Patents by Inventor Yasufumi Goto

Yasufumi Goto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Guanidine derivative and medical use thereof
    Patent number: 10662156
    Abstract: A compound has a guanidine skeleton that inhibits the protease activity of MALT1 and exerts a therapeutic or prophylactic effect on autoimmune disease such as psoriasis or allergic disease such as atopic dermatitis. The guanidine derivative is typified by the following formula or a pharmacologically acceptable salt thereof.
    Type: Grant
    Filed: July 28, 2017
    Date of Patent: May 26, 2020
    Assignee: Toray Industries, Inc.
    Inventors: Yoshitaka Numajiri, Keiichi Okimura, Yuki Matsumura, Kennunettsu Asaba, Tomohide Masuda, Kazuyuki Tokumaru, Yasufumi Goto, Shigeo Fujii
  • GUANIDINE DERIVATIVE AND MEDICAL USE THEREOF
    Publication number: 20190233376
    Abstract: A compound has a guanidine skeleton that inhibits the protease activity of MALT1 and exerts a therapeutic or prophylactic effect on autoimmune disease such as psoriasis or allergic disease such as atopic dermatitis. The guanidine derivative is typified by the following formula or a pharmacologically acceptable salt thereof.
    Type: Application
    Filed: July 28, 2017
    Publication date: August 1, 2019
    Inventors: Yoshitaka Numajiri, Keiichi Okimura, Yuki Matsumura, Kennunettsu Asaba, Tomohide Masuda, Kazuyuki Tokumaru, Yasufumi Goto, Shigeo Fujii
  • UTILITY OF HIGH MOLECULAR WEIGHT MELANOMA ASSOCIATED ANTIGEN IN DIAGNOSIS AND TREATMENT OF CANCER
    Publication number: 20110124007
    Abstract: HMW-MAA antibody cocktails and their uses in detecting cancer and isolating cancer cells are disclosed. Also disclosed are methods of detecting cancer based on the presence of an HMW-MAA genomic sequence in circulating DNA, as well as the increased expression of the HMW-MAA gene and the reduced methylation of the HMW-MAA gene promoter in tissues and circulating cells.
    Type: Application
    Filed: December 30, 2010
    Publication date: May 26, 2011
    Inventors: Dave S.B. Hoon, Soldano Ferrone, Minoru Kitago, Yasufumi Goto
  • UTILITY OF HIGH MOLECULAR WEIGHT MELANOMA ASSOCIATED ANTIGEN IN DIAGNOSIS AND TREATMENT OF CANCER
    Publication number: 20110124004
    Abstract: HMW-MAA antibody cocktails and their uses in detecting cancer and isolating cancer cells are disclosed. Also disclosed are methods of detecting cancer based on the presence of an HMW-MAA genomic sequence in circulating DNA, as well as the increased expression of the HMW-MAA gene and the reduced methylation of the HMW-MAA gene promoter in tissues and circulating cells.
    Type: Application
    Filed: December 30, 2010
    Publication date: May 26, 2011
    Inventors: Dave S.B. Hoon, Soldano Ferrone, Minoru Kitago, Yasufumi Goto
  • FUNCTIONAL TOLL-LIKE RECEPTORS (TLR) ON MELANOCYTES AND MELANOMA CELLS AND USES THEREOF
    Publication number: 20090011418
    Abstract: The invention relates to a method of detecting Toll-like receptor (TLR) gene expression or protein activity in a melanocyte or melanoma cell. Also disclosed are a method of modulating TLR gene expression or protein activity in a melanocyte or melanoma cell by contacting the cell with a TLR modulating agent and a method of inhibiting melanoma cell migration (e.g., spreading) by contacting the cell with a TLR inhibitor.
    Type: Application
    Filed: April 24, 2008
    Publication date: January 8, 2009
    Applicant: JOHN WAYNE CANCER INSTITUTE
    Inventors: Dave S.B. HOON, Yasufumi Goto
  • UTILITY OF HIGH MOLECULAR WEIGHT MELANOMA ASSOCIATED ANTIGEN IN DIAGNOSIS AND TREATMENT OF CANCER
    Publication number: 20080076727
    Abstract: HMW-MAA antibody cocktails and their uses in detecting cancer and isolating cancer cells are disclosed. Also disclosed are methods of detecting cancer based on the presence of an HMW-MAA genomic sequence in circulating DNA, as well as the increased expression of the HMW-MAA gene and the reduced methylation of the HMW-MAA gene promoter in tissues and circulating cells.
    Type: Application
    Filed: March 29, 2007
    Publication date: March 27, 2008
    Applicant: John Wayne Cancer Institute
    Inventors: Dave Hoon, Soldano Ferrone, Minoru Kitago, Yasufumi Goto