Abstract: An information acquisition proxy system which conducts mediation for information acquisition between an information accessing terminal and an information distributing server. The system comprises a user authentication section for identifying a user and an information acquisition history managing section for retaining and managing a demand for information acquisition from the information accessing terminal, with the information acquisition history managing section retaining and managing demands in units of users. Also included in the system is an additional information managing section for managing additional information for the demand said information acquisition history managing section manages.

Abstract: The present invention provides a preparation for percutaneous absorption comprising as an effective component a prostaglandin I.sub.2 derivative and a fatty acid or a derivative thereof, or a mixture of two or more of these, which has high percutaneous permeability of the PGI.sub.2 derivative. Particularly, the present invention provides a preparation for percutaneous absorption comprising 5,6,7-trinor-4,8-inter-m-phenylene PGI.sub.2 derivative and a C.sub.6 -C.sub.24 fatty acid, a salt thereof or an ester thereof, or a mixture of two or more of these, which has high percutaneous permeability of the PGI.sub.2 derivative. This preparation for percutaneous absorption suggests a possibility to last pharmacological effects and to reduce side effects. Thus, the preparation is expected to be used for therapy of various diseases, aiming at topical and systemic actions.