Patents by Inventor Yasufumi Nishikura

Yasufumi Nishikura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method Of Screening Candidate Drug
    Publication number: 20090047655
    Abstract: It is intended to provide a method of screening a candidate drug mainly metabolized by a drug metabolizing enzyme, CYP2D6, CYP2C9 or CYP2C19 with the use of a chimeric mouse carrying human hepatocytes transplanted thereinto, whereby it is determined whether or not the candidate drug is metabolized in a subject deficient in CYP2D6, CYP2C9 or CYP2C19. It is also intended to provide a method of determining whether or not a candidate drug induces or inhibits the activity of any of drug metabolizing enzymes, CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP3A4 with the use of a chimeric mouse carrying human hepatocytes transplanted thereinto.
    Type: Application
    Filed: November 16, 2005
    Publication date: February 19, 2009
    Inventors: Chise Mukaidani, Katsutoshi Yoshizato, Yasufumi Nishikura, Toru Horie, Hiroshi Nakazawa, Hiroshi Kanamaru, Chiaki Ueda, Chiemi Hine