Patents by Inventor Yasufumi HAYANO

Yasufumi HAYANO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Screening method for pain suppressor and pharmaceutical composition for prevention or treatment of pain
    Patent number: 11407826
    Abstract: The present invention provides a screening method for a pain suppressor, which method comprises using FLRT3 to select a substance capable of inhibiting FLRT3 expression or a substance capable of inhibiting FLRT3 transport to the spinal cord. In addition, the present invention provides a pharmaceutical composition for prevention or treatment of pain, which pharmaceutical composition comprises, as an active ingredient, a substance capable of inhibiting FLRT3 expression or a substance capable of inhibiting FLRT3 transport to the spinal cord.
    Type: Grant
    Filed: February 26, 2020
    Date of Patent: August 9, 2022
    Assignee: Osaka University
    Inventors: Toshihide Yamashita, Yasufumi Hayano, Moe Yamada
  • SCREENING METHOD FOR PAIN SUPPRESSOR AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF PAIN
    Publication number: 20200190184
    Abstract: The present invention provides a screening method for a pain suppressor, which method comprises using FLRT3 to select a substance capable of inhibiting FLRT3 expression or a substance capable of inhibiting FLRT3 transport to the spinal cord. In addition, the present invention provides a pharmaceutical composition for prevention or treatment of pain, which pharmaceutical composition comprises, as an active ingredient, a substance capable of inhibiting FLRT3 expression or a substance capable of inhibiting FLRT3 transport to the spinal cord.
    Type: Application
    Filed: February 26, 2020
    Publication date: June 18, 2020
    Inventors: Toshihide Yamashita, Yasufumi Hayano, Moe Yamada
  • Method of treating pain with an antibody against netrin-4, UNC5B or neogenin
    Patent number: 10640768
    Abstract: The present invention provides a screening method for pain suppressors, which method is characterized by using netrin-4 and/or a netrin-4 receptor to select a substance capable of inhibiting downstream signaling from netrin-4. According to the screening method of the present invention, pain suppressors useful as a preventive or therapeutic medicine for pain can be identified. The present invention also provides a pharmaceutical composition for prevention or treatment of pain, which composition comprises, as an active ingredient, a substance capable of inhibiting downstream signaling from netrin-4.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: May 5, 2020
    Assignee: OSAKA UNIVERSITY
    Inventors: Toshihide Yamashita, Yasufumi Hayano
  • Screening method for pain suppressor and pharmaceutical composition for prevention or treatment of pain
    Patent number: 10611834
    Abstract: The present invention provides a screening method for a pain suppressor, which method comprises using FLRT3 to select a substance capable of inhibiting FLRT3 expression or a substance capable of inhibiting FLRT3 transport to the spinal cord. In addition, the present invention provides a pharmaceutical composition for prevention or treatment of pain, which pharmaceutical composition comprises, as an active ingredient, a substance capable of inhibiting FLRT3 expression or a substance capable of inhibiting FLRT3 transport to the spinal cord.
    Type: Grant
    Filed: February 10, 2016
    Date of Patent: April 7, 2020
    Assignee: Osaka University
    Inventors: Toshihide Yamashita, Yasufumi Hayano, Moe Yamada
  • METHOD OF TREATING PAIN WITH AN ANTIBODY AGAINST NETRIN-4, UNC5B OR NEOGENIN
    Publication number: 20180230469
    Abstract: The present invention provides a screening method for pain suppressors, which method is characterized by using netrin-4 and/or a netrin-4 receptor to select a substance capable of inhibiting downstream signaling from netrin-4. According to the screening method of the present invention, pain suppressors useful as a preventive or therapeutic medicine for pain can be identified. The present invention also provides a pharmaceutical composition for prevention or treatment of pain, which composition comprises, as an active ingredient, a substance capable of inhibiting downstream signaling from netrin-4.
    Type: Application
    Filed: April 10, 2018
    Publication date: August 16, 2018
    Applicant: OSAKA UNIVERSITY
    Inventors: Toshihide YAMASHITA, Yasufumi HAYANO
  • Method of treating pain with an antibody against netrin-4, Unc5B or neogenin
    Patent number: 9970003
    Abstract: The present invention provides a screening method for pain suppressors, which method is characterized by using netrin-4 and/or a netrin-4 receptor to select a substance capable of inhibiting downstream signaling from netrin-4. According to the screening method of the present invention, pain suppressors useful as a preventive or therapeutic medicine for pain can be identified. The present invention also provides a pharmaceutical composition for prevention or treatment of pain, which composition comprises, as an active ingredient, a substance capable of inhibiting downstream signaling from netrin-4.
    Type: Grant
    Filed: August 11, 2014
    Date of Patent: May 15, 2018
    Assignee: OSAKA UNIVERSITY
    Inventors: Toshihide Yamashita, Yasufumi Hayano
  • SCREENING METHOD FOR PAIN SUPPRESSOR AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF PAIN
    Publication number: 20180002419
    Abstract: The present invention provides a screening method for a pain suppressor, which method comprises using FLRT3 to select a substance capable of inhibiting FLRT3 expression or a substance capable of inhibiting FLRT3 transport to the spinal cord. In addition, the present invention provides a pharmaceutical composition for prevention or treatment of pain, which pharmaceutical composition comprises, as an active ingredient, a substance capable of inhibiting FLRT3 expression or a substance capable of inhibiting FLRT3 transport to the spinal cord.
    Type: Application
    Filed: February 10, 2016
    Publication date: January 4, 2018
    Inventors: Toshihide Yamashita, Yasufumi Hayano, Moe Yamada
  • SCREENING METHOD FOR PAIN SUPPRESSORS AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF PAIN
    Publication number: 20160202269
    Abstract: The present invention provides a screening method for pain suppressors, which method is characterized by using netrin-4 and/or a netrin-4 receptor to select a substance capable of inhibiting downstream signaling from netrin-4. According to the screening method of the present invention, pain suppressors useful as a preventive or therapeutic medicine for pain can be identified. The present invention also provides a pharmaceutical composition for prevention or treatment of pain, which composition comprises, as an active ingredient, a substance capable of inhibiting downstream signaling from netrin-4.
    Type: Application
    Filed: August 11, 2014
    Publication date: July 14, 2016
    Applicant: OSAKA UNIVERSITY
    Inventors: Toshihide YAMASHITA, Yasufumi HAYANO