to a body of a living subject, and at least one standoff located between the housing and the adhesive layer. An electronic module may be located within the housing of the body associated device. A personal communication system comprises a body associated device including an electronic module and further comprises a feedback portion coupled to the housing and to the electronic module. The feedback portion is configured to communicate information between the living subject and the body associated device. An external local node is operative to provide at least one of transmit communications to and receive communications from the body associated device.

Abstract: A computer-implemented method is disclosed. The computer-implemented method comprises receiving, by a computer system, ingestible event marker (IEM) system information from a receiver worn by a subject, the IEM system information comprising information associated with ingestion of medication by the subject, wherein the receiver is configured to communicate with the computer system; receiving, by the computer system, contextual information associated with the subject; and calculating, by the computer system, a composite risk score based on the IEM system information and the contextual information associated with the subject.

Abstract: A method of managing adherence to a regimen in a subscription based computer implemented healthcare information environment. The method includes receiving at a mobile device information from a receiver that a dose was ingested by a living subject. The mobile device comprises a processor, a memory and a display coupled to the processor. The method provides wirelessly communicating the information over a wireless network to a backend computer processing system and receiving from the computer at the backend processing system a personal information stream characterizing behavior of the living subject based on the received information over a predetermined period. An apparatus includes an adherence package including a foldable sheet, at least one of blister pack coupled to the foldable sheet, at least one ingestible device associated with a dose, and a perforation provided on the foldable sheet to enable removal of the at the least one blister pack.

Abstract: Receivers, which may be external or implantable, are provided. Aspects of receivers of the invention include the presence of one or more of: a high power-low power module; an intermediary module; a power supply module configured to activate and deactivate one or more power supplies to a high power processing block; a serial peripheral interface bus connecting master and slave blocks; and a multi-purpose connector. Receivers of the invention may be configured to receive a conductively transmitted signal. Also provided are systems that include the receivers, as well as methods of using the same. Additionally systems and methods are disclosed for using a receiver for coordinating with dosage delivery systems.

Abstract: Methods are provided for associating a specific one of two or more distinct fluid transfer ports of a patient with a given fluid transfer event of fluid from a parenteral fluid delivery device. Aspects of the methods include establishing a fluid transfer connection between the parenteral fluid delivery device and the patient via one of the two or more distinct fluid transfer ports and transmitting a fluid transfer signal between the parenteral fluid delivery device and a patient associated identifier using the patient's body as a signal conduction medium. Association may result in identification of the fluid transfer port that will be, is being or has been employed for the given fluid transfer event. Also provided are systems for practicing methods of the invention.

Abstract: The subject matter disclosed herein provides a response to a dose of a substance and/or controls the administration of the dose. In one aspect, there is provided a system. The system may include a processor and at least one memory configured to provide a response determinator. The response determinator may receive therapeutic and wellness data. Moreover, the response determinator may determine a response based on the received therapeutic and wellness data. The response may represent a reaction to a substance integrated with an ingestible event marker. The determined response may be provided to, for example, a therapy controller. Related systems, methods, and articles of manufacture are also described.

Abstract: A method comprising receiving physiologic information at a social-networking system from a body-associated personal communicator is disclosed. A social-networking system configured to receive physiological information from a body-associated personal communicator and a body-associated personal communicator configured to receive physiologic information and communicate the physiologic information to a social-networking system also are disclosed.

Abstract: The system of the present invention includes an implantable device that can detect high and low frequency current signature. The implantable device can communicate with a communication device that includes a conductive element, an electronic component, and a partial power source in the form of dissimilar materials. Upon contact with a conducting fluid, the communication device is activated.

Abstract: Ingestible event marker systems that include an ingestible event marker (i.e., an IEM) and a personal signal receiver are provided. Embodiments of the IEM include an identifier, which may or may not be present in a physiologically acceptable carrier. The identifier is characterized by being activated upon contact with a target internal physiological site of a body, such as digestive tract internal target site. The personal signal receiver is configured to be associated with a physiological location, e.g., inside of or on the body, and to receive a signal the IEM. During use, the IEM broadcasts a signal which is received by the personal signal receiver.

Abstract: Ingestible event marker systems that include an ingestible event marker (i.e., an IEM) and a personal signal receiver are provided. Embodiments of the IEM include an identifier, which may or may not be present in a physiologically acceptable carrier. The identifier is characterized by being activated upon contact with a target internal physiological site of a body, such as digestive tract internal target site. The personal signal receiver is configured to be associated with a physiological location, e.g., inside of or on the body, and to receive a signal the IEM. During use, the IEM broadcasts a signal which is received by the personal signal receiver.

Abstract: Receivers, which may be external or implantable, are provided. Aspects of receivers of the invention include the presence of one or more of: a high power-low power module; an intermediary module; a power supply module configured to activate and deactivate one or more power supplies to a high power processing block; a serial peripheral interface bus connecting master and slave blocks; and a multi-purpose connector. Receivers of the invention may be configured to receive a conductively transmitted signal. Also provided are systems that include the receivers, as well as methods of using the same. Additionally systems and methods are disclosed for using a receiver for coordinating with dosage delivery systems.