Patents by Inventor Yasuaki Chihara

Yasuaki Chihara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4414216
    Abstract: There are disclosed tetrahydrofuran compounds and analogs thereof of the formula: ##STR1## and pharmaceutically acceptable acid addition salts thereof, wherein X is oxygen or sulfur, R.sup.1 and R.sup.2 are each hydrogen, halogen, lower alkyl or lower alkoxy, and Am is a group of the formula: ##STR2## wherein Z is oxygen or sulfur, R.sup.3 is hydrogen or halogen, R.sup.4 is hydrogen, lower alkyl or phenyl which may be substituted by 1 to 3 substituents at any position(s) on the phenyl nucleus, each substituent being independently selected from halogen, lower alkyl and lower alkoxy, and R.sup.5 is hydrogen or lower alkyl. Such compounds are useful as neuroleptics.
    Type: Grant
    Filed: June 21, 1982
    Date of Patent: November 8, 1983
    Assignee: Yoshitomi Phamaceutical Industries, Ltd.
    Inventors: Takeshi Kawakita, Yasuaki Chihara, Takemi Fukuda, Michihide Setoguchi, Tetsuya Tahara
  • Patent number: 4358407
    Abstract: Benzothiazine derivatives represented by the formula ##STR1## wherein R.sub.1 is hydrogen, alkyl, alkoxycarbonyl, alkoxalyl, phenyl which may optionally have a substituent or substituents, cycloalkyl or aralkyl, R.sub.2 is hydrogen or alkyl, X is sulphur or oxygen, and Y is methylene or ethylene, and acid addition salts thereof. These compounds are useful as analgesic agents, anti-inflammatory agents, anti-allergic agents, anti-arthritic agents, circulation-improving agents or like pharmaceutics.
    Type: Grant
    Filed: August 24, 1981
    Date of Patent: November 9, 1982
    Assignee: Yoshitomi Pharmaceutical Industries Ltd.
    Inventors: Tetsuo Yokobe, Mitsuru Masago, Yasuaki Chihara, Yutaka Maruyama
  • Patent number: 4005084
    Abstract: Morpholine compounds of the formula: ##STR1## wherein each of R.sup.1 and R.sup.2 is a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, and pharmaceutically acceptable acid addition salts thereof, have strong inhibitory activities on peptic ulcer, gastric motility and gastric secretion but have very weak acetylcholine antagonistic activity.
    Type: Grant
    Filed: July 10, 1975
    Date of Patent: January 25, 1977
    Assignee: Yoshitomi Pharmaceutical Industries, Ltd.
    Inventors: Tomio Muro, Yasuaki Chihara, Sogo Fukuzawa, Kiyoshi Ogawa, Akira Nakanishi
  • Patent number: 3954776
    Abstract: 1-[Methylated piperidino (and pyrrolidin-1-yl)]-3-(substituted phenoxy)-2-propanols of the formula: ##SPC1##Wherein R is a 2-thienylmethyl group, a 2-pyridylmethyl group, a 2-pyridyl group, a tetrahydrofurfuryloxy group, a furfuryloxy group, a 2-thienylmethoxy group, a 2-pyridyloxy group or a group of the formula R.sup.5 --X--A--O-- wherein R.sup.5 is a lower alkyl group, X is --O--, --S-- or --SO.sub.2 --, and A is a lower alkylene group or a --CH.sub.2 --C.ident.C--CH.sub.2 -- group, R.sup.1 is a hydrogen atom, a lower alkyl group or a halogen atom, R.sup.2, R.sup.3 and R.sup.4 are each a hydrogen atom or a methyl group, and n is zero or 1, and pharmaceutically acceptable acid addition and quarternary ammonium salts thereof are disclosed. They exhibit antiarrhythmic action, local anaesthetic action, analgesic action and gastric juice secretion inhibiting action.
    Type: Grant
    Filed: August 23, 1974
    Date of Patent: May 4, 1976
    Assignee: Yoshitomi Pharmeceutical Industries, Ltd.
    Inventors: Tomio Muro, Sogo Fukuzawa, Yasuaki Chihara, Tohru Nakao, Kiyoshi Ogawa