Abstract: A slit lamp microscope of an aspect example includes an illumination system, first photographing system, fixation system, movement mechanism, and controller. The illumination system projects slit light onto an anterior segment of a subject's eye from a first direction. The first photographing system photographs the anterior segment onto which the slit light is being projected, from a second direction different from the first direction. The fixation system outputs fixation light for fixation of the subject's eye. The movement mechanism moves the illumination system and the first photographing system. the controller performs a first control for the movement mechanism to move at least the illumination system and a second control for the first photographing system to photograph the anterior segment a plurality of times in parallel with each other while causing the fixation system to output the fixation light.

Abstract: An illumination system of an ophthalmologic apparatus of an exemplary embodiment projects illumination light from a light source onto the anterior eye segment of a subject's eye. An interference photographing system photographs an interference pattern formed on the cornea by the illumination light. An anterior eye segment photographing system photographs the anterior eye segment onto which the illumination light is being projected. A first optical path coupling element couples the optical path of the interference photographing system and the optical path of the anterior eye segment photographing system with one another.

Abstract: A slit lamp microscope of some embodiment examples includes an illumination system, first photographing system, first movement mechanism, and controller. The illumination system includes a slit forming unit that forms a slit for generating slit light and projects the slit light onto an anterior segment of a subject's eye from a first direction. The first photographing system photographs the anterior segment onto which the slit light is being projected, from a second direction different from the first direction. The first movement mechanism moves a movable portion that includes at least the slit forming unit. The controller performs a first control for the first movement mechanism to move the movable portion and a second control for the first photographing system to photograph the anterior segment a plurality of times in parallel with each other.

Abstract: An OCT imaging method of some exemplary aspects includes acquiring a first three dimensional data set by applying an OCT scan targeting a first three dimensional region of a sample, creating a first two dimensional map based on representative intensity values respectively of a plurality of pieces of A-scan data included in the first three dimensional data set, designating a second three dimensional region of the sample based on the first two dimensional map, acquiring a second three dimensional data set by applying an OCT scan targeting the second three dimensional region, and generating image data from at least part of the second three dimensional data set.

Abstract: An exemplary aspect is a method of processing data acquired by applying an optical coherence tomography (OCT) scan to a sample. The method includes preparing a three dimensional data set acquired from a sample, creating a two dimensional map based on representative intensity values of a plurality of pieces of A-scan data included in the three dimensional data set, placing the three dimensional data set based on the two dimensional map, and executing a process based on at least a partial data set of the three dimensional data set on which placement based on the two dimensional map has been performed.

Abstract: An OCT apparatus of an exemplary aspect includes an OCT scanner, image data generating unit, registration unit, and image data composing unit. The OCT scanner is configured to acquire three dimensional data sets by applying an OCT scan to mutually different three dimensional regions of a sample. The image data generating unit is configured to generate a plurality of pieces of image data from the three dimensional data sets. The registration unit is configured to perform a first registration between the plurality of pieces of image data by applying an image correlation calculation to each of overlap regions in the plurality of pieces of image data. The image data composing unit is configured to compose the plurality of pieces of image data based on a result of the first registration.

Abstract: An ophthalmic system of an embodiment includes a slit lamp microscope and an information processing apparatus. The slit lamp microscope includes an image acquisition device that acquires a three dimensional image by photographing a subject's eye, and a first communication device that transmits the three dimensional image to the information processing apparatus. The information processing apparatus includes a second communication device that receives the three dimensional image transmitted by the first communication device, a display controller that displays a first image based on the three dimensional image on a display device, a partial region designation processor that designates a partial region of the first image, and a rendering processor that renders the three dimensional image based on the partial region to construct a second image. The display controller displays the second image on the display device.

Abstract: A machine learning model is trained to identify the texture difference between the different layers of a multilayer object. By training with data in full 3D space, the resulting model is capable of predicting the probability that each pixel in a 3D image belongs to a certain layer. With the resulting probability map, comparing probabilities allows one to determine boundaries between layers, and/or other properties and useful information such as volume data.

Abstract: An ophthalmic system of an embodiment includes a slit lamp microscope, three dimensional image constructing unit, rendering processor, display controller, report creating unit, and report output unit. The slit lamp microscope includes a front image acquiring unit that photographs an anterior eye segment to acquire a front image, and an image collecting unit that photographs the anterior eye segment with slit light to collect a plurality of images. The three dimensional image constructing unit constructs a three dimensional image based on the collected images. The rendering processor applies rendering to the three dimensional image to construct a rendered image. The display controller displays the front image and the rendered image on a display device. The report creating unit includes a user interface used for creating a report on information displayed. The report output unit outputs the report.

Abstract: A patient management system of an embodiment includes a server, a plurality of ophthalmic examination apparatuses assigned to a plurality of patients, and a plurality of computers installed in a plurality of medical institutions. The ophthalmic examination apparatuses and computers are communicable with the server via a communication line. The server manages the account of each patient, and the account of each medical institution. Test data obtained by each of the ophthalmic examination apparatuses is stored in the account of a corresponding patient. The server sends information stored in the account of a patient to a computer installed in one of the medical institutions assigned in advance to the patient.

Abstract: An ophthalmologic apparatus according to the embodiments includes an OCT optical system, an alignment unit, an image forming unit, a first calculator, and a second calculator. The OCT optical system is configured to acquire OCT data of a fundus of a subject's eye by projecting measurement light onto the fundus. The alignment unit is configured to perform alignment of the OCT optical system with reference to a predetermined site of the subject's eye. The image forming unit is configured to form a tomographic image of the fundus based on the OCT data acquired by the OCT optical system which has been aligned by the alignment unit. The first calculator is configured to calculate a first tilt angle of the tomographic image. The second calculator is configured to calculate a second tilt angle of the fundus by correcting the first tilt angle based on alignment result of the OCT optical system with respect to the predetermined site by the alignment unit.

Abstract: The object of the present invention is to develop an ophthalmologic microscope of a new method that increases the degree of freedom in the optical design in the Galilean ophthalmologic microscope provided with an OCT optical system. The present invention provides an ophthalmologic microscope 1 comprising; an illuminating optical system 300, an observation optical system 400; an objective lens 2; and an OCT optical system 500, characterized in that the optical axis 0-500 of the OCT optical system does not penetrate through the objective lens 2, it comprises objective lens for OCT 507 through which the optical axis 0-500 of the OCT optical system penetrates, and deflection optical elements 503a, 503b for scanning of the OCT optical system and the objective lens for OCT 507 are in a substantially optically conjugate positional relation.

Abstract: An ophthalmologic apparatus of some exemplary embodiments includes an illumination system, interference photographing system, anterior eye segment photographing system, first optical path coupling element, and controller. The illumination system projects illumination light output from a light source, onto the anterior eye segment of a subject's eye. The interference photographing system performs photographing of an interference pattern formed on the cornea by the illumination light. The anterior eye segment photographing system performs photographing of the anterior eye segment onto which the illumination light is being projected. The first optical path coupling element couples the optical path of the interference photographing system and the optical path of the anterior eye segment photographing system with one another.

Abstract: An illumination system of an ophthalmologic apparatus of an exemplary embodiment projects illumination light from a light source onto the anterior eye segment of a subject's eye. An interference photographing system photographs an interference pattern formed on the cornea by the illumination light. An anterior eye segment photographing system photographs the anterior eye segment onto which the illumination light is being projected. A first optical path coupling element couples the optical path of the interference photographing system and the optical path of the anterior eye segment photographing system with one another.

Abstract: An ophthalmologic apparatus according to the embodiments includes an OCT optical system, an alignment unit, an image forming unit, a first calculator, and a second calculator. The OCT optical system is configured to acquire OCT data of a fundus of a subject's eye by projecting measurement light onto the fundus. The alignment unit is configured to perform alignment of the OCT optical system with reference to a predetermined site of the subject's eye. The image forming unit is configured to form a tomographic image of the fundus based on the OCT data acquired by the OCT optical system which has been aligned by the alignment unit. The first calculator is configured to calculate a first tilt angle of the tomographic image. The second calculator is configured to calculate a second tilt angle of the fundus by correcting the first tilt angle based on alignment result of the OCT optical system with respect to the predetermined site by the alignment unit.

Abstract: An ophthalmic apparatus of an exemplary aspect performs the first and second OCT scans on a subject's eye. The first OCT scan is performed on the first region including the first site of the subject's eye, and the second OCT scan is performed on the second region including the second site. The ophthalmic apparatus acquires the first deviation information of the subject's eye prior to the first OCT scan and performs alignment, and also acquires the second deviation information of the subject's eye prior to the second OCT scan and performs alignment. The ophthalmic apparatus calculates the distance between the first site and the second site based on the first data acquired through the first OCT scan and second data acquired through the second OCT scan.

Abstract: The object of the present invention is to develop an ophthalmologic microscope of a new method that increases the degree of freedom in the optical design in the Galilean ophthalmologic microscope provided with an OCT optical system. The present invention provides an ophthalmologic microscope 1, wherein an observation optical system 400, an objective lens 2, and an OCT optical system 500 are placed in such a way that the optical axis of the OCT optical system O-500 does not penetrate through objective lens 2, and the optical axis of the observation optical system O-400 and the optical axis of the OCT optical system O-500 are non-coaxial, and wherein the ophthalmologic microscope further comprises a SLO optical system 1500 that scans a light ray which is a visible ray, a near infrared ray, or an infrared ray and guides the light to the subject's eye so as to become substantially coaxial with the optical axis of the OCT optical system O-500.

Abstract: According to one embodiment, an ophthalmic microscope system includes an illumination system, a pair of light-receiving systems, and an irradiation system. The illumination system is configured to irradiate a subject's eye with illumination light. Each of the light-receiving systems includes a first objective lens and a first imaging device, and is configured to guide the illumination light returning from the subject's eye to the first imaging device through the first objective lens. The objective optical axes of the light-receiving systems are not parallel to each other. The irradiation system is configured to irradiate the subject's eye with light different from the illumination light from a direction different from the objective optical axes.

Abstract: A machine learning model is trained to identify the texture difference between the different layers of a multilayer object. By training with data in full 3D space, the resulting model is capable of predicting the probability that each pixel in a 3D image belongs to a certain layer. With the resulting probability map, comparing probabilities allows one to determine boundaries between layers, and/or other properties and useful information such as volume data.

Abstract: An ophthalmic system of an embodiment includes a slit lamp microscope and an information processing apparatus. The slit lamp microscope includes an image acquisition device that acquires a three dimensional image by photographing a subject's eye, and a first communication device that transmits the three dimensional image to the information processing apparatus. The information processing apparatus includes a second communication device that receives the three dimensional image transmitted by the first communication device, a display controller that displays a first image based on the three dimensional image on a display device, a partial region designation processor that designates a partial region of the first image, and a rendering processor that renders the three dimensional image based on the partial region to construct a second image. The display controller displays the second image on the display device.