Patents by Inventor Yasuaki Matsubara

Yasuaki Matsubara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 5-substituted-2-phenylamino benzamides as MEK inhibitors
    Patent number: 8575391
    Abstract: An objective of the present invention is to provide compounds that exhibit strong MEK-inhibiting activity and are stable in vivo and soluble in water, which can be used as preventive or therapeutic agents for proliferative diseases. The compounds of the present invention and pharmaceutically acceptable salts thereof are represented by the following formula (1): [where R1, R2, R3, R4, and X are the same as defined in the present patent application].
    Type: Grant
    Filed: April 1, 2010
    Date of Patent: November 5, 2013
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Yoshiaki Isshiki, Yasunori Kohchi, Eisaku Mizuguchi, Hitoshi Iikura, Yasuaki Matsubara, Shinji Tsujii, Nobuo Shimma, Masanori Miwa, Satoshi Aida, Masami Kohchi, Takeshi Murata, Kosuke Aso
  • 4-phenylamino-benzaldoxime derivatives and uses thereof as mitogen-activated protein kinase kinase (MEK) inhibitors
    Patent number: 8084645
    Abstract: A compound of the present invention, or a pharmaceutically acceptable salt thereof is indicated by formula (1) below: wherein, R1, R2, R3, R4, R5, R6, Q, R8, and R9 have the same meanings as R1, R2, R3, R4, R5, R6, Q, R8, and R9 in the specification.
    Type: Grant
    Filed: September 16, 2004
    Date of Patent: December 27, 2011
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Yoshiaki Isshiki, Yasunori Kohchi, Kazuo Hattori, Nobuo Shimma, Masanori Miwa, Naohito Inagaki, Hitoshi Iikura, Yasuaki Matsubara
  • 5-Substituted-2-Phenylamino Benzamides as Mek Inhibitors
    Publication number: 20100197676
    Abstract: An objective of the present invention is to provide compounds that exhibit strong MEK-inhibiting activity and are stable in vivo and soluble in water, which can be used as preventive or therapeutic agents for proliferative diseases. The compounds of the present invention and pharmaceutically acceptable salts thereof are represented by the following formula (1): [where R1, R2, R3, R4, and X are the same as defined in the present patent application].
    Type: Application
    Filed: April 1, 2010
    Publication date: August 5, 2010
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Yoshiaki Isshiki, Yasunori Kohchi, Eisaku Mizuguchi, Hitoshi Iikura, Yasuaki Matsubara, Shinji Tsujii, Nobuo Shimma, Masanori Miwa, Satoshi Aida, Masami Kohchi, Takeshi Murata, Kosuke Aso
  • 5-Substituted-2-phenylamino benzamides as MEK inhibitors
    Patent number: 7745663
    Abstract: An objective of the present invention is to provide compounds that exhibit strong MEK-inhibiting activity and are stable in vivo and soluble in water, which can be used as preventive or therapeutic agents for proliferative diseases. The compounds of the present invention and pharmaceutically acceptable salts thereof are represented by the following formula (1): [where R1, R2, R3, R4, and X are the same as defined in the present patent application].
    Type: Grant
    Filed: July 26, 2005
    Date of Patent: June 29, 2010
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Yoshiaki Isshiki, Yasunori Kohchi, Eisaku Mizuguchi, Hitoshi Iikura, Yasuaki Matsubara, Shinji Tsujii, Nobuo Shimma, Masanori Miwa, Satoshi Aida, Masami Kohchi, Takeshi Murata, Kosuke Aso
  • 5-Substituted-2-Phenylamino Benzamides as MEK Inhibitors
    Publication number: 20090233915
    Abstract: An objective of the present invention is to provide compounds that exhibit strong MEK-inhibiting activity and are stable in vivo and soluble in water, which can be used as preventive or therapeutic agents for proliferative diseases. The compounds of the present invention and pharmaceutically acceptable salts thereof are represented by the following formula (1): [where R1, R2, R3, R4, and X are the same as defined in the present patent application].
    Type: Application
    Filed: July 26, 2005
    Publication date: September 17, 2009
    Inventors: Yoshiaki Isshiki, Yasunori Kohchi, Eisaku Mizuguchi, Hitoshi Iikura, Yasuaki Matsubara, Shinji Tsujii, Nobuo Shimma, Masanori Miwa, Satoshi Aida, Masami Kohchi, Takeshi Murata, Kosuke Aso
  • 4-Phenylamino-benzaldoxime derivatives and uses thereof as mitogen-activated protein kinase kinase (mek) inhibitors
    Publication number: 20070105859
    Abstract: A compound of the present invention, or a pharmaceutically acceptable salt thereof is indicated by formula (1) below: wherein, R1, R2, R3, R4, R5, R6, Q, R8, and R9 have the same meanings as R1, R2, R3, R4, R5, R6, Q, R8, and R9 in the specification.
    Type: Application
    Filed: September 16, 2004
    Publication date: May 10, 2007
    Inventors: Yoshiaki Isshiki, Yasunori Kohchi, Kazuo Hattori, Nobuo Shimma, Masanori Miwa, Naohito Inagaki, Hitoshi IIkura, Yasuaki Matsubara
  • Reference wavelength light generating apparatus
    Patent number: 6552785
    Abstract: A reference wavelength light generating apparatus is disclosed in which light emitted from a light source is branched by a light branching unit, one of the branched lights is extracted as a measuring beam and the other is extracted as reference wavelength light by passing through a collimator and an absorbing member and then being reflected by a reflecting member to return to the branching unit.
    Type: Grant
    Filed: April 17, 2001
    Date of Patent: April 22, 2003
    Assignee: Advantest Corporation
    Inventor: Yasuaki Matsubara
  • Reference wavelength light generating apparatus
    Publication number: 20010055112
    Abstract: A reference wavelength light generating apparatus is disclosed in which light emitted from a light source is branched by a light branching unit, one of the branched lights is extracted as a measuring beam and the other is extracted as reference wavelength light by passing through a collimator and an absorbing member and then being reflected by a reflecting member to return to the branching unit.
    Type: Application
    Filed: April 17, 2001
    Publication date: December 27, 2001
    Inventor: Yasuaki Matsubara