Abstract: The degassing apparatus removes liquid from a vacuum tank (1) with a suction pump (6) and supplies that liquid to a storage tank (9), sprays storage tank liquid into the vacuum tank through a convergent nozzle (7), removes gas from liquid in a state of reduced pressure inside the vacuum tank, and stores the degassed liquid in the storage tank. The storage tank is an airtight hermetically sealed tank provided with a reduced pressure retaining valve that discharges gas accumulated inside the storage tank.

Abstract: A combination including (1) a molecule including the nucleotide sequence of SEQ ID NO: 1 and (2) an anticancer agent; and a method for treating a cancer, including administering an effective amount of the combination to a subject in need thereof. The anticancer agent may be an inhibitor of a BcL2 family molecule. The inhibitor of a BcL2 family molecule may be an expression inhibitor of the BcL2 family molecule or a function inhibitor of the BcL2 family molecule.

Abstract: An RNAi molecule for cancer treatment, including the nucleotide sequence of SEQ ID NO: 1 in an antisense strand; and a method for treating a cancer, including administering an effective amount of the RNAi molecule to a subject in need thereof. The antisense strand includes the nucleotide sequence selected from SEQ ID NOs: 11-30.

Abstract: Provided is a metastasis suppressing agent containing a HSP47 inhibitor.

Abstract: Provided is a medicine containing a HSP47 inhibitor to increase sensitivity of a cancer patient to a chemotherapeutic agent.

Abstract: The degassing apparatus removes liquid from a vacuum tank 1 with a suction pump 6 and supplies that liquid to a storage tank 9, sprays storage tank 9 liquid into a vacuum tank 1 through a convergent nozzle 7, removes gas from liquid in a state of reduced pressure inside the vacuum tank 1, and stores the degassed liquid in the storage tank 9. The storage tank 9 is an airtight hermetically sealed tank provided with a reduced pressure retaining valve that discharges gas accumulated inside the storage tank.

Abstract: This invention provides methods for preventing, treating or ameliorating one or more symptoms of a malignant tumor in a mammal in need thereof, by administering to the mammal a therapeutically effective amount of a composition comprising RNAi molecules, where the RNAi molecules can be active in reducing expression of Hsp47.

Abstract: The present invention provides an array-type photo module including a filter, which, in each channel, transmits therethrough a portion of emitted light from an incident optical fiber on the opposite side of a gradient-index lens array and reflects another portion of the emitted light from the incident optical fiber toward the gradient-index lens array, and a light-shielding member which is arranged on the opposite side of the filter from the gradient-index lens array, so as to be spaced from the filter and, in each channel, has an opening passing therethrough transmitted light from the filter on the opposite side of the filter. The array-type photo module is easily and inexpensively manufactured, and may be used in a high-density array, with low crosstalk.

Abstract: An optical module has a structure for reducing the stress applied to a package. The optical module is structured so that an end face of a waveguide (37) of a planar lightwave circuit (30) is joined to a plurality of packages (40) storing therein optical elements so that the waveguide is optically coupled to the optical elements. The optical module includes a housing (3) storing therein a planar lightwave circuit and a plurality of packages in which an upper face of a protrusion (270) formed in the bottom section is fixed to the planar lightwave circuit (30). Each of the plurality of packages (40) is electrically connected to an electric part (22) provided in the housing (3) via flexible printed circuits (271a, 271b).

Abstract: PROBLEM An object of the present invention is to easily and inexpensively manufacture an array-type photo module and, in addition, coexist high-density array and low crosstalk. SOLUTION The present invention provides an array-type photo module M including a filter 31, which, in each channel, transmits therethrough a portion of emitting light from an incident optical fiber 11 on the opposite side of a gradient-index lens array 2 and reflects another portion of the emitting light from the incident optical fiber 11 toward the gradient-index lens array 2, and a light-shielding member 32 (33) which is arranged on the opposite side of the gradient-index lens array 2 of the filter 31 so as to be spaced from the filter 31 and, in each channel, has an opening 34 (35) passing therethrough transmitted light from the filter 31 on the opposite side of the filter 31.

Abstract: An optical module has a structure for reducing the stress applied to a package. The optical module is structured so that an end face of a waveguide (37) of a planar lightwave circuit (30) is joined to a plurality of packages (40) storing therein optical elements so that the waveguide is optically coupled to the optical elements. The optical module includes a housing (3) storing therein a planar lightwave circuit and a plurality of packages in which an upper face of a protrusion (270) formed in the bottom section is fixed to the planar lightwave circuit (30). Each of the plurality of packages (40) is electrically connected to an electric part (22) provided in the housing (3) via flexible printed circuits (271a, 271b).

Abstract: A bidirectional optical module according to the present invention emits light to an optical fiber and allows returning light from the optical fiber to enter and includes a plurality of light emitting elements that emit light to enter the optical fiber, a light receiving element that receives light having exited the optical fiber, and a non-reciprocal unit for making an optical path in a forward direction from the light emitting element to the optical fiber and an optical path in a backward direction from the optical fiber to the light emitting element different. Then, polarization planes of light incident on the optical fiber after being emitted from the plurality of light emitting elements are mutually orthogonal, and the non-reciprocal unit emits returning light of light emitted from the plurality of light emitting elements from the optical fiber toward the light receiving element to one light receiving element.

Abstract: A bidirectional optical module according to the present invention emits light to an optical fiber and allows returning light from the optical fiber to enter and includes a plurality of light emitting elements that emit light to enter the optical fiber, a light receiving element that receives light having exited the optical fiber, and a non-reciprocal unit for making an optical path in a forward direction from the light emitting element to the optical fiber and an optical path in a backward direction from the optical fiber to the light emitting element different. Then, polarization planes of light incident on the optical fiber after being emitted from the plurality of light emitting elements are mutually orthogonal, and the non-reciprocal unit emits returning light of light emitted from the plurality of light emitting elements from the optical fiber toward the light receiving element to one light receiving element.

Abstract: A packaging platform for optically coupling one or more optical waveguides of one or more optical components having the optical waveguide to one or more optical fibers is provided with a reference structure portion for the horizontal and vertical positioning of the optical component. The platform is further provided with one or more fiber positioning portions for inserting and holding the optical fiber and positioning the optical fiber at a position where the optical fiber is optically connected to the optical waveguide. The provided packaging platform and an optical module using the platform can simplify all alignment steps for optical coupling, electrical connection and sealing in the coupling of the optical component and the optical fiber.

Abstract: A plastic ferrule for an optical connector comprises a cylindrical portion having one insertion hole for fixing an optical fiber and directly related to connection, a holding portion for allowing the cylindrical portion to be stably held in an optical connector, and an guiding portion for allowing an optical fiber to be guided into the ferrule. The ferrule has a hollow, cylindrical hole centering around the insertion hole inside the cylindrical portion. Thus, the ferrule has excellent dimensional accuracy of the outer diameter, and achieves connection of single mode fibers excellent in connection reliability and economy.

Abstract: According to a first aspect of the invention, an optical position sensor employs a position encoder having collimators and reflectors with mutually aligned optical axes mounted in a support. A slotted code plate moves between the collimators and reflectors in a plane non-perpendicular to their optic axes. This encoder converts position to optical signals reliably, regardless of mechanical shock or vibration. According to a second aspect of the invention, an optical position sensing system employs wavelength-division multiplexing to distribute light pulses to different position encoders and time-division multiplexing to further distribute pluses to the collimators in each encoder. This permits multiple position encoders to be served by a single light source and optical fiber.

Abstract: A developing apparatus is used for developing a photoconductive drum in a copying machine. The developing apparatus comprises a following developing roller for developing said photoconductive drum, an opposing developing roller for developing a photoconductive drum before the following developing roller, a supply mechanism for supplying developer to the developing rollers, a developer-quantity-regulator plate disposed between the following developing roller and the supply mechanism, and a limiting plate for limiting the length of the magnetic brush formed on the following developing roller. The distance between the photoconductive drum and the opposing developing roller is larger than the distance between the photoconductive drum and the following developing roller. The regulator plate is disposed apart from the developing rollers at a distance longer than the length of their magnetic brushes.

Abstract: In an optical amplifier, light incident on a first port of a port separator is emitted out of a third port, and is input into and amplified in a semiconductor laser. Amplified light receives the first amount of rotation, e.g., a 45.degree. rotation, of the direction of polarization in a Faraday rotator assembly and is emitted outward. Light emitted out of the Faraday rotator assembly is reflected by the reflector. Passed through the Faraday rotator assembly backward, receives the second amount of rotation, e.g., a further 45.degree. rotation, of the direction of polarization in the same direction as the previous rotation, and is input into the semiconductor laser. The input light is amplified again in the semiconductor laser, is input in the third port of the port separator, and is emitted outward from a second port.

Abstract: A fiber input/output type semiconductor optical amplifier module is disclosed. The optical amplifier module of the present invention, a semiconductor laser amplifier chip is provided for direct amplification of signal light beam. An optical coupling between the semiconductor laser chip and an input/output fibers is taken with a remote coupling using a parallel light beam. Collimator lenses are provided for converting the lightwave signal into a parallel light beam. Two optical isolators are provided for preventing a self-lasing of the semiconductor laser chip. One of the isolators is inserted on an input side of the semiconductor laser chip, and the other is inserted on an output side of the chip. An interference filter and a beam splitter are disposed in the output side of the semiconductor laser chip. The beam splitter splits the output signal of the semiconductor laser chip for monitoring an output power of the chip.

Abstract: A high power pump light source for optical direct amplifier using the stimulated Raman effect is obtained by using a plurality of semiconductor lasers each of which provides low output power. More than two beams of the same wavelength generated by semiconductor lasers are combined (polarization multiplex) by using a polarization prism block, which provides sufficient high power pump light for the stimulated Raman effect amplifier. The output of said polarization prism block is wavelength division multiplexed with signal light to be amplified by using an interference filter block, the output of which is applied to a transmission optical fiber in which amplification of said signal light is effected.