Abstract: The present disclosure provides a compound having a STING agonistic activity, which may be expected to be useful as an agent for the prophylaxis or treatment of STING-related diseases. The present disclosure relates to a compound represented by the formula (I): wherein each symbol is as defined in the description, or a salt thereof.

Abstract: The radiographic image detection device performs: a radiographic image generation process of reading a pixel signal from a pixel region in a state in which radiation is emitted to generate a radiographic image; a first correction image acquisition process of reading the pixel signal from the pixel region a plurality of times to acquire a plurality of first correction images in a shorter accumulation time than the radiographic image or using binning reading in a state in which the radiation is not emitted immediately before radiography including the radiographic image generation process; a selection process of selecting, as an averaging target, at least two or more of the plurality of first correction images according to a time elapsed since immediately preceding radiography or an amount of variation in a residual image based on the first correction image; and a correction process of correcting the radiographic image on the basis of an average image obtained by averaging the first correction images selected as

Abstract: A radiographic image detection device subtracts a first offset image from a radiographic image to generate a primary corrected image, subtracts a second offset image from an immediately preceding offset image to generate an offset difference image, performs gain correction on the primary corrected image on the basis of a first gain image to generate a secondary corrected image, performs gain correction on the offset difference image on the basis of a second gain image to generate a gain-corrected offset difference image, performs a low-pass filtering process on the gain-corrected offset difference image, and subtracts the gain-corrected offset difference image subjected to the low-pass filtering process from the secondary corrected image to generate a tertiary corrected image.

Abstract: A correction image acquisition process includes: a first gain image acquisition process of reading a pixel signal from a pixel region irradiated with radiation in a state in which a subject is not placed to acquire a first gain image; a pre-irradiation image acquisition process of reading the pixel signal from the pixel region in a state in which the subject is not placed and the radiation is not emitted to acquire a pre-irradiation image; a discarding process of discarding charge accumulated in a pixel of the pixel region after a dose of radiation that saturates the charge is emitted in a state in which the subject is not placed; a post-irradiation image acquisition process of reading the pixel signal from the pixel region to acquire a post-irradiation image after the discarding process is performed; and a second gain image acquisition process of subtracting the pre-irradiation image from the post-irradiation image to acquire a second gain image.

Abstract: At least two first offset images having different accumulation times are acquired in a state in which radiation is not emitted. A pixel signal is read in an accumulation time shorter than that of a plurality of first offset images or using binning reading in a state in which the radiation is not emitted to acquire a second offset image. A reference image is acquired by reading the pixel signal using the same reading method as that used for the second offset image and in a state in which gates of the pixels are turned off. A difference between the two first offset images having different accumulation times is calculated to acquire a first dark current distribution image. A difference between the second offset image and the reference image is calculated to acquire a second dark current distribution image.

Abstract: A correction image acquisition process includes: a first gain image acquisition process of reading a pixel signal from a pixel region irradiated with radiation in a state in which a subject is not placed to acquire a first gain image; a pre-irradiation image acquisition process of reading the pixel signal from the pixel region in a state in which the subject is not placed and the radiation is not emitted to acquire a pre-irradiation image; a discarding process of discarding charge accumulated in a pixel of the pixel region after a dose of radiation that saturates the charge is emitted in a state in which the subject is not placed; a post-irradiation image acquisition process of reading the pixel signal from the pixel region to acquire a post-irradiation image after the discarding process is performed; and a second gain image acquisition process of subtracting the pre-irradiation image from the post-irradiation image to acquire a second gain image.

Abstract: A radiographic image detection device subtracts a first offset image from a radiographic image to generate a primary corrected image, subtracts a second offset image from an immediately preceding offset image to generate an offset difference image, performs gain correction on the primary corrected image on the basis of a first gain image to generate a secondary corrected image, performs gain correction on the offset difference image on the basis of a second gain image to generate a gain-corrected offset difference image, performs a low-pass filtering process on the gain-corrected offset difference image, and subtracts the gain-corrected offset difference image subjected to the low-pass filtering process from the secondary corrected image to generate a tertiary corrected image.

Abstract: At least two first offset images having different accumulation times are acquired in a state in which radiation is not emitted. A pixel signal is read in an accumulation time shorter than that of a plurality of first offset images or using binning reading in a state in which the radiation is not emitted to acquire a second offset image. A reference image is acquired by reading the pixel signal using the same reading method as that used for the second offset image and in a state in which gates of the pixels are turned off. A difference between the two first offset images having different accumulation times is calculated to acquire a first dark current distribution image. A difference between the second offset image and the reference image is calculated to acquire a second dark current distribution image.

Abstract: The radiographic image detection device performs: a radiographic image generation process of reading a pixel signal from a pixel region in a state in which radiation is emitted to generate a radiographic image; a first correction image acquisition process of reading the pixel signal from the pixel region a plurality of times to acquire a plurality of first correction images in a shorter accumulation time than the radiographic image or using binning reading in a state in which the radiation is not emitted immediately before radiography including the radiographic image generation process; a selection process of selecting, as an averaging target, at least two or more of the plurality of first correction images according to a time elapsed since immediately preceding radiography or an amount of variation in a residual image based on the first correction image; and a correction process of correcting the radiographic image on the basis of an average image obtained by averaging the first correction images selected as

Abstract: Disclosed is a technique capable of enhancing usability of a radiographic image capturing apparatus, system, control method of the radiographic image capturing apparatus and a non-transitory computer readable recording medium recorded with a control program, for a user. A radiographic image capturing apparatus includes: an I/F unit and an imaging control unit that function as a communication unit that selectively performs communication with any one of a portable information terminal and a console which are plural control apparatuses that have different image processing capacities with respect to a radiographic image and respectively perform a control relating to capturing of the radiographic image; and an imaging control unit that functions as a selection unit that selects any one of plural imaging modes predetermined with respect to the capturing of the radiographic image according to the image processing capacity of the control apparatus that performs communication with the communication unit.

Abstract: A CPU functions as an acquisition unit and a derivation unit. The acquisition unit acquires a first radiographic image and a second radiographic image respectively generated by a first radiation detector and a second radiation detectors which are irradiated with radiation with first energy emitted from a radiation source in preliminary imaging before main imaging from a radiography apparatus in which the first and second radiation detectors are arranged in a direction in which the radiation is emitted. The derivation unit derives the composition of a soft part of a subject, using the first and second radiographic images acquired by the acquisition unit, and derives second energy of the radiation emitted from the radiation source in the main imaging according to the derived composition of the soft part.

Abstract: A control unit corrects a lag component, which is included in offset image data in a state in which radiation is not emitted for a period from the end of a first imaging operation of generating second radiographic image data in a state in which the radiation is emitted and to the start of a second imaging operation of generating the second radiographic image data in the state in which the radiation is emitted and at each of a plurality of different times elapsed since the first imaging operation, on the basis of a combination of the correction image data and the time elapsed since the first imaging operation, lag component time change information, and a time from the end of the first imaging operation to the start of the second imaging operation, and corrects the second radiographic image data using the corrected offset image data.

Abstract: Provided are a radiography system, a radiography method, a radiography program, and a body thickness estimation apparatus that can estimate the body thickness of a subject using each of radiographic images generated by irradiation with radiations having different energy levels. A radiography system includes a radiography apparatus including two radiation detectors and a console including an estimation unit that estimates the body thickness of a subject on the basis of the ratio of pixel values in a region, which corresponds to a soft tissue of the subject and is a corresponding region of radiographic images generated by the two radiation detectors irradiated with radiations having different energy levels, and correspondence relationship information in which the ratio and the body thickness are associated with each other.

Abstract: A linerless label including a support, a release layer over one surface of the support, and an adhesive layer over another surface of the support, wherein when the linerless label is cut with an apparatus including a mechanism in which an upper blade of cutter blades is immobilized and a lower blade of the cutter blades is configured to move upward, in a manner that the lower blade is inserted into the linerless label from a side of the linerless label at which the adhesive layer is provided, a cutter load voltage during a cutter operation performed after the linerless label is cut five thousand times repeatedly has a difference of less than or equal to 2.0 V from the cutter load voltage during cutting of a label support, which is the linerless label before treated to have adhesiveness.

Abstract: Disclosed is a technique capable of enhancing usability of a radiographic image capturing apparatus, system, control method of the radiographic image capturing apparatus and a non-transitory computer readable recording medium recorded with a control program, for a user. A radiographic image capturing apparatus includes: an I/F unit and an imaging control unit that function as a communication unit that selectively performs communication with any one of a portable information terminal and a console which are plural control apparatuses that have different image processing capacities with respect to a radiographic image and respectively perform a control relating to capturing of the radiographic image; and an imaging control unit that functions as a selection unit that selects any one of plural imaging modes predetermined with respect to the capturing of the radiographic image according to the image processing capacity of the control apparatus that performs communication with the communication unit.

Abstract: A CPU functions as an acquisition unit and a derivation unit. The acquisition unit acquires a first radiographic image and a second radiographic image respectively generated by a first radiation detector and a second radiation detectors which are irradiated with radiation with first energy emitted from a radiation source in preliminary imaging before main imaging from a radiography apparatus in which the first and second radiation detectors are arranged in a direction in which the radiation is emitted. The derivation unit derives the composition of a soft part of a subject, using the first and second radiographic images acquired by the acquisition unit, and derives second energy of the radiation emitted from the radiation source in the main imaging according to the derived composition of the soft part.

Abstract: Disclosed is a technique capable of enhancing usability of a radiographic image capturing apparatus, system, control method of the radiographic image capturing apparatus and a non-transitory computer readable recording medium recorded with a control program, for a user. A radiographic image capturing apparatus includes: an I/F unit and an imaging control unit that function as a communication unit that selectively performs communication with any one of a portable information terminal and a console which are plural control apparatuses that have different image processing capacities with respect to a radiographic image and respectively perform a control relating to capturing of the radiographic image; and an imaging control unit that functions as a selection unit that selects any one of plural imaging modes predetermined with respect to the capturing of the radiographic image according to the image processing capacity of the control apparatus that performs communication with the communication unit.

Abstract: In an image analysis device, an image analysis method, and a non-transitory computer-readable recording medium, it is determined whether a radiographic image is captured by rocking a rocking imaging grid. The image analysis device includes: a radiographic image acquisition section; a dosage data acquisition section that acquires dosage data indicating, in a time-series manner, a dosage of radiation rays exposed to a specific position in an imaging area in a specific period; and a determining section that determines whether the dosage data has a first feature indicating a dosage variation as a plurality of radiation absorbing bodies and a radiation transmitting body disposed between adjacent radiation absorbing bodies pass through a space between the specific position and a radiation source, and determines that the radiographic image corresponding to the dosage data determined to have the first feature is a rocking grid use image captured by rocking a rocking imaging grid.

Abstract: The present disclosure provides an image processing device including: a scattered radiation correction data acquisition section that acquires scattered radiation correction data as a result of radiation being irradiated onto a radiographic imaging device that images a radiographic image; a pixel region acquisition section that acquires information indicating a size of an effective pixel region of the radiographic imaging device; an exposure range acquisition section that acquires information indicating an imaging exposure range of radiation for imaging an imaging subject with the radiographic imaging device; an image data acquisition section that acquires image data as a result of imaging a radiographic image of the imaging subject; and a correction section that corrects the image data acquired by the image data acquisition section using the scattered radiation correction data, in a case in which the imaging exposure range includes an area outside of the effective pixel region.

Abstract: In an image analysis device, an image analysis method, and a non-transitory computer-readable recording medium, it is determined whether a radiographic image is captured by rocking a rocking imaging grid. The image analysis device includes: a radiographic image acquisition section; a dosage data acquisition section that acquires dosage data indicating, in a time-series manner, a dosage of radiation rays exposed to a specific position in an imaging area in a specific period; and a determining section that determines whether the dosage data has a first feature indicating a dosage variation as a plurality of radiation absorbing bodies and a radiation transmitting body disposed between adjacent radiation absorbing bodies pass through a space between the specific position and a radiation source, and determines that the radiographic image corresponding to the dosage data determined to have the first feature is a rocking grid use image captured by rocking a rocking imaging grid.