Abstract: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).

Abstract: The purpose of the present invention is to provide novel complexes that improve the effect of nucleic acid medicines. Provided is a complex in which a multibranched lipid(s) binds through a linker to a strand of an oligonucleotide comprising a nucleic acid medicine having suppressing activity of the target gene expression.

Abstract: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).

Abstract: The purpose of the present invention is to provide novel complexes that improve the effect of nucleic acid medicines. Provided is a complex in which a multibranched lipid(s) binds through a linker to a strand of an oligonucleotide comprising a nucleic acid medicine having suppressing activity of the target gene expression.

Abstract: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).

Abstract: Object of the present invention is to develop an artificial synthesis system of various peptides having an azole derivative structure and develop a library of such peptides.

Abstract: Object of the present invention is to develop an artificial synthesis system of various peptides having an azole derivative structure and develop a library of such peptides.

Abstract: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).

Abstract: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).

Abstract: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).

Abstract: A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or treatment of a disease accompanied by abnormality in ALK, for example, cancer, cancer metastasis, depression or cognitive function disorder: (meanings of the symbols that are included in the formula are as given in the specification).

Abstract: Provided are a carbon catalyst for decomposing a hazardous substance that effectively decomposes hazardous substances such as aldehydes, a hazardous-substance-decomposing material, and a method of decomposing a hazardous substance. The carbon catalyst for decomposing a hazardous substance is a carbon catalyst having a catalytic activity for decomposing the hazardous substance. The hazardous substance is, for example, a volatile organic compound such as aldehydes or a malodorous substance such as a sulfur compound. The method of decomposing a hazardous substance, is a method including decomposing the hazardous substance with the carbon catalyst for decomposing a hazardous substance or with a hazardous-substance-decomposing material containing the carbon catalyst for decomposing a hazardous substance.

Abstract: Provided are a carbon catalyst for decomposing a hazardous substance that effectively decomposes hazardous substances such as aldehydes, a hazardous-substance-decomposing material, and a method of decomposing a hazardous substance. The carbon catalyst for decomposing a hazardous substance is a carbon catalyst having a catalytic activity for decomposing the hazardous substance. The hazardous substance is, for example, a volatile organic compound such as aldehydes or a malodorous substance such as a sulfur compound. The method of decomposing a hazardous substance, is a method including decomposing the hazardous substance with the carbon catalyst for decomposing a hazardous substance or with a hazardous-substance-decomposing material containing the carbon catalyst for decomposing a hazardous substance.

Abstract: There are provided a novel process for producing [{(5Z,7E)-(1S,3R,20S)-1,3-dihydroxy-9,10-secopregna-5,7,10(19),16-tetraen-20-yl}oxy]-N-(2,2,3,3,3-pentafluoropropyl)acetamide, which process is characterized by irradiating a compound represented by the formula: with UV to ring-open the compound, and then isomerizing the resulting compound; an intermediate useful for carrying out the process; and a process for producing the intermediate.

Abstract: There are provided a novel process for producing [{(5Z,7E)-(1S,3R,20S)-1,3-dihydroxy-9,10-secopregna-5,7,10(19),16-tetraen-20-yl}oxy]-N-(2,2,3,3,3-pentafluoropropyl)acetamide, which process is characterized by irradiating a compound represented by the formula: with UV to ring-open the compound, and then isomerizing the resulting compound; an intermediate useful for carrying out the process; and a process for producing the intermediate.

Abstract: The invention provides a glucitol derivative having the function of reducing a blood sugar level and having preferable properties required of medicines, such as long-lasting drug activity; and a medicinal composition for use in the prevention or treatment of diseases attributable to hyperglycemia, such as diabetes, complications of diabetes, and obesity. The derivative is a compound represented by the formula (I): wherein m is an integer selected among 1-3; R1 to R4 each independently is optionally substituted alkyl, etc.; Ar1 is optionally substituted naphthyl; and A is optionally substituted heteroaryl, a prodrug of the compound, or a pharmaceutically acceptable salt of either. Also provided are a medicine, a medicinal composition, and the like each containing the compound.

Abstract: In a process of producing an aromatic compound isomer substituted with alkyl group(s) and/or halogen atom(s), through adsorptive separation by the use of a zeolite-containing adsorbent and a desorbent, the desorbent is, after having been processed for removing impurities from it, supplied to the adsorptive separation step. In the process, the absorbent used is prevented from being degraded, and its life is prolonged to efficiently separate an aromatic compound isomer mixture into individual isomers.

Abstract: A shower apparatus is provided with a plurality of shower discharge ports. More specifically, a shower apparatus is provided, in which hot water remains in a hot water line, that is communicated with the shower discharge ports, after the discharge has been completed. The hot water, which has a lower temperature, is drained through a drain valve for disposal of the water in the hot water line and a drain line. At the beginning of the next shower discharge, cold water is thus prevented from being discharged. The operation of an opening and closing valve for effecting discharge and stoppage of each shower discharge port is controlled according to control programs, so that the shower discharge is automatically controlled. The content of the shower discharge, carried out according to the programs, can be changed by a user through the operation of a control section. Moreover, upon the start of the shower discharge, a sudden jet of water is prevented.

Abstract: The present invention is related to a shower apparatus provided with a plurality of shower discharge ports. More specifically, a shower apparatus is disclosed in which hot water remains in a hot water line connected to several shower discharge ports, after a discharge has been completed. Hot water within the hot water line which has lowered in temperature is drained through a drain valve in order to dispose of the water. At the beginning of the next shower discharge, cold water is prevented from being discharged. The operation of an opening and closing valve for effecting discharge and stoppage of each shower discharge port is controlled according to control programs, whereby the shower discharge is substantially controlled. The content of the shower discharge, carried out according to the programs, can be changed by a user through the operation of a central section. Moreover, upon the start of a shower discharge, a sudden jet of water is prevented.