Patents by Inventor Yasmin Chau

Yasmin Chau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11377466
    Abstract: Provided herein are analogs of the natural product icariin represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. The analogs can be used to modulate (e.g., inhibit, such as by competitive inhibition) PDE5 and thereby treat a wide range of PDE5-mediated diseases, including cardiovascular, gastrointestinal, pulmonary, musculoskeletal, neurological and reproductive diseases. Also provided herein are compositions and methods including compounds of Structural Formula (I).
    Type: Grant
    Filed: August 7, 2019
    Date of Patent: July 5, 2022
    Assignee: Whitehead Institute for Biomedical Research
    Inventors: Yasmin Chau, Fu-Shuang Li, Jing-Ke Weng
  • Publication number: 20210309684
    Abstract: Provided herein are analogs of the natural product icariin represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. The analogs can be used to modulate (e.g., inhibit, such as by competitive inhibition) PDE5 and thereby treat a wide range of PDE5-mediated diseases, including cardiovascular, gastrointestinal, pulmonary, musculoskeletal, neurological and reproductive diseases. Also provided herein are compositions and methods including compounds of Structural Formula (I).
    Type: Application
    Filed: August 7, 2019
    Publication date: October 7, 2021
    Inventors: Yasmin Chau, Fu-Shuang Li, Jing-Ke Weng