Patents by Inventor Yashwant M. Deo

Yashwant M. Deo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HUMAN CTLA-4 ANTIBODIES AND THEIR USES
    Publication number: 20190119384
    Abstract: The presently subject matter provides novel human sequence antibodies against human CTLA-4 and methods of treating human diseases, infections and other conditions using these antibodies.
    Type: Application
    Filed: December 26, 2018
    Publication date: April 25, 2019
    Inventors: Alan J. Korman, Edward L. Halk, Nils Lonberg, Yashwant M. Deo, Tibor P. Keler
  • HUMAN CTLA-4 ANTIBODIES AND THEIR USES
    Publication number: 20160257753
    Abstract: The presently subject matter provides novel human sequence antibodies against human CTLA-4 and methods of treating human diseases, infections and other conditions using these antibodies.
    Type: Application
    Filed: May 24, 2016
    Publication date: September 8, 2016
    Applicant: E.R. Squibb & Sons, L.L.C.
    Inventors: Alan J. Korman, Edward L. Halk, Nils Lonberg, Yashwant M. Deo, Tibor P. Keler
  • MOLECULAR CONJUGATES COMPRISING HUMAN MONOCLONAL ANTIBODIES TO DENDRITIC CELLS
    Publication number: 20160024192
    Abstract: Isolated human monoclonal antibodies and antigen-binding portions thereof which specifically bind to dendritic cells are disclosed. Also disclosed are bispecifics, immunotoxins and antigen conjugates which include the antibodies or antibody portions. The human antibodies can be produced in a non-human transgenic animal, e.g., a transgenic mouse, capable of producing multiple isotypes of human monoclonal antibodies by undergoing V-D-J recombination and isotype switching. Also disclosed are pharmaceutical compositions comprising the human antibodies, non-human transgenic animals and hybridomas which produce the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.
    Type: Application
    Filed: June 25, 2015
    Publication date: January 28, 2016
    Inventors: Yashwant M. DEO, Tibor KELER, John TREML, Michael ENDRES
  • Monoclonal antibodies to dendritic cells
    Patent number: 9095626
    Abstract: Isolated human monoclonal antibodies and antigen-binding portions thereof which specifically bind to dendritic cells are disclosed. Also disclosed are bispecifics, immunotoxins and antigen conjugates which include the antibodies or antibody portions. The human antibodies can be produced in a non-human transgenic animal, e.g., a transgenic mouse, capable of producing multiple isotypes of human monoclonal antibodies by undergoing V-D-J recombination and isotype switching. Also disclosed are pharmaceutical compositions comprising the human antibodies, non-human transgenic animals and hybridomas which produce the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.
    Type: Grant
    Filed: February 15, 2012
    Date of Patent: August 4, 2015
    Assignee: CELLDEX THERAPEUTICS, INC.
    Inventors: Yashwant M. Deo, Tibor Keler, John Treml, Michael Endres
  • HUMAN CTLA-4 ANTIBODIES AND THEIR USES
    Publication number: 20140234331
    Abstract: The present invention provides novel human sequence antibodies against human CTLA-4 and methods of treating human diseases, infections and other conditions using these antibodies.
    Type: Application
    Filed: April 28, 2014
    Publication date: August 21, 2014
    Applicant: Medarex, L.L.C.
    Inventors: Alan J. Korman, Edward L. Halk, Nils Lonberg, Yashwant M. Deo, Tibor P. Keler
  • Human CTLA-4 antibodies and their uses
    Patent number: 8784815
    Abstract: The present invention provides novel human sequence antibodies against human CTLA-4 and methods of treating human diseases, infections and other conditions using these antibodies.
    Type: Grant
    Filed: November 1, 2012
    Date of Patent: July 22, 2014
    Assignee: Medarex, L.L.C.
    Inventors: Alan J. Korman, Edward L. Halk, Nils Lonberg, Yashwant M. Deo, Tibor P. Keler
  • Human CTLA-4 antibodies and their uses
    Patent number: 8318916
    Abstract: The present invention provides novel human sequence antibodies against human CTLA-4 and methods of treating human diseases, infections and other conditions using these antibodies.
    Type: Grant
    Filed: August 4, 2011
    Date of Patent: November 27, 2012
    Assignee: Medarex, Inc.
    Inventors: Alan J. Korman, Edward L. Halk, Nils Lonberg, Yashwant M. Deo, Tibor P. Keler
  • Cell lines and methods for producing proteins
    Patent number: 8222032
    Abstract: The methods of the present invention involve the manipulation and/or propagation of oviduct tumor cells derived from either wild-type or transgenic avians.
    Type: Grant
    Filed: June 5, 2009
    Date of Patent: July 17, 2012
    Assignee: Synageva BioPharma Corp.
    Inventors: Stephen H. Parker, Yashwant M. Deo
  • MOLECULAR CONJUGATES COMPRISING HUMAN MONOCLONAL ANTIBODIES TO DENDRITIC CELLS
    Publication number: 20120148596
    Abstract: Isolated human monoclonal antibodies and antigen-binding portions thereof which specifically bind to dendritic cells are disclosed. Also disclosed are bispecifics, immunotoxins and antigen conjugates which include the antibodies or antibody portions. The human antibodies can be produced in a non-human transgenic animal, e.g., a transgenic mouse, capable of producing multiple isotypes of human monoclonal antibodies by undergoing V-D-J recombination and isotype switching. Also disclosed are pharmaceutical compositions comprising the human antibodies, non-human transgenic animals and hybridomas which produce the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.
    Type: Application
    Filed: February 15, 2012
    Publication date: June 14, 2012
    Applicant: CELLDEX RESEARCH CORPORATION
    Inventors: Yashwant M. DEO, Tibor KELER, John TREML, Michael ENDRES
  • Methods of using molecular conjugates comprising monoclonal antibodies to dendritic cells
    Patent number: 8142790
    Abstract: The present invention provides novel methods for targeting an antigen to a dendritic cell using an antibody linked to the antigen. The present invention further provides methods of inducing or enhancing an immune response and methods of immunization using an antibody linked to the antigen.
    Type: Grant
    Filed: November 26, 2008
    Date of Patent: March 27, 2012
    Assignee: Celldex Research Corporation
    Inventors: Yashwant M. Deo, Tibor Keler, John Treml, Michael Endres
  • METHODS OF USING MOLECULAR CONJUGATES COMPRISING MONOCLONAL ANTIBODIES TO DENDRITIC CELLS
    Publication number: 20120039869
    Abstract: The present invention provides novel methods for targeting an antigen to a dendritic cell using an antibody linked to the antigen. The present invention further provides methods of inducing or enhancing an immune response and methods of immunization using an antibody linked to the antigen.
    Type: Application
    Filed: November 26, 2008
    Publication date: February 16, 2012
    Applicant: CELLDEX RESEARCH CORPORATION
    Inventors: Yashwant M. DEO, Tibor KELER, John TREML, Michael ENDRES
  • Human monoclonal antibodies against CD30
    Patent number: 8088377
    Abstract: Isolated human monoclonal antibodies which bind to CD30 (e.g., human CD30) are disclosed. The human antibodies can be produced in a non-human transgenic animal, e.g., a transgenic mouse, capable of producing multiple isotypes of human monoclonal antibodies by undergoing V-D-J recombination and isotype switching. Also disclosed are derivatives of the human antibodies (e.g., bispecific antibodies and immunoconjugates), pharmaceutical compositions comprising the human antibodies, non-human transgenic animals and hybridomas which produce the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.
    Type: Grant
    Filed: April 4, 2008
    Date of Patent: January 3, 2012
    Assignee: Medarex, Inc.
    Inventors: Tibor Keler, Robert Graziano, John Treml, Yashwant M. Deo
  • Human CTLA-4 Antibodies And Their Uses
    Publication number: 20110296546
    Abstract: The present invention provides novel human sequence antibodies against human CTLA-4 and methods of treating human diseases, infections and other conditions using these antibodies.
    Type: Application
    Filed: August 4, 2011
    Publication date: December 1, 2011
    Inventors: Alan J. Korman, Edward L. Halk, Nils Lonberg, Yashwant M. Deo, Tibor P. Keler
  • Human CTLA-4 antibodies and their uses
    Patent number: 8017114
    Abstract: The present invention provides novel human sequence antibodies against human CTLA-4 and methods of treating human diseases, infections and other conditions using these antibodies.
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: September 13, 2011
    Assignee: Medarex, Inc.
    Inventors: Alan J. Korman, Edward L. Halk, Nils Lonberg, Yashwant M. Deo, Tibor P. Keler
  • Human monoclonal antibodies against CD30
    Publication number: 20100322920
    Abstract: Isolated human monoclonal antibodies which bind to CD30 (e.g., human CD30) are disclosed. The human antibodies can be produced in a non-human transgenic animal, e.g., a transgenic mouse, capable of producing multiple isotypes of human monoclonal antibodies by undergoing V-D-J recombination and isotype switching. Also disclosed are derivatives of the human antibodies (e.g., bispecific antibodies and immunoconjugates), pharmaceutical compositions comprising the human antibodies, non-human transgenic animals and hybridomas which produce the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.
    Type: Application
    Filed: April 4, 2008
    Publication date: December 23, 2010
    Applicant: MEDAREX, INC.
    Inventors: Tibor Keler, Robert Graziano, John Treml, Yashwant M. Deo
  • Human CTLA-4 Antibodies and Their Uses
    Publication number: 20100047244
    Abstract: The present invention provides novel human sequence antibodies against human CTLA-4 and methods of treating human diseases, infections and other conditions using these antibodies.
    Type: Application
    Filed: September 22, 2009
    Publication date: February 25, 2010
    Applicant: Medarex, Inc.
    Inventors: Alan J. Korman, Edward L. Halk, Nils Lonberg, Yashwant M. Deo, Tibor P. Keler
  • Human CTLA-4 antibodies and their uses
    Patent number: 7605238
    Abstract: The present invention provides human sequence antibodies against human CTLA-4 and methods of treating human diseases, infections and other conditions using these antibodies.
    Type: Grant
    Filed: September 7, 2001
    Date of Patent: October 20, 2009
    Assignee: Medarex, Inc.
    Inventors: Alan J. Korman, Edward L. Halk, Nils Lonberg, Yashwant M. Deo, Tibor P. Keler
  • Cell lines and methods for producing proteins
    Publication number: 20090253176
    Abstract: The methods of the present invention involve the manipulation and/or propagation of oviduct tumor cells derived from either wild-type or transgenic avians.
    Type: Application
    Filed: June 5, 2009
    Publication date: October 8, 2009
    Inventors: Stephen H. Parker, Yashwant M. Deo
  • Human monoclonal antibodies to dendritic cells
    Patent number: 7563876
    Abstract: Isolated human monoclonal antibodies and antigen-binding portions thereof which specifically bind to dendritic cells are disclosed. Also disclosed are bispecifics, immunotoxins and antigen conjugates which include the antibodies or antibody portions. The human antibodies can be produced in a non-human transgenic animal, e.g., a transgenic mouse, capable of producing multiple isotypes of human monoclonal antibodies by undergoing V-D-J recombination and isotype switching. Also disclosed are pharmaceutical compositions comprising the human antibodies, non-human transgenic animals and hybridomas which produce the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.
    Type: Grant
    Filed: May 8, 2001
    Date of Patent: July 21, 2009
    Assignee: CellDex Therapeutics, Inc.
    Inventors: Yashwant M. Deo, Tibor Keler, John Treml
  • Molecular conjugates comprising human monoclonal antibodies to dendritic cells
    Patent number: 7560534
    Abstract: Molecular conjugates comprising an antigen linked to a human monoclonal antibody that specifically binds to dendritic cells are disclosed. Also disclosed are pharmaceutical compositions comprising the molecular conjugates and therapeutic methods for using the conjugates.
    Type: Grant
    Filed: November 7, 2001
    Date of Patent: July 14, 2009
    Assignee: Celldex Research Corporation
    Inventors: Yashwant M. Deo, Tibor Keler, John Treml, Michael Endres