Patents by Inventor Yasufumi Hirata

Yasufumi Hirata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel 2-guanidinothiazoline compounds, and process for preparing them
    Patent number: 4609737
    Abstract: Novel 2-guanidinothiazoline compounds of the general formula ##STR1## wherein R represents a hydrogen atom or a lower alkyl group, and X represents a halogen atom, and the acid addition salts thereof; they are important intermediate compounds for preparing famotidine and thiotidine which are medicaments useful as gastric acid secretion inhibitors.
    Type: Grant
    Filed: June 7, 1985
    Date of Patent: September 2, 1986
    Assignee: Yamanouchi Pharmaceutical Co., Ltd.
    Inventors: Yasufumi Hirata, Isao Yanagisawa
  • 2-Guanidinothiazoline compounds, and process for preparing them
    Patent number: 4562261
    Abstract: Novel 2-guanidinothiazoline compounds of the general formula ##STR1## wherein R represents a hydrogen atom or a lower alkyl group, and X represents a halogen atom, and the acid addition salts thereof; they are important intermediate compounds for preparing famotidine and thiotidine which are medicaments useful as gastric acid secretion inhibitors.
    Type: Grant
    Filed: April 5, 1984
    Date of Patent: December 31, 1985
    Assignee: Yamanouchi Pharmaceutical Co., Ltd.
    Inventors: Yasufumi Hirata, Isao Yanagisawa
  • Antisecretory imidazole amidine compounds, composition and method of use
    Patent number: 4379158
    Abstract: Novel heterocyclic compounds shown by the formula ##STR1## wherein Het represents a 5-membered or 6-membered heterocyclic group which may have substituent(s); Z represents a sulfur atom or oxygen atom; X represents an oxygen atom or the unsubstituted or substituted imino group shown by N--R.sub.1 (wherein R.sub.
    Type: Grant
    Filed: October 3, 1980
    Date of Patent: April 5, 1983
    Assignee: Yamanouchi Pharmaceutical Co., Ltd.
    Inventors: Yasufumi Hirata, Isao Yanagisawa, Toshinari Tamura, Masaaki Takeda
  • Guanidinothiazole compounds, and medical compositions containing them
    Patent number: 4362736
    Abstract: Novel guanidinothiazole compounds of the general formula ##STR1## wherein R represents a hydrogen atom or a lower alkyl group, Y represents a sulfur atom or a methylene group, m and n each represents an integer of 1-3, A represents the group shown by ##STR2## (wherein R.sub.1 represents a hydrogen atom, a cyano group, a carbamoyl group, a ureido group, a hydroxyl group, a lower alkoxy group, a lower acyl group, an acylamino group, an arylsulfamoyl group, an aralkyl group or a carboxymethyl group, an arylsulfamoyl group, an aralkyl group or a carboxymethyl group, R.sub.2 represents a hydrogen atom, a lower alkyl group, a lower alkenyl group, a lower alkynyl group, a cyano group or a lower acyl group, and R.sub.3 represents a hydrogen atom, a lower alkyl group, a hydroxyl group or a sulfamoyl group), and the pharmacologically acceptable acid addition salts thereof; these compounds are useful as gastric acid secretion inhibitors.
    Type: Grant
    Filed: March 6, 1980
    Date of Patent: December 7, 1982
    Assignee: Yamanouchi Pharmaceutical Co., Ltd.
    Inventors: Yasufumi Hirata, Isao Yanagisawa, Yoshio Ishii, Masaaki Takeda
  • Guanidinothiazole compounds, process for preparation and gastric inhibiting compositions containing them
    Patent number: 4283408
    Abstract: Novel guanidinothiazole compounds of the general formula ##STR1## wherein R represents a hydrogen atom or a lower alkyl group, R.sub.1 represents an amino group, a lower alkyl group, a halogeno lower alkyl group, a substituted- or unsubstituted-aryl group, a mono- or di-lower alkylamino group, an arylamino group or an aralkylamino group, R.sub.2 represents a hydrogen atom, a lower alkyl group, a lower alkenyl group or a lower alkynyl group, Y represents a sulfur atom or a methylene group, m and n, each represents an integer of 1-3, and the pharmacologically acceptable acid addition salts thereof, they are useful as gastric acid secretion inhibitors.
    Type: Grant
    Filed: December 27, 1979
    Date of Patent: August 11, 1981
    Assignee: Yamanouchi Pharmaceutical Co., Ltd.
    Inventors: Yasufumi Hirata, Isao Yanagisawa, Yoshio Ishii, Shinichi Tsukamoto, Noriki Ito, Yasuo Isomura, Masaaki Takeda
  • Antisecretory heterocyclic amidine compounds
    Patent number: 4252819
    Abstract: Novel heterocyclic compounds shown by the formula ##STR1## wherein Het represents a 5-membered or 6-membered heterocyclic group which may have substituent(s); Z represents a sulfur atom or oxygen atom; X represents an oxygen atom or the unsubstituted or substituted imino group shown by N--R.sub.1 (wherein R.sub.
    Type: Grant
    Filed: August 16, 1978
    Date of Patent: February 24, 1981
    Assignee: Yamanouchi Pharmaceutical Co., Ltd.
    Inventors: Yasufumi Hirata, Isao Yanagisawa, Toshinari Tamura, Masaaki Takeda
  • N-1-Benzyl-3-pyrrolidinyl-4-dimethylamino benzamide derivatives
    Patent number: 4197243
    Abstract: The compounds of this invention are strong central nervous system depressants, in particular strong antipsychotics.
    Type: Grant
    Filed: May 15, 1978
    Date of Patent: April 8, 1980
    Assignee: Yamanouchi Pharmaceutical Co., Ltd.
    Inventors: Masuo Murakami, Kozo Takahashi, Yasufumi Hirata, Mutsuo Takashima, Sumio Iwanami, Osamu Hasegawa, Yoshihisa Nozaki, Shiro Tachikawa, Masaaki Takeda, Shinji Usuda
  • Pyrrolidinyl and piperidinyl benzamide derivatives
    Patent number: 4097487
    Abstract: The compounds of this invention are strong central nervous system depressants, in particular strong antipsychotics.
    Type: Grant
    Filed: March 29, 1976
    Date of Patent: June 27, 1978
    Assignee: Yamanouchi Pharmaceutical Co., Ltd.
    Inventors: Masuo Murakami, Kozo Takahashi, Yasufumi Hirata, Mutsuo Takashima, Sumio Iwanami, Osamu Hasegawa, Yoshihisa Nozaki, Shiro Tachikawa, Masaaki Takeda, Shinji Usuda